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betiatide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| peptides and glycopeptides | 4666 | 103725-47-9 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Betiatide is the active ingredient in several kits for the preparation of radioactive diagnostic agents, including technetium Tc 99m mertiatide. It is used in the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstruction and calculi.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| June 15, 1990 | FDA | CURIUM |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Renal scan abnormal | 71.79 | 63.88 | 6 | 34 | 36 | 110589223 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D007202 | Indicators and Reagents |
| MeSH PA | D019275 | Radiopharmaceuticals |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Diagnosis of congenital and acquired renal abnormalities | indication | ||
| Diagnosis of renal failure | indication |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.25 | acidic |
| pKa2 | 12.46 | acidic |
| pKa3 | 12.9 | acidic |
| pKa4 | 13.53 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D03105 | KEGG_DRUG |
| 4039908 | VANDF |
| CHEBI:136015 | CHEBI |
| CHEMBL2109104 | ChEMBL_ID |
| 6176 | INN_ID |
| DB14082 | DRUGBANK_ID |
| 9NV2SR34P8 | UNII |
| 194098 | RXNORM |
| 35599 | MMSL |
| d09061 | MMSL |
| C0672188 | UMLSCUI |
| CHEMBL2107488 | ChEMBL_ID |
| 185457 | PUBCHEM_CID |
| 712599009 | SNOMEDCT_US |
| D017263 | MESH_DESCRIPTOR_UI |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Kit for the Preparation of Technetium Tc99m Mertiatide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45567-0655 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 1 mg | INTRAVENOUS | ANDA | 17 sections |
| TECHNETIUM Tc 99m MERTIATIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65174-261 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 1 mg | INTRAVENOUS | NDA | 23 sections |
| Technescan MAG3 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 69945-096 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 1 mg | INTRAVENOUS | NDA | 17 sections |