Explore drug properties, targets, and indications with answers grounded in DrugCentral.
Powered by DrugCentral + retrieval-augmented AIAsk in your own words. Each question is answered independently.
Select a question to fill the editor, then ask it or make it your own.
Your answer will appear here. Open linked drug cards in a new tab to explore the source details.
Ask DrugCentral helps you explore drug properties, biological targets, and indications using natural language. Sample questions offer starting points, and linked drug cards let you check the underlying records.
Each request is independent; previous questions are not sent as conversation history. You can edit a sample before submitting, retry a failed request, or switch back to normal search. Drug links open in a new tab so your question and answer stay available.
Answers may contain mistakes or omit information. Verify details against DrugCentral records and original sources.
AI can make mistakes. Verify answers against the original sources before relying on them.
| Stem definition | Drug id | CAS RN |
|---|---|---|
| corticosteroids, except prednisolone derivatives | 4456 | 125-04-2 |
None
| Property | Value | Reference |
|---|---|---|
| S (Water solubility) | 0.23 mg/mL | Bocci G, Oprea TI, Benet LZ |
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| mdck-mdr1-bcrp-efflux | MDCK-MDR1-BCRP efflux ratio | 0.933 | Moderate | 0.70 | |
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 | |||
| rat-kpuu-brain | Rat brain Kpuu | 0.010 | % | Moderate | 0.70 |
| Date | Agency | Company | Orphan |
|---|---|---|---|
| April 27, 1955 | FDA | PHARMACIA AND UPJOHN |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Infusion related reaction | 253.16 | 14.91 | 763 | 64157 | 416017 | 90147510 |
| Rheumatic fever | 221.42 | 14.91 | 395 | 64525 | 152726 | 90410801 |
| Dislocation of vertebra | 219.19 | 14.91 | 234 | 64686 | 55734 | 90507793 |
| Drug ineffective | 215.09 | 14.91 | 418 | 64502 | 1383880 | 89179647 |
| Sciatica | 205.72 | 14.91 | 305 | 64615 | 101077 | 90462450 |
| Wound infection | 200.15 | 14.91 | 309 | 64611 | 106093 | 90457434 |
| Joint range of motion decreased | 194.91 | 14.91 | 349 | 64571 | 135294 | 90428233 |
| Adjustment disorder with depressed mood | 194.07 | 14.91 | 221 | 64699 | 56532 | 90506995 |
| Type 2 diabetes mellitus | 192.89 | 14.91 | 440 | 64480 | 202804 | 90360723 |
| Swollen joint count increased | 191.30 | 14.91 | 310 | 64610 | 110896 | 90452631 |
| Toxicity to various agents | 182.91 | 14.91 | 5 | 64915 | 287841 | 90275686 |
| Retinitis | 179.98 | 14.91 | 177 | 64743 | 38281 | 90525246 |
| Injury | 178.21 | 14.91 | 419 | 64501 | 196930 | 90366597 |
| Lupus-like syndrome | 176.91 | 14.91 | 196 | 64724 | 48650 | 90514877 |
| X-ray abnormal | 167.50 | 14.91 | 184 | 64736 | 45240 | 90518287 |
| Joint dislocation | 165.10 | 14.91 | 181 | 64739 | 44401 | 90519126 |
| Road traffic accident | 161.13 | 14.91 | 282 | 64638 | 107344 | 90456183 |
| Porphyria acute | 160.82 | 14.91 | 120 | 64800 | 17855 | 90545672 |
| Deep vein thrombosis postoperative | 159.66 | 14.91 | 224 | 64696 | 70585 | 90492942 |
| Facet joint syndrome | 156.74 | 14.91 | 265 | 64655 | 98124 | 90465403 |
| Impaired healing | 155.51 | 14.91 | 443 | 64477 | 233756 | 90329771 |
| Lower limb fracture | 153.05 | 14.91 | 242 | 64678 | 84771 | 90478756 |
| Walking aid user | 150.70 | 14.91 | 155 | 64765 | 35351 | 90528176 |
| Helicobacter infection | 150.51 | 14.91 | 429 | 64491 | 226421 | 90337106 |
| Grip strength decreased | 145.69 | 14.91 | 248 | 64672 | 92328 | 90471199 |
| Sleep disorder due to general medical condition, insomnia type | 145.33 | 14.91 | 299 | 64621 | 128395 | 90435132 |
| Fibromyalgia | 144.61 | 14.91 | 398 | 64522 | 205871 | 90357656 |
| Hypercholesterolaemia | 144.13 | 14.91 | 259 | 64661 | 100633 | 90462894 |
| Wheezing | 140.59 | 14.91 | 432 | 64488 | 237648 | 90325879 |
| Psoriatic arthropathy | 140.15 | 14.91 | 420 | 64500 | 227915 | 90335612 |
| Drug interaction | 137.12 | 14.91 | 18 | 64902 | 276435 | 90287092 |
| Urticaria | 135.87 | 14.91 | 512 | 64408 | 312222 | 90251305 |
| Prescribed underdose | 132.89 | 14.91 | 212 | 64708 | 74807 | 90488720 |
| Liver disorder | 132.53 | 14.91 | 278 | 64642 | 120991 | 90442536 |
| Fall | 130.67 | 14.91 | 93 | 64827 | 481717 | 90081810 |
| Lupus vulgaris | 130.14 | 14.91 | 161 | 64759 | 44898 | 90518629 |
| Delirium | 129.23 | 14.91 | 252 | 64668 | 104107 | 90459420 |
| Rheumatoid factor positive | 125.08 | 14.91 | 336 | 64584 | 171314 | 90392213 |
| Hepatic cirrhosis | 124.98 | 14.91 | 188 | 64732 | 63065 | 90500462 |
