Stem definition | Drug id | CAS RN |
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4945 | 9011-97-6 |
Molecule | Description |
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Synonyms:
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A peptide, of about 33 amino acids, secreted by the upper INTESTINAL MUCOSA and also found in the central nervous system. It causes gallbladder contraction, release of pancreatic exocrine (or digestive) enzymes, and affects other gastrointestinal functions. Cholecystokinin may be the mediator of satiety.
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Source | Code | Description |
---|---|---|
ATC | V04CK02 | VARIOUS DIAGNOSTIC AGENTS OTHER DIAGNOSTIC AGENTS Tests for pancreatic function |
MeSH PA | D002756 | Cholagogues and Choleretics |
MeSH PA | D005765 | Gastrointestinal Agents |
Disease | Relation | SNOMED_ID | DOID |
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Pancreatic function test | indication | 252243002 |
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Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Cholecystokinin receptor type A | GPCR | EC50 | 10 | CHEMBL | |||||
Gastrin/cholecystokinin type B receptor | GPCR | AGONIST | IC50 | 8.80 | IUPHAR | ||||
Cholecystokinin receptor type A | GPCR | AGONIST | Kd | 9.30 | IUPHAR | ||||
Gastrin/cholecystokinin type B receptor | GPCR | Ki | 9.39 | CHEMBL | |||||
Gastrin/cholecystokinin type B receptor | GPCR | IC50 | 9.52 | CHEMBL | |||||
Cholecystokinin receptor type A | GPCR | Ki | 9.55 | CHEMBL |
ID | Source |
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N0000007750 | NUI |
C0008328 | UMLSCUI |
CHEBI:80345 | CHEBI |
CHEMBL1121 | ChEMBL_ID |
CHEMBL2108550 | ChEMBL_ID |
DB08862 | DRUGBANK_ID |
2420 | RXNORM |
001219 | NDDF |
25085002 | SNOMEDCT_US |
46225008 | SNOMEDCT_US |
D002766 | MESH_DESCRIPTOR_UI |
16129670 | PUBCHEM_CID |
3550 | IUPHAR_LIGAND_ID |
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