magaldrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
antacids, aluminium salts	4926	74978-16-8

Description:

Molecule

Description

Synonyms:

magnesium aluminate hydrate
moalium hydrate
magaldrate
magaldrate hydrate
anhydrous magaldrate
magaldrate anhydrous
aluminum magnesium hydroxide sulfate
riopan
AY-5710
monalium hydrate

composed of aluminium and magnesium hydroxides and sulphates, used as an antacid

Molecular weight:
Formula: Al5H31Mg10O39S2(H2O)n
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Lymphatic fistula	76.19	57.82	13	1095	773	63487141
Wound infection pseudomonas	75.76	57.82	14	1094	1314	63486600
Femoral hernia incarcerated	75.32	57.82	13	1095	828	63487086
Pancreatic steatosis	72.86	57.82	13	1095	1003	63486911
Arterial haemorrhage	72.17	57.82	14	1094	1703	63486211
Haemarthrosis	63.65	57.82	14	1094	3147	63484767
Seroma	63.25	57.82	13	1095	2118	63485796
Aortic valve stenosis	63.06	57.82	14	1094	3285	63484629
Tachyarrhythmia	58.89	57.82	14	1094	4436	63483478

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Labelled drug-drug interaction medication error	52.76	43.13	15	380	14924	34941612

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Lymphatic fistula	74.59	44.28	13	1526	790	79742059
Femoral hernia incarcerated	73.97	44.28	13	1526	829	79742020
Wound infection pseudomonas	71.55	44.28	14	1525	1607	79741242
Pancreatic steatosis	69.98	44.28	13	1526	1132	79741717
Arterial haemorrhage	65.16	44.28	14	1525	2547	79740302
Seroma	60.94	44.28	13	1526	2287	79740562
Aortic valve stenosis	55.05	44.28	14	1525	5280	79737569
Haemarthrosis	53.75	44.28	14	1525	5798	79737051
Tachyarrhythmia	51.25	44.28	14	1525	6948	79735901
Hepatic cyst	48.35	44.28	13	1526	6076	79736773
Diverticulum intestinal	48.31	44.28	14	1525	8591	79734258
Wound dehiscence	47.32	44.28	13	1526	6582	79736267
Eructation	45.03	44.28	14	1525	10895	79731954

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A02AD02	ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS ANTACIDS Combinations and complexes of aluminium, calcium and magnesium compounds
ATC	A02AF01	ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS ANTACIDS Antacids with antiflatulents
MeSH PA	D000863	Antacids
MeSH PA	D005765	Gastrointestinal Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
D04832	KEGG_DRUG
4019589	VUID
N0000147685	NUI
4019589	VANDF
CHEMBL3833350	ChEMBL_ID
CHEMBL3833408	ChEMBL_ID
C016545	MESH_SUPPLEMENTAL_RECORD_UI
1344-82-7	SECONDARY_CAS_RN
DB08938	DRUGBANK_ID
1872036	RXNORM
5004	MMSL
5823	MMSL
7693	MMSL
d00984	MMSL
001127	NDDF
387240004	SNOMEDCT_US
43343000	SNOMEDCT_US
C0065512	UMLSCUI
4416	INN_ID
122706784	PUBCHEM_CID
6V88E24N5T	UNII

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Zantanol Tab.	HUMAN OTC DRUG LABEL	2	58354-101	TABLET	50 mg	ORAL	OTC monograph final	8 sections
Zantanol Tab.	HUMAN OTC DRUG LABEL	2	58354-120	TABLET	100 mg	ORAL	OTC monograph final	8 sections