| Irritable bowel syndrome | 123.92 | 14.91 | 378 | 64542 | 207070 | 90356457 |
| Autoimmune disorder | 121.28 | 14.91 | 206 | 64714 | 76538 | 90486989 |
| Exostosis | 121.12 | 14.91 | 169 | 64751 | 52965 | 90510562 |
| Laryngitis | 118.04 | 14.91 | 163 | 64757 | 50590 | 90512937 |
| Lip dry | 118.04 | 14.91 | 238 | 64682 | 100717 | 90462810 |
| Folliculitis | 113.41 | 14.91 | 363 | 64557 | 203990 | 90359537 |
| Seronegative arthritis | 112.62 | 14.91 | 98 | 64822 | 18136 | 90545391 |
| Wound | 109.14 | 14.91 | 468 | 64452 | 302512 | 90261015 |
| Duodenal ulcer perforation | 104.20 | 14.91 | 372 | 64548 | 220916 | 90342611 |
| Foot deformity | 102.12 | 14.91 | 166 | 64754 | 59485 | 90504042 |
| Hand deformity | 101.56 | 14.91 | 451 | 64469 | 295911 | 90267616 |
| C-reactive protein abnormal | 98.45 | 14.91 | 255 | 64665 | 127174 | 90436353 |
| Bone erosion | 98.27 | 14.91 | 153 | 64767 | 52868 | 90510659 |
| Anti-cyclic citrullinated peptide antibody | 98.15 | 14.91 | 109 | 64811 | 27112 | 90536415 |
| Acute kidney injury | 96.17 | 14.91 | 55 | 64865 | 320332 | 90243195 |
| Pulmonary fibrosis | 95.58 | 14.91 | 227 | 64693 | 107276 | 90456251 |
| Hip arthroplasty | 94.29 | 14.91 | 184 | 64736 | 76024 | 90487503 |
| C-reactive protein | 93.68 | 14.91 | 114 | 64806 | 31253 | 90532274 |
| Ear infection | 91.90 | 14.91 | 173 | 64747 | 69602 | 90493925 |
| Ill-defined disorder | 91.49 | 14.91 | 316 | 64604 | 184575 | 90378952 |
| Hypoaesthesia | 89.33 | 14.91 | 453 | 64467 | 313757 | 90249770 |
| Muscle injury | 89.23 | 14.91 | 304 | 64616 | 176350 | 90387177 |
| Amnesia | 87.82 | 14.91 | 221 | 64699 | 108284 | 90455243 |
| Joint stiffness | 87.68 | 14.91 | 181 | 64739 | 77861 | 90485666 |
| Oedema | 83.65 | 14.91 | 324 | 64596 | 199971 | 90363556 |
| Prescribed overdose | 83.40 | 14.91 | 203 | 64717 | 97422 | 90466105 |
| Injection site pain | 82.16 | 14.91 | 13 | 64907 | 173686 | 90389841 |
| Disability | 80.32 | 14.91 | 121 | 64799 | 40624 | 90522903 |
| Infection | 79.58 | 14.91 | 487 | 64433 | 361607 | 90201920 |
| Glossodynia | 79.25 | 14.91 | 446 | 64474 | 321333 | 90242194 |
| Frequent bowel movements | 78.53 | 14.91 | 144 | 64776 | 56791 | 90506736 |
| Product dose omission issue | 76.79 | 14.91 | 58 | 64862 | 291629 | 90271898 |
| Inflammation | 75.47 | 14.91 | 290 | 64630 | 178302 | 90385225 |
| Dry mouth | 75.44 | 14.91 | 296 | 64624 | 183763 | 90379764 |
| Osteoporosis | 75.40 | 14.91 | 194 | 64726 | 96337 | 90467190 |
| Breast cancer stage III | 74.71 | 14.91 | 178 | 64742 | 84269 | 90479258 |
| Sleep disorder | 73.64 | 14.91 | 309 | 64611 | 197721 | 90365806 |
| Constipation | 68.51 | 14.91 | 60 | 64860 | 280335 | 90283192 |
| Colitis ulcerative | 67.95 | 14.91 | 140 | 64780 | 60126 | 90503401 |
| Liver injury | 67.23 | 14.91 | 271 | 64649 | 170296 | 90393231 |
| Visual impairment | 67 | 14.91 | 228 | 64692 | 132137 | 90431390 |
| Pericarditis | 66.86 | 14.91 | 375 | 64545 | 269776 | 90293751 |
| Feeling hot | 64.28 | 14.91 | 160 | 64760 | 77848 | 90485679 |
| Night sweats | 63.60 | 14.91 | 220 | 64700 | 128546 | 90434981 |
| Disease progression | 63.18 | 14.91 | 17 | 64903 | 156598 | 90406929 |
| Anaemia | 63.03 | 14.91 | 97 | 64823 | 352705 | 90210822 |
| Death | 62.74 | 14.91 | 147 | 64773 | 456404 | 90107123 |
| Red blood cell sedimentation rate increased | 61.44 | 14.91 | 163 | 64757 | 82432 | 90481095 |
| Gait inability | 61.19 | 14.91 | 237 | 64683 | 146219 | 90417308 |
| Synovitis | 60.53 | 14.91 | 424 | 64496 | 329328 | 90234199 |
| Hypersensitivity | 60.10 | 14.91 | 542 | 64378 | 454135 | 90109392 |
| Peripheral venous disease | 59.79 | 14.91 | 163 | 64757 | 83758 | 90479769 |
| Lung disorder | 59.75 | 14.91 | 239 | 64681 | 149644 | 90413883 |
| Knee arthroplasty | 58.70 | 14.91 | 161 | 64759 | 83021 | 90480506 |
| Somnolence | 57.06 | 14.91 | 40 | 64880 | 209044 | 90354483 |
| Weight increased | 56.66 | 14.91 | 501 | 64419 | 417426 | 90146101 |
| Musculoskeletal stiffness | 56.61 | 14.91 | 385 | 64535 | 296147 | 90267380 |
| Stomatitis | 53.23 | 14.91 | 358 | 64562 | 274340 | 90289187 |
| Hypertension | 50.41 | 14.91 | 525 | 64395 | 457007 | 90106520 |
| Urinary tract infection | 49.95 | 14.91 | 89 | 64831 | 305543 | 90257984 |
| Systemic lupus erythematosus | 49.63 | 14.91 | 435 | 64485 | 361461 | 90202066 |
| Intentional overdose | 49.25 | 14.91 | 5 | 64915 | 93829 | 90469698 |
| Spinal fusion surgery | 49.20 | 14.91 | 52 | 64868 | 12231 | 90551296 |
| Cerebrovascular accident | 48.72 | 14.91 | 14 | 64906 | 123519 | 90440008 |
| Malignant neoplasm progression | 48.32 | 14.91 | 9 | 64911 | 106861 | 90456666 |
| Sinusitis | 47.36 | 14.91 | 413 | 64507 | 342675 | 90220852 |
