DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
dodecanoic acid 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
4642
143-07-7
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
dodecanoic acid
lauric acid
laurostearic acid
vulvic acid
Molecular weight: 200.32
Formula: C12H24O2
CLOGP: 5.10
LIPINSKI: 1
HAC: 2
HDO: 1
TPSA: 37.30
ALOGS: -4.30
ROTB: 10
Drug dosage:
None
ADMET properties:
None
Approvals:
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Agency
Company
Orphan
None
FDA
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FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
CHEBI has role
CHEBI:33282
bactericides
CHEBI has role
CHEBI:76924
plant metabolites
CHEBI has role
CHEBI:84735
algal metabolites
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
4.76
acidic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Peroxisome proliferator-activated receptor alpha
Nuclear hormone receptor
Q07869
PPARA_HUMAN
IC50
4.52
CHEMBL
Peroxisome proliferator-activated receptor gamma
Nuclear hormone receptor
P37231
PPARG_HUMAN
IC50
4.52
CHEMBL
Peroxisome proliferator-activated receptor delta
Nuclear hormone receptor
Q03181
PPARD_HUMAN
IC50
4.52
CHEMBL
Free fatty acid receptor 1
GPCR
O14842
FFAR1_HUMAN
EC50
6.12
CHEMBL
G-protein coupled receptor 84
GPCR
Q9NQS5
GPR84_HUMAN
AGONIST
EC50
5.05
IUPHAR
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External reference:
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entries
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ID
Source
LAU
PDB_CHEM_ID
006214
NDDF
1160N9NU9U
UNII
1363435
RXNORM
3893
PUBCHEM_CID
5534
IUPHAR_LIGAND_ID
C0023139
UMLSCUI
C030358
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:30805
CHEBI
CHEMBL108766
ChEMBL_ID
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
Vitafol Plus
HUMAN PRESCRIPTION DRUG LABEL
17
0642-0092
CAPSULE, LIQUID FILLED
60 mg
ORAL
UNAPPROVED DRUG OTHER
13 sections
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dodecanoic acid