Choline C-11 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4635 94793-58-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • Choline C 11
  • Choline C 11 Injection
  • Choline C11
  • Choline C-11
  • Molecular weight: 103.17
  • Formula: C5H14NO
  • CLOGP: -4.36
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 20.23
  • ALOGS: -1.59
  • ROTB: 2

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Sept. 12, 2012 FDA MCPRF

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000000205 Radiopharmaceutical Activity
FDA EPC N0000177914 Radioactive Diagnostic Agent
CHEBI has role CHEBI:35207 radioactive tracer

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
High affinity choline transporter 1 Transporter Ki 6.17 CHEMBL

External reference:

IDSource
CHEBI:72322 CHEBI
CHEMBL2095207 ChEMBL_ID
DB09277 DRUGBANK_ID
DB09563 DRUGBANK_ID
M4AS4XGD4Q UNII
1425419 RXNORM
725525002 SNOMEDCT_US
C2698585 UMLSCUI
449688 PUBCHEM_CID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Choline C 11 HUMAN PRESCRIPTION DRUG LABEL 1 52670-556 INJECTION 33.10 mCi INTRAVENOUS NDA 25 sections
Choline C 11 HUMAN PRESCRIPTION DRUG LABEL 1 52670-556 INJECTION 33.10 mCi INTRAVENOUS NDA 25 sections
Choline C 11 HUMAN PRESCRIPTION DRUG LABEL 1 60215-111 INJECTION 100 mCi INTRAVENOUS ANDA 16 sections
MIC B12 HUMAN PRESCRIPTION DRUG LABEL 4 70104-806 INJECTION 1 mg INTRAMUSCULAR unapproved drug other 1 sections
Choline C 11 HUMAN PRESCRIPTION DRUG LABEL 1 73410-004 INJECTION 4 mCi INTRAVENOUS ANDA 24 sections
Choline C 11 HUMAN PRESCRIPTION DRUG LABEL 1 75913-311 INJECTION 33.10 mCi INTRAVENOUS ANDA 25 sections