| Underdose | 46.84 | 14.91 | 113 | 64807 | 53904 | 90509623 |
| Spondylitis | 44.74 | 14.91 | 53 | 64867 | 14125 | 90549402 |
| Osteoarthritis | 44.67 | 14.91 | 266 | 64654 | 195464 | 90368063 |
| Discomfort | 44.17 | 14.91 | 342 | 64578 | 273993 | 90289534 |
| Hepatic enzyme increased | 43.59 | 14.91 | 422 | 64498 | 360314 | 90203213 |
| Neuropathy peripheral | 43.27 | 14.91 | 22 | 64898 | 136948 | 90426579 |
| Maternal exposure timing unspecified | 43.22 | 14.91 | 66 | 64854 | 22417 | 90541110 |
| Pulmonary embolism | 42.86 | 14.91 | 20 | 64900 | 130800 | 90432727 |
| Blood cholesterol increased | 42.03 | 14.91 | 274 | 64646 | 207738 | 90355789 |
| Obesity | 41.84 | 14.91 | 168 | 64752 | 105339 | 90458188 |
| Bursitis | 41.77 | 14.91 | 196 | 64724 | 131458 | 90432069 |
| Sleep disorder due to a general medical condition | 41.40 | 14.91 | 96 | 64824 | 44642 | 90518885 |
| Suicidal ideation | 41.31 | 14.91 | 3 | 64917 | 73852 | 90489675 |
| Chronic obstructive pulmonary disease | 41.30 | 14.91 | 3 | 64917 | 73826 | 90489701 |
| Blister | 41.11 | 14.91 | 318 | 64602 | 254680 | 90308847 |
| Injection site erythema | 41.05 | 14.91 | 10 | 64910 | 98492 | 90465035 |
| Seizure | 40.59 | 14.91 | 30 | 64890 | 152599 | 90410928 |
| Coma | 40.49 | 14.91 | 3 | 64917 | 72629 | 90490898 |
| Drug tolerance decreased | 40.24 | 14.91 | 78 | 64842 | 32052 | 90531475 |
| Balance disorder | 40.18 | 14.91 | 10 | 64910 | 97070 | 90466457 |
| Cough | 40.10 | 14.91 | 133 | 64787 | 368829 | 90194698 |
| Mobility decreased | 40.04 | 14.91 | 312 | 64608 | 250422 | 90313105 |
| Myocardial infarction | 38.27 | 14.91 | 14 | 64906 | 105958 | 90457569 |
| Intentional product use issue | 36.93 | 14.91 | 274 | 64646 | 216618 | 90346909 |
| Dehydration | 35.13 | 14.91 | 53 | 64867 | 194394 | 90369133 |
| Hypotension | 34.87 | 14.91 | 118 | 64802 | 325279 | 90238248 |
| Suicide attempt | 34.84 | 14.91 | 6 | 64914 | 75393 | 90488134 |
| Wrong technique in product usage process | 34.65 | 14.91 | 5 | 64915 | 71566 | 90491961 |
| Medication error | 34.53 | 14.91 | 136 | 64784 | 84516 | 90479011 |
| General physical health deterioration | 34.25 | 14.91 | 397 | 64523 | 354718 | 90208809 |
| Grip strength | 34.22 | 14.91 | 37 | 64883 | 8928 | 90554599 |
| Blood glucose increased | 33.70 | 14.91 | 13 | 64907 | 95233 | 90468294 |
| Nausea | 33.22 | 14.91 | 578 | 64342 | 1109738 | 89453789 |
| Pemphigus | 33.13 | 14.91 | 369 | 64551 | 326495 | 90237032 |
| Influenza | 32.56 | 14.91 | 31 | 64889 | 139233 | 90424294 |
| Weight fluctuation | 32.49 | 14.91 | 54 | 64866 | 19695 | 90543832 |
| Cardiac failure congestive | 30.95 | 14.91 | 16 | 64904 | 98678 | 90464849 |
| Atrial fibrillation | 30.94 | 14.91 | 30 | 64890 | 133581 | 90429946 |
| Mucosal inflammation | 30.43 | 14.91 | 3 | 64917 | 57622 | 90505905 |
| Hyponatraemia | 29.76 | 14.91 | 31 | 64889 | 133507 | 90430020 |
| Haemoglobin decreased | 29.40 | 14.91 | 44 | 64876 | 161912 | 90401615 |
| Cataract | 28.74 | 14.91 | 8 | 64912 | 72084 | 90491443 |
| Influenza like illness | 28.52 | 14.91 | 11 | 64909 | 80600 | 90482927 |
| Contusion | 28.43 | 14.91 | 290 | 64630 | 250926 | 90312601 |
| Swollen joint count | 28.39 | 14.91 | 33 | 64887 | 8620 | 90554907 |
| Fatigue | 28.35 | 14.91 | 621 | 64299 | 1153402 | 89410125 |
| Respiratory disorder | 27.96 | 14.91 | 106 | 64814 | 64710 | 90498817 |
| Musculoskeletal pain | 27.82 | 14.91 | 214 | 64706 | 171037 | 90392490 |
| Upper respiratory tract infection | 27.74 | 14.91 | 172 | 64748 | 128146 | 90435381 |
| Back pain | 27.59 | 14.91 | 125 | 64795 | 317050 | 90246477 |
| Gastrooesophageal reflux disease | 27.55 | 14.91 | 48 | 64872 | 166289 | 90397238 |
| Cardiac arrest | 27.41 | 14.91 | 21 | 64899 | 104914 | 90458613 |
| Bradycardia | 27.18 | 14.91 | 13 | 64907 | 83834 | 90479693 |
| Injection site swelling | 27.13 | 14.91 | 5 | 64915 | 59834 | 90503693 |
| Anti-cyclic citrullinated peptide antibody positive | 26.31 | 14.91 | 272 | 64648 | 236161 | 90327366 |
| Drug-induced liver injury | 26.15 | 14.91 | 131 | 64789 | 90187 | 90473340 |
| Neutropenia | 25.86 | 14.91 | 79 | 64841 | 224825 | 90338702 |
| Rectal haemorrhage | 25.37 | 14.91 | 122 | 64798 | 82622 | 90480905 |
| C-reactive protein increased | 25.32 | 14.91 | 219 | 64701 | 181170 | 90382357 |
| Vision blurred | 25.26 | 14.91 | 25 | 64895 | 110268 | 90453259 |
| Lethargy | 25.18 | 14.91 | 7 | 64913 | 63132 | 90500395 |
| Weight decreased | 24.80 | 14.91 | 396 | 64524 | 379514 | 90184013 |
| Herpes zoster | 24.65 | 14.91 | 19 | 64901 | 94625 | 90468902 |
| Swelling | 24.49 | 14.91 | 429 | 64491 | 418629 | 90144898 |
