carbuterol indications/contra

Stem definitionDrug idCAS RN
bronchodilators, phenethylamine derivatives 506 34866-47-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • carbuterol hydrochloride
  • carbuterol
  • carbuterol HCl
sympathomimetric specific for beta2 receptors; proposed bronchodilator agent; minor descriptor (78-86); on-line & INDEX MEDICUS search ETHANOLAMINES (78-86); RN given refers to parent cpd
  • Molecular weight: 267.33
  • Formula: C13H21N3O3
  • CLOGP: -0.15
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 5
  • TPSA: 107.61
  • ALOGS: -2.49
  • ROTB: 5

Drug dosage:

DoseUnitRoute
6 mg O

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC R03AC10 RESPIRATORY SYSTEM
DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
ADRENERGICS, INHALANTS
Selective beta-2-adrenoreceptor agonists
ATC R03CC10 RESPIRATORY SYSTEM
DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
ADRENERGICS FOR SYSTEMIC USE
Selective beta-2-adrenoreceptor agonists

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.97 acidic
pKa2 13.21 acidic
pKa3 13.81 acidic
pKa4 9.13 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
D03402 KEGG_DRUG
0N12JR32MR UNII
3360 INN_ID
36976 PUBCHEM_CID
006835 NDDF
CHEBI:135100 CHEBI
C100249 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL2106022 ChEMBL_ID
CHEMBL2110780 ChEMBL_ID
34866-46-1 SECONDARY_CAS_RN

Pharmaceutical products:

None