carfecillin indications/contra

Stem definitionDrug idCAS RN
antibiotics, 6-aminopenicillanic acid derivatives 507 27025-49-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • carfecillin sodium
  • BRL-3475
  • carfecillin
  • carbenicillin phenyl
  • carbenicillin phenyl ester
The phenyl ester of CARBENICILLIN that, upon oral administration, is broken down in the intestinal mucosa to the active antibacterial. It is used for urinary tract infections.
  • Molecular weight: 454.50
  • Formula: C23H22N2O6S
  • CLOGP: 3.17
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 2
  • TPSA: 113.01
  • ALOGS: -4.40
  • ROTB: 7

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC G01AA08 GENITO URINARY SYSTEM AND SEX HORMONES
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Antibiotics
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000892 Anti-Infective Agents, Urinary
MeSH PA D012076 Renal Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.79 acidic
pKa2 10.83 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0085959 UMLSCUI
D02199 KEGG_DRUG
417288007 SNOMEDCT_US
N0000166995 NDFRT
350166000 SNOMEDCT_US
9UU4XDB74X UNII
3487 INN_ID
33672 PUBCHEM_CID
CHEMBL1095283 ChEMBL_ID
D002323 MESH_DESCRIPTOR_UI
CHEMBL2105996 ChEMBL_ID
DB00578 DRUGBANK_ID
CHEBI:3414 CHEBI

Pharmaceutical products:

None