| Feeling abnormal | 24.44 | 14.91 | 52 | 64868 | 167183 | 90396344 |
| Renal failure | 24.35 | 14.91 | 35 | 64885 | 130972 | 90432555 |
| Syncope | 24.11 | 14.91 | 36 | 64884 | 132627 | 90430900 |
| Cognitive disorder | 23.69 | 14.91 | 10 | 64910 | 69397 | 90494130 |
| Subcutaneous drug absorption impaired | 23.59 | 14.91 | 38 | 64882 | 13507 | 90550020 |
| Cardiac disorder | 23.26 | 14.91 | 6 | 64914 | 56866 | 90506661 |
| Chronic kidney disease | 23.18 | 14.91 | 4 | 64916 | 50187 | 90513340 |
| Oedema peripheral | 22.94 | 14.91 | 284 | 64636 | 257631 | 90305896 |
| Thrombosis | 22.78 | 14.91 | 12 | 64908 | 73239 | 90490288 |
| Insomnia | 22.67 | 14.91 | 350 | 64570 | 333124 | 90230403 |
| Breast cancer stage II | 22.58 | 14.91 | 66 | 64854 | 35268 | 90528259 |
| Injection site bruising | 22.41 | 14.91 | 5 | 64915 | 52302 | 90511225 |
| Vertigo | 22.36 | 14.91 | 11 | 64909 | 69800 | 90493727 |
| Dyspnoea exertional | 22.25 | 14.91 | 12 | 64908 | 72276 | 90491251 |
| Overdose | 22.25 | 14.91 | 50 | 64870 | 157659 | 90405868 |
| Intentional product misuse | 22.07 | 14.91 | 19 | 64901 | 89585 | 90473942 |
| Unevaluable event | 22.02 | 14.91 | 6 | 64914 | 54842 | 90508685 |
| White blood cell count increased | 21.97 | 14.91 | 101 | 64819 | 67140 | 90496387 |
| Hyperhidrosis | 21.97 | 14.91 | 40 | 64880 | 136265 | 90427262 |
| Ascites | 21.62 | 14.91 | 4 | 64916 | 47736 | 90515791 |
| General symptom | 21.36 | 14.91 | 38 | 64882 | 14630 | 90548897 |
| Breast cancer stage I | 21.02 | 14.91 | 30 | 64890 | 9594 | 90553933 |
| Transient ischaemic attack | 20.94 | 14.91 | 3 | 64917 | 43173 | 90520354 |
| Pleural effusion | 20.73 | 14.91 | 30 | 64890 | 111961 | 90451566 |
| Femur fracture | 20.57 | 14.91 | 4 | 64916 | 46078 | 90517449 |
| Myalgia | 20.50 | 14.91 | 61 | 64859 | 175064 | 90388463 |
| Pruritus | 20.43 | 14.91 | 520 | 64400 | 541005 | 90022522 |
| Rheumatoid arthritis | 20.41 | 14.91 | 164 | 64756 | 362450 | 90201077 |
| Diverticulitis | 20.01 | 14.91 | 4 | 64916 | 45183 | 90518344 |
| Muscular weakness | 19.87 | 14.91 | 231 | 64689 | 206435 | 90357092 |
| Renal impairment | 19.75 | 14.91 | 28 | 64892 | 105393 | 90458134 |
| Pain in jaw | 19.74 | 14.91 | 5 | 64915 | 47980 | 90515547 |
| Deep vein thrombosis | 19.60 | 14.91 | 22 | 64898 | 91598 | 90471929 |
| Electrocardiogram QT prolonged | 19.57 | 14.91 | 14 | 64906 | 72442 | 90491085 |
| Dyspepsia | 18.83 | 14.91 | 221 | 64699 | 197939 | 90365588 |
| Pain | 18.81 | 14.91 | 557 | 64363 | 995784 | 89567743 |
| Epistaxis | 18.70 | 14.91 | 20 | 64900 | 85105 | 90478422 |
| Drug reaction with eosinophilia and systemic symptoms | 18.49 | 14.91 | 4 | 64916 | 42754 | 90520773 |
| Osteonecrosis of jaw | 18.31 | 14.91 | 3 | 64917 | 39100 | 90524427 |
| Colitis | 18.26 | 14.91 | 14 | 64906 | 69928 | 90493599 |
| COVID-19 | 18.22 | 14.91 | 61 | 64859 | 168782 | 90394745 |
| Flushing | 18.12 | 14.91 | 117 | 64803 | 88374 | 90475153 |
| Abortion spontaneous | 18.11 | 14.91 | 8 | 64912 | 54048 | 90509479 |
| Adverse event | 18.11 | 14.91 | 145 | 64775 | 117273 | 90446254 |
| Sedation | 18.02 | 14.91 | 6 | 64914 | 48165 | 90515362 |
| Gastrointestinal haemorrhage | 17.89 | 14.91 | 23 | 64897 | 90225 | 90473302 |
| Rash vesicular | 17.89 | 14.91 | 40 | 64880 | 18157 | 90545370 |
| Liver function test abnormal | 17.88 | 14.91 | 7 | 64913 | 50838 | 90512689 |
| External ear cellulitis | 17.81 | 14.91 | 7 | 64913 | 284 | 90563243 |
| Endometritis decidual | 17.65 | 14.91 | 4 | 64916 | 21 | 90563506 |
| Flatulence | 17.63 | 14.91 | 4 | 64916 | 41363 | 90522164 |
| Dysphagia | 17.17 | 14.91 | 34 | 64886 | 112244 | 90451283 |
| Blood creatinine increased | 17.02 | 14.91 | 29 | 64891 | 101357 | 90462170 |
| Hypoglycaemia | 16.97 | 14.91 | 15 | 64905 | 69833 | 90493694 |
| Angioedema | 16.92 | 14.91 | 13 | 64907 | 64863 | 90498664 |
| Dysarthria | 16.83 | 14.91 | 9 | 64911 | 54473 | 90509054 |
| Swollen tongue | 16.71 | 14.91 | 6 | 64914 | 45950 | 90517577 |
| Cholestasis | 16.53 | 14.91 | 3 | 64917 | 36296 | 90527231 |
| Therapy non-responder | 16.51 | 14.91 | 160 | 64760 | 136544 | 90426983 |
| Injection site pruritus | 16.47 | 14.91 | 9 | 64911 | 53825 | 90509702 |
| Breast cancer | 16.43 | 14.91 | 9 | 64911 | 53752 | 90509775 |
| Asthma | 16.38 | 14.91 | 254 | 64666 | 241906 | 90321621 |
| Loss of consciousness | 16.30 | 14.91 | 49 | 64871 | 140189 | 90423338 |
| Hallucination | 16.23 | 14.91 | 14 | 64906 | 65945 | 90497582 |
| Haematoma | 16.20 | 14.91 | 4 | 64916 | 39044 | 90524483 |
| Lactic acidosis | 16.09 | 14.91 | 8 | 64912 | 50455 | 90513072 |
| Skin exfoliation | 16.01 | 14.91 | 15 | 64905 | 67898 | 90495629 |
