caramiphen indications/contra

Stem definitionDrug idCAS RN
486 77-22-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • caramiphen edisilate
  • caramiphen hydrochloride
  • caramiphen
  • caraminphen
  • caramiphen HCl
  • Molecular weight: 289.42
  • Formula: C18H27NO2
  • CLOGP: 4.64
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 0
  • TPSA: 29.54
  • ALOGS: -3.82
  • ROTB: 8

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.51 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

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TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Lysosomal Pro-X carboxypeptidase Enzyme Ki 7.59 CHEMBL
Sigma non-opioid intracellular receptor 1 Membrane receptor Ki 7.81 CHEMBL
Sodium-dependent dopamine transporter Transporter Ki 5.29 CHEMBL
Muscarinic acetylcholine receptor M2 GPCR Ki 7.50 CHEMBL
Muscarinic acetylcholine receptor M1 GPCR Ki 8.92 CHEMBL

External reference:

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IDSource
4019653 VUID
N0000179066 NUI
C0054635 UMLSCUI
4858SN190E UNII
125-85-9 SECONDARY_CAS_RN
CHEMBL61946 ChEMBL_ID
6472 PUBCHEM_CID
4019653 VANDF
N0000179066 NDFRT
N0000147745 NDFRT
d03571 MMSL
20191 RXNORM
412472003 SNOMEDCT_US
412473008 SNOMEDCT_US
001658 NDDF
1268 INN_ID
CHEBI:135204 CHEBI
CHEMBL1598472 ChEMBL_ID
C004519 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None