alglucerase 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
enzymes 5129 143003-46-7

Description:

MoleculeDescription

Synonyms:

  • alglucerase
  • ceredase
modified form of human placental glucocerebrosidase; oligosaccharide units of glucocerebrosidase are sequentially deglycosylated to yield a mannose-terminated preparation which is targeted to the mannose lectin on the macrophage plasma membrane
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
April 5, 1991 FDA GENZYME

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A16AB01 ALIMENTARY TRACT AND METABOLISM
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Enzymes
FDA CS M0009360 Glucosylceramidase
FDA EPC N0000175820 Hydrolytic Lysosomal Glucocerebroside-specific Enzyme

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Chronic non-neuropathic Gaucher's disease indication 62201009




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02810 KEGG_DRUG
4019586 VANDF
CHEMBL1201633 ChEMBL_ID
C070292 MESH_SUPPLEMENTAL_RECORD_UI
DB00088 DRUGBANK_ID
46049 RXNORM
121 MMSL
4148 MMSL
d00596 MMSL
003586 NDDF
109088000 SNOMEDCT_US
329497002 SNOMEDCT_US
C0102139 UMLSCUI
6866 INN_ID
27T56C7KK0 UNII

Pharmaceutical products:

None