captodiame indications/contra

Stem definitionDrug idCAS RN
483 486-17-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • captodiamine hydrochloride
  • captodiame
  • captodiam
  • captodiamin
  • captodiamine
  • captodramin
  • captodramine
  • captodiamine HCl
Captodiamine represents an interesting strategy for achieving benzodiazepine substitution with a low risk of dependence or impairment of cognitive function
  • Molecular weight: 359.59
  • Formula: C21H29NS2
  • CLOGP: 6.40
  • LIPINSKI: 1
  • HAC: 1
  • HDO: 0
  • TPSA: 3.24
  • ALOGS: -6.78
  • ROTB: 10

Drug dosage:

DoseUnitRoute
0.20 g O

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC N05BB02 NERVOUS SYSTEM
PSYCHOLEPTICS
ANXIOLYTICS
Diphenylmethane derivatives

Drug Use (View source of the data)

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DiseaseRelationSNOMED_IDDOID
Anxiety disorder indication 197480006 DOID:2030

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.14 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0771426 UMLSCUI
D07316 KEGG_DRUG
005298 NDDF
4025009 SNOMEDCT_US
89812 RXNORM
10240 PUBCHEM_CID
C495502 MESH_SUPPLEMENTAL_RECORD_UI
DB09014 DRUGBANK_ID
CHEMBL2106143 ChEMBL_ID
CHEMBL2110809 ChEMBL_ID
H93K9455DD UNII
625 INN_ID
CHEBI:135521 CHEBI

Pharmaceutical products:

None