polaprezinc 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4756 107667-60-7

Description:

MoleculeDescription

Synonyms:

  • polaprezinc
stimulates bone growth
  • Molecular weight: 289.60
  • Formula: C9H12N4O3Zn
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hepatic function abnormal 41.27 35.96 16 777 37126 63451103

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Interstitial lung disease 38.17 31.08 23 917 65259 34890732

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Interstitial lung disease 63.51 28.07 38 1985 112562 79629803
Hepatic function abnormal 61.22 28.07 32 1991 73075 79669290
Decreased appetite 44.86 28.07 49 1974 342369 79399996
Platelet count decreased 42.71 28.07 37 1986 194627 79547738

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000897 Anti-Ulcer Agents
MeSH PA D005765 Gastrointestinal Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Peptic ulcer indication 13200003 DOID:750




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
0WA1B15A1Z UNII
D01611 KEGG_DRUG
C0286382 UMLSCUI
CHEBI:32024 CHEBI
CHEMBL242948 ChEMBL_ID
439224 PUBCHEM_CID
DB09221 DRUGBANK_ID
6917 INN_ID
C061957 MESH_SUPPLEMENTAL_RECORD_UI
2179843 RXNORM
016589 NDDF

Pharmaceutical products:

None