linolenic acid indications/contra

Stem definitionDrug idCAS RN
4618 463-40-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • linolenic acid
  • alpha-Linolenic acid
  • linolenate
A fatty acid that is found in plants and involved in the formation of prostaglandins.
  • Molecular weight: 278.43
  • Formula: C18H30O2
  • CLOGP: 6.82
  • LIPINSKI: 1
  • HAC: 2
  • HDO: 1
  • TPSA: 37.30
  • ALOGS: -6.02
  • RINGS: 0
  • ROTB: 13

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Bioactivity Summary:

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TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Fatty acid-binding protein, heart Cytosolic other Kd 8.56 CHEMBL
Aromatase Enzyme IC50 4.35 CHEMBL
Prostaglandin G/H synthase 1 Enzyme Ki 5.40 CHEMBL
Peroxisome proliferator-activated receptor gamma Nuclear hormone receptor Kd 5.70 CHEMBL
Peroxisome proliferator-activated receptor alpha Nuclear hormone receptor Kd 8.10 CHEMBL
Peroxisome proliferator-activated receptor delta Nuclear hormone receptor IC50 4.80 CHEMBL
Tissue factor Membrane receptor IC50 4.52 CHEMBL
Prostaglandin G/H synthase 2 Enzyme IC50 4.92 CHEMBL
Prostaglandin G/H synthase 1 Enzyme IC50 4.03 CHEMBL

External reference:

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IDSource
N0000006751 NDFRT
81868000 SNOMEDCT_US
DB00132 DRUGBANK_ID
D017962 MESH_DESCRIPTOR_UI
0RBV727H71 UNII
LNL PDB_CHEM_ID
5280934 PUBCHEM_CID
CHEMBL8739 ChEMBL_ID
N0000148143 NUI
C0125903 UMLSCUI
4020239 VUID

Pharmaceutical products:

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ProductCategoryIngredientsNDCFormQuantityRoute MarketingLabel
UltimateCare HUMAN PRESCRIPTION DRUG LABEL 17 13811-050 CAPSULE 50 mg ORAL Unapproved drug other 10 sections
Folcaps Care One HUMAN PRESCRIPTION DRUG LABEL 16 68308-167 CAPSULE, GELATIN COATED 50 mg ORAL UNAPPROVED DRUG OTHER 11 sections
Folcaps Omega-3 HUMAN PRESCRIPTION DRUG LABEL 10 68308-269 CAPSULE, GELATIN COATED 30 mg ORAL UNAPPROVED DRUG OTHER 11 sections
HemeNatal OB plus DHA HUMAN PRESCRIPTION DRUG LABEL 16 76331-904 KIT 0.50 mg None unapproved drug other 8 sections