| Live birth | 15.83 | 14.91 | 104 | 64816 | 79003 | 90484524 |
| Interstitial lung disease | 15.64 | 14.91 | 19 | 64901 | 76386 | 90487141 |
| Polyglandular disorder | 15.64 | 14.91 | 6 | 64914 | 228 | 90563299 |
| Asthenia | 15.51 | 14.91 | 279 | 64641 | 533472 | 90030055 |
| Hypercalcaemia | 15.23 | 14.91 | 3 | 64917 | 34237 | 90529290 |
| Hepatitis | 15.11 | 14.91 | 17 | 64903 | 70722 | 90492805 |
| Rhabdomyolysis | 15.07 | 14.91 | 9 | 64911 | 51247 | 90512280 |
| Depressed level of consciousness | 15.00 | 14.91 | 18 | 64902 | 72766 | 90490761 |
| Foetal exposure during pregnancy | 14.98 | 14.91 | 6 | 64914 | 42969 | 90520558 |
| Myelosuppression | 14.94 | 14.91 | 10 | 64910 | 53581 | 90509946 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Infusion related reaction | 313.13 | 14.88 | 220 | 14949 | 60586 | 42545580 |
| Nipple swelling | 99.40 | 14.88 | 24 | 15145 | 373 | 42605793 |
| Mechanical ventilation complication | 85.76 | 14.88 | 24 | 15145 | 680 | 42605486 |
| Nipple pain | 79.62 | 14.88 | 25 | 15144 | 1062 | 42605104 |
| Anaphylactic reaction | 64.84 | 14.88 | 78 | 15091 | 42665 | 42563501 |
| Anaphylactic shock | 60.80 | 14.88 | 57 | 15112 | 23460 | 42582706 |
| Pyrexia | 60.22 | 14.88 | 288 | 14881 | 393754 | 42212412 |
| Disseminated intravascular coagulation | 56.38 | 14.88 | 56 | 15113 | 24738 | 42581428 |
| Urticaria | 54.63 | 14.88 | 96 | 15073 | 73940 | 42532226 |
| Flushing | 53.60 | 14.88 | 66 | 15103 | 36962 | 42569204 |
| Inspiratory capacity decreased | 48.94 | 14.88 | 23 | 15146 | 2944 | 42603222 |
| Febrile neutropenia | 47.85 | 14.88 | 160 | 15009 | 185543 | 42420623 |
| Haemothorax | 44.41 | 14.88 | 26 | 15143 | 5210 | 42600956 |
| Blood pressure fluctuation | 43.93 | 14.88 | 51 | 15118 | 26857 | 42579309 |
| Adverse reaction | 42.47 | 14.88 | 23 | 15146 | 3970 | 42602196 |
| Polyp | 42.03 | 14.88 | 24 | 15145 | 4590 | 42601576 |
| Blood iron decreased | 39.91 | 14.88 | 26 | 15143 | 6292 | 42599874 |
| Toxicity to various agents | 39.63 | 14.88 | 16 | 15153 | 229120 | 42377046 |
| Angiopathy | 38.63 | 14.88 | 24 | 15145 | 5353 | 42600813 |
| Platelet count decreased | 36.18 | 14.88 | 120 | 15049 | 138461 | 42467705 |
| Blood pressure increased | 32.85 | 14.88 | 95 | 15074 | 101833 | 42504333 |
| Drug interaction | 31.75 | 14.88 | 29 | 15140 | 266970 | 42339196 |
| Face oedema | 31.30 | 14.88 | 31 | 15138 | 13635 | 42592531 |
| Death | 31.04 | 14.88 | 77 | 15092 | 471108 | 42135058 |
| Chills | 30.62 | 14.88 | 88 | 15081 | 93978 | 42512188 |
| Large intestine polyp | 28.96 | 14.88 | 25 | 15144 | 9240 | 42596926 |
| Cerebellar tumour | 27.92 | 14.88 | 7 | 15162 | 128 | 42606038 |
| Enterococcus test positive | 27.60 | 14.88 | 13 | 15156 | 1672 | 42604494 |
| Frequent bowel movements | 27.55 | 14.88 | 36 | 15133 | 21371 | 42584795 |
| Hypersensitivity | 26.82 | 14.88 | 71 | 15098 | 72299 | 42533867 |
| Emphysema | 25.55 | 14.88 | 26 | 15143 | 11809 | 42594357 |
| Neutrophil count decreased | 25.33 | 14.88 | 64 | 15105 | 63351 | 42542815 |
| Myoglobinaemia | 24.92 | 14.88 | 7 | 15162 | 201 | 42605965 |
| Overdose | 24.55 | 14.88 | 4 | 15165 | 105260 | 42500906 |
| Blood pressure decreased | 24.49 | 14.88 | 60 | 15109 | 58272 | 42547894 |
| Septic shock | 24.45 | 14.88 | 80 | 15089 | 91592 | 42514574 |
| Shock haemorrhagic | 23.57 | 14.88 | 29 | 15140 | 16213 | 42589953 |
| Oxygen saturation decreased | 23.50 | 14.88 | 63 | 15106 | 64624 | 42541542 |
| Posthaemorrhagic hydrocephalus | 23.42 | 14.88 | 6 | 15163 | 120 | 42606046 |
| Adrenal insufficiency | 23.08 | 14.88 | 31 | 15138 | 18893 | 42587273 |
| Off label use | 22.68 | 14.88 | 335 | 14834 | 638000 | 41968166 |
| Therapeutic product effect prolonged | 21.99 | 14.88 | 7 | 15162 | 311 | 42605855 |
| Intentional product use issue | 21.27 | 14.88 | 65 | 15104 | 71768 | 42534398 |
| Hypovolaemia | 20.83 | 14.88 | 23 | 15146 | 11462 | 42594704 |
| Pneumothorax | 20.64 | 14.88 | 33 | 15136 | 23510 | 42582656 |
| Middle ear inflammation | 20.50 | 14.88 | 6 | 15163 | 200 | 42605966 |
| Cytomegalovirus infection | 20.16 | 14.88 | 39 | 15130 | 32267 | 42573899 |
| Pituitary tumour recurrent | 19.97 | 14.88 | 5 | 15164 | 91 | 42606075 |
| Abdominal discomfort | 19.46 | 14.88 | 65 | 15104 | 75190 | 42530976 |
| Steroid dependence | 18.74 | 14.88 | 17 | 15152 | 6705 | 42599461 |
| Cytomegalovirus test positive | 18.47 | 14.88 | 14 | 15155 | 4305 | 42601861 |
| White blood cell count decreased | 18.43 | 14.88 | 83 | 15086 | 110313 | 42495853 |
| Antithrombin III decreased | 17.95 | 14.88 | 7 | 15162 | 567 | 42605599 |
| Product use issue | 17.85 | 14.88 | 64 | 15105 | 76687 | 42529479 |
| Engraft failure | 17.84 | 14.88 | 7 | 15162 | 576 | 42605590 |
