aceglatone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
45 642-83-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • aceglatone
  • glucaron
  • Molecular weight: 258.18
  • Formula: C10H10O8
  • CLOGP: -1.03
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 0
  • TPSA: 105.20
  • ALOGS: -0.67
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT2,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,CHEK1,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FGFR1,FLT3,GRK2,GRK3,GSK3B,IGF1R,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,KIT,MAP2K6,MAP3K14,MAP3K21,MAP3K7,MAPK1,MAPK12,MAPK7,MAPK8,MAPK9,MAPKAPK2,MARK4,MET,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CD,PIM2,PLK1,PLK2,PLK3,PLK4,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1,ZAP70 70
kinase-selectivity-class AXL,BRAF,CDK16,CDK4,CDK9,DYRK1B,EPHB4,GRK2,JAK2,MAP2K6,MAP3K14,MAPK7,STK33,SYK,TEK,TGFBR1,ZAP70 17
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01805 KEGG_DRUG
C0050406 UMLSCUI
CHEBI:31160 CHEBI
CHEMBL446209 ChEMBL_ID
C038936 MESH_SUPPLEMENTAL_RECORD_UI
636372 PUBCHEM_CID
3151 INN_ID
347Q3OOJ13 UNII
347Q3OOJ13 INXIGHT DRUGS

Pharmaceutical products:

None