carbazochrome indications/contra

Stem definitionDrug idCAS RN
491 69-81-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • carbazochrome
  • adrenochrome monosemicarbazone
  • adrenostazin
  • carbazochrom
  • carbazochrome salicylate
a hemostatic which increases capillary resistance & activates platelet factors, Note: Adona is a multimeaning tradename
  • Molecular weight: 236.23
  • Formula: C10H12N4O3
  • CLOGP: 0.53
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 108.02
  • ALOGS: -1.91
  • ROTB: 1

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC B02BX02 BLOOD AND BLOOD FORMING ORGANS
ANTIHEMORRHAGICS
VITAMIN K AND OTHER HEMOSTATICS
Other systemic hemostatics
MeSH PA D003029 Coagulants
MeSH PA D006401 Hematologic Agents
MeSH PA D006490 Hemostatics

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.86 acidic
pKa2 2.34 Basic
pKa3 1.41 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0006972 UMLSCUI
D01864 KEGG_DRUG
3H4OD401LF UNII
263 INN_ID
13051-01-9 SECONDARY_CAS_RN
004780 NDDF
2011 RXNORM
703411008 SNOMEDCT_US
704671001 SNOMEDCT_US
5353473 PUBCHEM_CID
CHEBI:31349 CHEBI
C073338 MESH_SUPPLEMENTAL_RECORD_UI
DB09012 DRUGBANK_ID
CHEMBL2051960 ChEMBL_ID

Pharmaceutical products:

None