pancreozymin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4945 9011-97-6

Description:

MoleculeDescription

Synonyms:

  • pancreozymin
  • cholecystokinin
  • CCK
  • pankreozymin
  • CCK-PZ
  • uropancreozymin
  • cholecystokinin 33
  • CCK-33
A peptide, of about 33 amino acids, secreted by the upper INTESTINAL MUCOSA and also found in the central nervous system. It causes gallbladder contraction, release of pancreatic exocrine (or digestive) enzymes, and affects other gastrointestinal functions. Cholecystokinin may be the mediator of satiety.
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V04CK02 VARIOUS
DIAGNOSTIC AGENTS
OTHER DIAGNOSTIC AGENTS
Tests for pancreatic function
MeSH PA D002756 Cholagogues and Choleretics
MeSH PA D005765 Gastrointestinal Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Pancreatic function test indication 252243002




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Cholecystokinin receptor type A GPCR EC50 10 CHEMBL
Gastrin/cholecystokinin type B receptor GPCR AGONIST IC50 8.80 IUPHAR
Cholecystokinin receptor type A GPCR AGONIST Kd 9.30 IUPHAR
Gastrin/cholecystokinin type B receptor GPCR Ki 9.39 CHEMBL
Gastrin/cholecystokinin type B receptor GPCR IC50 9.52 CHEMBL
Cholecystokinin receptor type A GPCR Ki 9.55 CHEMBL

External reference:

IDSource
N0000007750 NUI
C0008328 UMLSCUI
CHEBI:80345 CHEBI
CHEMBL1121 ChEMBL_ID
CHEMBL2108550 ChEMBL_ID
DB08862 DRUGBANK_ID
2420 RXNORM
001219 NDDF
25085002 SNOMEDCT_US
46225008 SNOMEDCT_US
D002766 MESH_DESCRIPTOR_UI
16129670 PUBCHEM_CID
3550 IUPHAR_LIGAND_ID

Pharmaceutical products:

None