| Epstein-Barr virus associated lymphoproliferative disorder | 17.79 | 14.88 | 11 | 15158 | 2432 | 42603734 |
| Heart rate irregular | 17.63 | 14.88 | 25 | 15144 | 16025 | 42590141 |
| Herpes dermatitis | 17.62 | 14.88 | 5 | 15164 | 149 | 42606017 |
| Vein rupture | 17.42 | 14.88 | 8 | 15161 | 971 | 42605195 |
| Acute graft versus host disease in skin | 17.30 | 14.88 | 17 | 15152 | 7407 | 42598759 |
| Infection | 17.04 | 14.88 | 82 | 15087 | 111986 | 42494180 |
| Pallor | 16.97 | 14.88 | 34 | 15135 | 28852 | 42577314 |
| Impaired quality of life | 16.95 | 14.88 | 23 | 15146 | 14154 | 42592012 |
| Heart rate decreased | 16.87 | 14.88 | 39 | 15130 | 36493 | 42569673 |
| Anaplastic large cell lymphoma T- and null-cell types recurrent | 16.82 | 14.88 | 4 | 15165 | 58 | 42606108 |
| Chest discomfort | 16.49 | 14.88 | 55 | 15114 | 63561 | 42542605 |
| Hypopnoea | 16.44 | 14.88 | 17 | 15152 | 7865 | 42598301 |
| Catarrh | 16.41 | 14.88 | 15 | 15154 | 5971 | 42600195 |
| Burns second degree | 16.18 | 14.88 | 15 | 15154 | 6081 | 42600085 |
| Sleep disorder due to a general medical condition | 16.04 | 14.88 | 25 | 15144 | 17428 | 42588738 |
| Cytomegalovirus viraemia | 15.82 | 14.88 | 19 | 15150 | 10358 | 42595808 |
| Traumatic shock | 15.81 | 14.88 | 3 | 15166 | 13 | 42606153 |
| Hepatic function abnormal | 15.58 | 14.88 | 47 | 15122 | 51520 | 42554646 |
| Myocardial infarction | 15.28 | 14.88 | 13 | 15156 | 123996 | 42482170 |
| Leukaemia recurrent | 15.08 | 14.88 | 9 | 15160 | 1867 | 42604299 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Infusion related reaction | 328.93 | 13.97 | 711 | 65235 | 380451 | 110142902 |
| Rheumatic fever | 245.56 | 13.97 | 333 | 65613 | 122246 | 110401107 |
| X-ray abnormal | 227.92 | 13.97 | 186 | 65760 | 37931 | 110485422 |
| Toxicity to various agents | 216.55 | 13.97 | 19 | 65927 | 480536 | 110042817 |
| Sleep disorder due to general medical condition, insomnia type | 213.11 | 13.97 | 288 | 65658 | 105355 | 110417998 |
| Facet joint syndrome | 207.65 | 13.97 | 272 | 65674 | 96556 | 110426797 |
| Swollen joint count increased | 196.69 | 13.97 | 246 | 65700 | 83415 | 110439938 |
| Porphyria acute | 190.28 | 13.97 | 126 | 65820 | 18654 | 110504699 |
| Sciatica | 177.44 | 13.97 | 246 | 65700 | 92153 | 110431200 |
| Dislocation of vertebra | 173.10 | 13.97 | 169 | 65777 | 43552 | 110479801 |
| Ill-defined disorder | 172.48 | 13.97 | 324 | 65622 | 156529 | 110366824 |
| Type 2 diabetes mellitus | 171.66 | 13.97 | 347 | 65599 | 176885 | 110346468 |
| Drug interaction | 164.90 | 13.97 | 47 | 65899 | 500136 | 110023217 |
| Psoriatic arthropathy | 164.76 | 13.97 | 363 | 65583 | 196398 | 110326955 |
| Liver disorder | 157.85 | 13.97 | 295 | 65651 | 141948 | 110381405 |
| Lip dry | 156.72 | 13.97 | 242 | 65704 | 99841 | 110423512 |
| Fibromyalgia | 155.36 | 13.97 | 326 | 65620 | 170583 | 110352770 |
| Urticaria | 154.34 | 13.97 | 479 | 65467 | 318378 | 110204975 |
| Injury | 154.06 | 13.97 | 332 | 65614 | 176933 | 110346420 |
| Helicobacter infection | 149.40 | 13.97 | 333 | 65613 | 181544 | 110341809 |
| Adjustment disorder with depressed mood | 147.02 | 13.97 | 155 | 65791 | 43728 | 110479625 |
| Joint range of motion decreased | 139.34 | 13.97 | 256 | 65690 | 121576 | 110401777 |
| C-reactive protein abnormal | 134.06 | 13.97 | 261 | 65685 | 129434 | 110393919 |
| Rheumatoid factor positive | 133.74 | 13.97 | 263 | 65683 | 131377 | 110391976 |
| Impaired healing | 126.90 | 13.97 | 328 | 65618 | 196389 | 110326964 |
| Hand deformity | 126.50 | 13.97 | 350 | 65596 | 218156 | 110305197 |
| Fall | 126.02 | 13.97 | 105 | 65841 | 603377 | 109919976 |
| Frequent bowel movements | 123.68 | 13.97 | 181 | 65765 | 71209 | 110452144 |
| Wound | 123.55 | 13.97 | 363 | 65583 | 234074 | 110289279 |
| Road traffic accident | 123.22 | 13.97 | 226 | 65720 | 107172 | 110416181 |
| Folliculitis | 122.31 | 13.97 | 293 | 65653 | 167360 | 110355993 |
| Lower limb fracture | 119.07 | 13.97 | 183 | 65763 | 75165 | 110448188 |
| Systemic lupus erythematosus | 118.34 | 13.97 | 377 | 65569 | 253961 | 110269392 |
| Irritable bowel syndrome | 117.66 | 13.97 | 285 | 65661 | 163930 | 110359423 |
| Wound infection | 117.05 | 13.97 | 208 | 65738 | 96257 | 110427096 |
| Duodenal ulcer perforation | 116.37 | 13.97 | 298 | 65648 | 177402 | 110345951 |
| Glossodynia | 116.27 | 13.97 | 343 | 65603 | 221661 | 110301692 |
| C-reactive protein | 115.88 | 13.97 | 115 | 65831 | 30216 | 110493137 |
| Retinitis | 115.14 | 13.97 | 118 | 65828 | 32209 | 110491144 |
| Lupus-like syndrome | 113.98 | 13.97 | 131 | 65815 | 40661 | 110482692 |
