dibotermin alfa 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
bone morphogenic proteins 5024 246539-15-1

Description:

MoleculeDescription

Synonyms:

  • dibotermin alfa
  • inductos
  • rhBMP-2
  • recombinant human Bone Morphogenetic Protein-2
a member of the TGF-beta superfamily and closely related to the osteogenic/bone morphogenetic proteins
  • Molecular weight: 25795.62
  • Formula: C1142H1758N320O328S18
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 10367
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Sept. 9, 2002 EMA Medtronic BioPharma B.V.

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M05BC01 MUSCULO-SKELETAL SYSTEM
DRUGS FOR TREATMENT OF BONE DISEASES
DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
Bone morphogenetic proteins

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Fracture of tibia indication 31978002
Degeneration of intervertebral disc indication 77547008




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEMBL2109171 ChEMBL_ID
C499469 MESH_SUPPLEMENTAL_RECORD_UI
DB11639 DRUGBANK_ID
011701 NDDF
408090006 SNOMEDCT_US
421944000 SNOMEDCT_US
C1445578 UMLSCUI
8107 INN_ID
T472P45MG6 UNII

Pharmaceutical products:

None