naproxcinod 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
nitrogen monoxide (nitric oxide, NO) donors 4674 163133-43-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • naproxcinod
  • nitronaproxen
  • AZD3582
a nitric oxide-releasing NSAID derivative
  • Molecular weight: 347.37
  • Formula: C18H21NO6
  • CLOGP: 4.16
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 0
  • TPSA: 90.58
  • ALOGS: -6.09
  • ROTB: 10

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M01AE18 MUSCULO-SKELETAL SYSTEM
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Propionic acid derivatives
MeSH PA D002317 Cardiovascular Agents
MeSH PA D020030 Nitric Oxide Donors
CHEBI has role CHEBI:35475 non-steroidal anti-inflammatory agent
CHEBI has role CHEBI:35544 cyclooxygenase inhibitors
CHEBI has role CHEBI:50266 Prodrugs
CHEBI has role CHEBI:50566 nitric oxide generators

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D09568 KEGG_DRUG
CHEBI:76254 CHEBI
CHEMBL2103831 ChEMBL_ID
C111751 MESH_SUPPLEMENTAL_RECORD_UI
C094069 MESH_SUPPLEMENTAL_RECORD_UI
9551 IUPHAR_LIGAND_ID
8673 INN_ID
DB06682 DRUGBANK_ID
V24GR4LI3I UNII
C0673815 UMLSCUI
9884642 PUBCHEM_CID

Pharmaceutical products:

None