| Acute kidney injury | 113.57 | 13.97 | 127 | 65819 | 635303 | 109888050 |
| Deep vein thrombosis postoperative | 112.52 | 13.97 | 157 | 65789 | 59134 | 110464219 |
| Death | 102.17 | 13.97 | 162 | 65784 | 698707 | 109824646 |
| Inflammation | 101.59 | 13.97 | 299 | 65647 | 192939 | 110330414 |
| Muscle injury | 101.52 | 13.97 | 245 | 65701 | 140562 | 110382791 |
| Dry mouth | 96.29 | 13.97 | 300 | 65646 | 199648 | 110323705 |
| Infection | 95.98 | 13.97 | 449 | 65497 | 361751 | 110161602 |
| Night sweats | 90.10 | 13.97 | 227 | 65719 | 133756 | 110389597 |
| Wheezing | 89.00 | 13.97 | 344 | 65602 | 254886 | 110268467 |
| Nipple swelling | 87.09 | 13.97 | 24 | 65922 | 373 | 110522980 |
| Hypersensitivity | 86.76 | 13.97 | 472 | 65474 | 403526 | 110119827 |
| Sleep disorder | 82.13 | 13.97 | 283 | 65663 | 198361 | 110324992 |
| Synovitis | 81.75 | 13.97 | 352 | 65594 | 273740 | 110249613 |
| Peripheral venous disease | 80.54 | 13.97 | 164 | 65782 | 83953 | 110439400 |
| Grip strength decreased | 79.97 | 13.97 | 159 | 65787 | 80015 | 110443338 |
| Drug ineffective | 79.74 | 13.97 | 556 | 65390 | 1519984 | 109003369 |
| Feeling hot | 78.36 | 13.97 | 170 | 65776 | 90936 | 110432417 |
| Mechanical ventilation complication | 75.36 | 13.97 | 25 | 65921 | 746 | 110522607 |
| Intentional product use issue | 75.18 | 13.97 | 320 | 65626 | 247586 | 110275767 |
| Autoimmune disorder | 74.08 | 13.97 | 137 | 65809 | 65346 | 110458007 |
| Pericarditis | 72.06 | 13.97 | 290 | 65656 | 218824 | 110304529 |
| Stomatitis | 71.53 | 13.97 | 335 | 65611 | 269907 | 110253446 |
| Colitis ulcerative | 70.73 | 13.97 | 148 | 65798 | 77215 | 110446138 |
| Pemphigus | 69.78 | 13.97 | 283 | 65663 | 214287 | 110309066 |
| Lupus vulgaris | 67.70 | 13.97 | 92 | 65854 | 33791 | 110489562 |
| Lung disorder | 67.14 | 13.97 | 248 | 65698 | 179799 | 110343554 |
| Bursitis | 66.32 | 13.97 | 199 | 65747 | 129719 | 110393634 |
| Sinusitis | 65.93 | 13.97 | 350 | 65596 | 296338 | 110227015 |
| Underdose | 63.33 | 13.97 | 126 | 65820 | 63428 | 110459925 |
| Laryngitis | 62.81 | 13.97 | 100 | 65846 | 42311 | 110481042 |
| Discomfort | 61.90 | 13.97 | 273 | 65673 | 214434 | 110308919 |
| Nipple pain | 61.90 | 13.97 | 24 | 65922 | 1132 | 110522221 |
| Weight increased | 59.97 | 13.97 | 442 | 65504 | 419202 | 110104151 |
| Maternal exposure timing unspecified | 59.57 | 13.97 | 68 | 65878 | 20945 | 110502408 |
| Exostosis | 59.50 | 13.97 | 102 | 65844 | 45854 | 110477499 |
| Liver injury | 59.31 | 13.97 | 211 | 65735 | 150202 | 110373151 |
| Anaemia | 59.15 | 13.97 | 151 | 65795 | 546935 | 109976418 |
| Drug tolerance decreased | 58.43 | 13.97 | 77 | 65869 | 27463 | 110495890 |
| Delirium | 58.10 | 13.97 | 195 | 65751 | 134830 | 110388523 |
| Myocardial infarction | 57.98 | 13.97 | 21 | 65925 | 192062 | 110331291 |
| Swelling | 57.94 | 13.97 | 383 | 65563 | 350658 | 110172695 |
| Intentional overdose | 57.59 | 13.97 | 6 | 65940 | 132495 | 110390858 |
| Obesity | 57.26 | 13.97 | 173 | 65773 | 113178 | 110410175 |
| Pulmonary fibrosis | 56.58 | 13.97 | 161 | 65785 | 101881 | 110421472 |
| Prescribed overdose | 56.39 | 13.97 | 146 | 65800 | 87435 | 110435918 |
| Breast cancer stage III | 56.29 | 13.97 | 137 | 65809 | 78980 | 110444373 |
| Walking aid user | 56.15 | 13.97 | 72 | 65874 | 25003 | 110498350 |
| Injection site pain | 54.48 | 13.97 | 19 | 65927 | 177903 | 110345450 |
| Joint dislocation | 52.54 | 13.97 | 82 | 65864 | 34108 | 110489245 |
| Amnesia | 52.42 | 13.97 | 160 | 65786 | 105248 | 110418105 |
| Oedema | 50.29 | 13.97 | 253 | 65693 | 209723 | 110313630 |
| Musculoskeletal stiffness | 49.66 | 13.97 | 311 | 65635 | 279511 | 110243842 |
| Somnolence | 49.26 | 13.97 | 63 | 65883 | 297386 | 110225967 |
| Hypercholesterolaemia | 49.08 | 13.97 | 142 | 65804 | 90695 | 110432658 |
| Disease progression | 47.78 | 13.97 | 45 | 65901 | 243989 | 110279364 |
| Product dose omission issue | 47.48 | 13.97 | 74 | 65872 | 321708 | 110201645 |
| Chronic obstructive pulmonary disease | 47.29 | 13.97 | 5 | 65941 | 109153 | 110414200 |
| Weight fluctuation | 47.11 | 13.97 | 62 | 65884 | 22083 | 110501270 |
| Prescribed underdose | 46.51 | 13.97 | 113 | 65833 | 65061 | 110458292 |
| Hepatic enzyme increased | 45.81 | 13.97 | 338 | 65608 | 320554 | 110202799 |
| Ear infection | 45.02 | 13.97 | 109 | 65837 | 62623 | 110460730 |
| Hypoaesthesia | 44.87 | 13.97 | 331 | 65615 | 313892 | 110209461 |
| Blister | 44.33 | 13.97 | 259 | 65687 | 227117 | 110296236 |
| Musculoskeletal pain | 43.45 | 13.97 | 220 | 65726 | 182803 | 110340550 |
| Foot deformity | 43.44 | 13.97 | 92 | 65854 | 48388 | 110474965 |
| Grip strength | 43.20 | 13.97 | 39 | 65907 | 9102 | 110514251 |
