tannic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5039 1401-55-4

Description:

MoleculeDescription

Synonyms:

  • tannic acid
  • tannin
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Feb. 2, 1980 FDA ARMOUR PHARM

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Carbonic anhydrase 2 Enzyme Ki 4.48 CHEMBL
Carbonic anhydrase 1 Enzyme Ki 4.12 CHEMBL
3-hydroxy-3-methylglutaryl-coenzyme A reductase Enzyme IC50 5.50 CHEMBL
Cytochrome P450 2C9 Enzyme IC50 5.34 CHEMBL
Cytochrome P450 1A2 Enzyme IC50 6.04 CHEMBL
cGMP-specific 3',5'-cyclic phosphodiesterase Enzyme IC50 5.33 CHEMBL
Tyrosine-protein kinase Lck Kinase IC50 7.10 CHEMBL
Tyrosine-protein kinase Fyn Kinase IC50 7.66 CHEMBL
Thromboxane-A synthase Enzyme IC50 6.49 CHEMBL
Carbonic anhydrase 6 Enzyme Ki 4.75 CHEMBL
Mitogen-activated protein kinase 3 Kinase IC50 5.39 CHEMBL
Mitogen-activated protein kinase 14 Kinase IC50 6.43 CHEMBL
Mitogen-activated protein kinase 1 Kinase IC50 6.73 CHEMBL
Aldose reductase Enzyme IC50 6.46 CHEMBL
Arachidonate 15-lipoxygenase Enzyme IC50 6.57 CHEMBL
Carbonic anhydrase Enzyme Ki 5.03 CHEMBL
Leukotriene C4 synthase Unclassified IC50 5.57 CHEMBL

External reference:

IDSource
28F9E0DJY6 UNII
D01959 KEGG_DRUG
4018527 VUID
N0000146849 NUI
4018527 VANDF
C0039294 UMLSCUI
CHEMBL506247 ChEMBL_ID
16129778 PUBCHEM_CID
DB09372 DRUGBANK_ID
C000726650 MESH_SUPPLEMENTAL_RECORD_UI
4319 IUPHAR_LIGAND_ID
10328 RXNORM
7800 MMSL
80867 MMSL
NOCODE MMSL
001938 NDDF
41412001 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Nitrotan HUMAN OTC DRUG LABEL 4 11960-0049 AEROSOL, SPRAY 0.02 g TOPICAL OTC monograph not final 9 sections