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lycopene 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4617 | 502-65-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A carotenoid and red pigment produced by tomatoes, other red fruits and vegetables, and photosynthetic algae. It is a key intermediate in the biosynthesis of other carotenoids, and has antioxidant, anti-carcinogenic, radioprotective, and anti-inflammatory properties.
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,ERBB2,GRK2,GSK3B,ITK,MAP2K6,MAP3K7,MAPK10,MAPK7,PDK1,PDK2,PDK4,PRKDC,SIK2,STK33,SYK,TEK,TTK | 29 | |||
| kinase-selectivity-class | AXL,CDK4,GRK2,MAP2K6,STK33,TEK | 6 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D000970 | Antineoplastic Agents |
| MeSH PA | D000975 | Antioxidants |
| MeSH PA | D011837 | Radiation-Protective Agents |
| MeSH PA | D016588 | Anticarcinogenic Agents |
| MeSH PA | D020011 | Protective Agents |
| CHEBI has role | CHEBI:22586 | antioxidant |
| CHEBI has role | CHEBI:33282 | antibacterial agent |
| CHEBI has role | CHEBI:35554 | cardiovascular drug |
| CHEBI has role | CHEBI:35610 | antineoplastic agent |
| CHEBI has role | CHEBI:76924 | plant metabolite |
| CHEBI has role | CHEBI:145947 | antiatherosclerotic agent |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4021425 | VUID |
| N0000148836 | NUI |
| 4021425 | VANDF |
| CHEBI:15948 | CHEBI |
| LYC | PDB_CHEM_ID |
| CHEMBL501174 | ChEMBL_ID |
| DB11231 | DRUGBANK_ID |
| SB0N2N0WV6 | UNII |
| 29008 | RXNORM |
| 009145 | NDDF |
| C0065331 | UMLSCUI |
| D000077276 | MESH_DESCRIPTOR_UI |
| 446925 | PUBCHEM_CID |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| IQQU Advanced Sunscreen SPF 50 | HUMAN OTC DRUG LABEL | 6 | 50403-050 | LOTION | 0.30 g | TOPICAL | OTC MONOGRAPH NOT FINAL | 9 sections |