ethyl hydroxybenzoate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4773 | 120-47-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | D01AE10 | DERMATOLOGICALS ANTIFUNGALS FOR DERMATOLOGICAL USE ANTIFUNGALS FOR TOPICAL USE Other antifungals for topical use |
| FDA CS | M0000728 | Allergens |
| FDA PE | N0000175629 | Increased Histamine Release |
| FDA PE | N0000184306 | Cell-mediated Immunity |
| FDA EPC | N0000185508 | Standardized Chemical Allergen |
| CHEBI has role | CHEBI:35718 | antifungal agents |
| CHEBI has role | CHEBI:65256 | antimicrobial food preservatives |
| CHEBI has role | CHEBI:76924 | plant metabolites |
| CHEBI has role | CHEBI:76989 | phytoestrogens |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.39 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Carbonic anhydrase 2 | Enzyme | Ki | 5.32 | CHEMBL | |||||
| Estrogen receptor | Nuclear hormone receptor | EC50 | 4.42 | CHEMBL | |||||
| Carbonic anhydrase 1 | Enzyme | Ki | 5.10 | CHEMBL | |||||
| Estrogen receptor beta | Nuclear hormone receptor | EC50 | 5.73 | CHEMBL | |||||
| Carbonic anhydrase 9 | Enzyme | Ki | 5.09 | CHEMBL | |||||
| Carbonic anhydrase 12 | Enzyme | Ki | 5.07 | CHEMBL | |||||
| Carbonic anhydrase 7 | Enzyme | Ki | 5.06 | CHEMBL | |||||
| Carbonic anhydrase 14 | Enzyme | Ki | 5.11 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| CHEBI:88839 | CHEBI |
| E4B | PDB_CHEM_ID |
| CHEMBL15841 | ChEMBL_ID |
| DB13628 | DRUGBANK_ID |
| 1362892 | RXNORM |
| NOCODE | MMSL |
| 005164 | NDDF |
| 255864002 | SNOMEDCT_US |
| 411198001 | SNOMEDCT_US |
| C3652694 | UMLSCUI |
| 8434 | PUBCHEM_CID |
| 14255EXE39 | UNII |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Anubis Barcelona | HUMAN OTC DRUG LABEL | 27 | 83021-617 | CONCENTRATE | 0 g | TOPICAL | OTC monograph final | 9 sections |
| Anubis Barcelona | HUMAN OTC DRUG LABEL | 27 | 83021-617 | CONCENTRATE | 0 g | TOPICAL | OTC monograph final | 9 sections |
| Anubis Barcelona Regul OIl | HUMAN OTC DRUG LABEL | 27 | 83021-624 | CONCENTRATE | 0 g | TOPICAL | OTC monograph final | 9 sections |
| Anubis Barcelona Regul OIl | HUMAN OTC DRUG LABEL | 27 | 83021-624 | CONCENTRATE | 0 g | TOPICAL | OTC monograph final | 9 sections |