octocog alfa 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
blood factor VIII 5099 139076-62-3

Description:

MoleculeDescription

Synonyms:

  • octocog alfa
  • iblias
  • advate
Octocog alfa (human coagulation factor VIII), is a substance that helps the blood to clot. Patients with haemophilia A lack factor VIII, and this causes blood clotting problems, such as bleeding in the joints, muscles or internal organs. Advate is used to correct the factor VIII deficiency by replacing the missing factor VIII, giving temporary control of the bleeding disorder. Octocog alfa is made by a method known as ‘recombinant DNA technology’, it is made by cells into which a gene (DNA) has been introduced that makes them able to produce it.
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
March 2, 2004 EMA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hereditary factor VIII deficiency disease indication 28293008 DOID:12134




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D05401 KEGG_DRUG
4019616 VANDF
4029702 VANDF
C1691209 UMLSCUI
CHEMBL4297873 ChEMBL_ID
CHEMBL2108455 ChEMBL_ID
CHEMBL2109099 ChEMBL_ID
104815 PUBCHEM_CID
DB00025 DRUGBANK_ID
C078147 MESH_SUPPLEMENTAL_RECORD_UI
4257 RXNORM
90051 MMSL
d00525 MMSL
d05974 MMSL
002035 NDDF
003830 NDDF
278910002 SNOMEDCT_US
416523005 SNOMEDCT_US
418888003 SNOMEDCT_US
422675008 SNOMEDCT_US
C0015506 UMLSCUI

Pharmaceutical products:

None