| Medication error | 42.55 | 13.97 | 149 | 65797 | 105217 | 110418136 |
| Hypertension | 42.47 | 13.97 | 478 | 65468 | 509606 | 110013747 |
| Respiratory disorder | 41.90 | 13.97 | 115 | 65831 | 71267 | 110452086 |
| Suicide attempt | 41.70 | 13.97 | 6 | 65940 | 103388 | 110419965 |
| Hip arthroplasty | 41.15 | 13.97 | 98 | 65848 | 55715 | 110467638 |
| Inspiratory capacity decreased | 40.63 | 13.97 | 23 | 65923 | 2572 | 110520781 |
| Constipation | 40.00 | 13.97 | 97 | 65849 | 357689 | 110165664 |
| Bone erosion | 39.26 | 13.97 | 86 | 65860 | 46285 | 110477068 |
| Insomnia | 39.17 | 13.97 | 357 | 65589 | 360233 | 110163120 |
| Subcutaneous drug absorption impaired | 38.83 | 13.97 | 34 | 65912 | 7625 | 110515728 |
| Product use issue | 38.23 | 13.97 | 317 | 65629 | 311378 | 110211975 |
| Breast cancer stage II | 37.08 | 13.97 | 62 | 65884 | 27313 | 110496040 |
| Dehydration | 36.90 | 13.97 | 69 | 65877 | 279442 | 110243911 |
| Blood pressure fluctuation | 36.66 | 13.97 | 113 | 65833 | 74711 | 110448642 |
| General symptom | 36.52 | 13.97 | 35 | 65911 | 8811 | 110514542 |
| Hyponatraemia | 36.13 | 13.97 | 46 | 65900 | 217607 | 110305746 |
| Gastrointestinal disorder | 35.75 | 13.97 | 257 | 65689 | 241695 | 110281658 |
| Swollen joint count | 35.20 | 13.97 | 34 | 65912 | 8640 | 110514713 |
| Lower respiratory tract infection | 34.64 | 13.97 | 256 | 65690 | 242850 | 110280503 |
| Urinary tract infection | 34.50 | 13.97 | 91 | 65855 | 326191 | 110197162 |
| Disseminated intravascular coagulation | 34.31 | 13.97 | 76 | 65870 | 41210 | 110482143 |
| Disability | 33.88 | 13.97 | 63 | 65883 | 30160 | 110493193 |
| Blood cholesterol increased | 33.78 | 13.97 | 207 | 65739 | 184578 | 110338775 |
| Intentional product misuse | 33.14 | 13.97 | 19 | 65927 | 132885 | 110390468 |
| Wrong technique in product usage process | 33.14 | 13.97 | 6 | 65940 | 87342 | 110436011 |
| Mobility decreased | 32.69 | 13.97 | 248 | 65698 | 237174 | 110286179 |
| Malignant neoplasm progression | 32.09 | 13.97 | 34 | 65912 | 174533 | 110348820 |
| Pulmonary embolism | 31.93 | 13.97 | 49 | 65897 | 214425 | 110308928 |
| Atrial fibrillation | 31.82 | 13.97 | 55 | 65891 | 229587 | 110293766 |
| Neuropathy peripheral | 31.76 | 13.97 | 36 | 65910 | 179241 | 110344112 |
| Gait inability | 31.71 | 13.97 | 163 | 65783 | 136213 | 110387140 |
| Anti-cyclic citrullinated peptide antibody positive | 31.48 | 13.97 | 201 | 65745 | 181783 | 110341570 |
| Cerebrovascular accident | 31.47 | 13.97 | 37 | 65909 | 181247 | 110342106 |
| Live birth | 31.35 | 13.97 | 102 | 65844 | 69382 | 110453971 |
| Pyrexia | 31.30 | 13.97 | 728 | 65218 | 897537 | 109625816 |
| Osteoporosis | 30.77 | 13.97 | 118 | 65828 | 87034 | 110436319 |
| Sleep disorder due to a general medical condition | 30.63 | 13.97 | 84 | 65862 | 52028 | 110471325 |
| Overdose | 30.60 | 13.97 | 58 | 65888 | 233736 | 110289617 |
| Suicidal ideation | 30.58 | 13.97 | 9 | 65937 | 93928 | 110429425 |
| Syncope | 29.46 | 13.97 | 47 | 65899 | 202489 | 110320864 |
| Coma | 29.18 | 13.97 | 17 | 65929 | 117852 | 110405501 |
| Haemoglobin decreased | 28.93 | 13.97 | 66 | 65880 | 248661 | 110274692 |
| Adverse event | 28.83 | 13.97 | 135 | 65811 | 108674 | 110414679 |
| Myalgia | 28.38 | 13.97 | 56 | 65890 | 222325 | 110301028 |
| Neutropenia | 28.28 | 13.97 | 121 | 65825 | 374499 | 110148854 |
| Bradycardia | 27.80 | 13.97 | 31 | 65915 | 155486 | 110367867 |
| Rectal haemorrhage | 27.70 | 13.97 | 143 | 65803 | 119690 | 110403663 |
| Hepatic cirrhosis | 27.62 | 13.97 | 96 | 65850 | 67530 | 110455823 |
| Transient ischaemic attack | 27.53 | 13.97 | 3 | 65943 | 63979 | 110459374 |
| Knee arthroplasty | 27.22 | 13.97 | 93 | 65853 | 64855 | 110458498 |
| Transaminases increased | 27.21 | 13.97 | 3 | 65943 | 63387 | 110459966 |
| Cardiac failure congestive | 27.10 | 13.97 | 30 | 65916 | 150970 | 110372383 |
| Osteoarthritis | 25.83 | 13.97 | 192 | 65754 | 182431 | 110340922 |
| Dyspnoea exertional | 25.77 | 13.97 | 15 | 65931 | 104045 | 110419308 |
| Injection site erythema | 25.65 | 13.97 | 12 | 65934 | 94164 | 110429189 |
| Pruritus | 25.30 | 13.97 | 487 | 65459 | 581073 | 109942280 |
| Migraine | 25.15 | 13.97 | 182 | 65764 | 171470 | 110351883 |
| Seronegative arthritis | 25.15 | 13.97 | 35 | 65911 | 13142 | 110510211 |
| Coronary artery disease | 24.98 | 13.97 | 6 | 65940 | 71684 | 110451669 |
| Aggression | 24.92 | 13.97 | 3 | 65943 | 59207 | 110464146 |
| Pregnancy | 24.90 | 13.97 | 77 | 65869 | 50990 | 110472363 |
| Anaphylactic shock | 24.46 | 13.97 | 77 | 65869 | 51469 | 110471884 |
| Nausea | 24.24 | 13.97 | 557 | 65389 | 1235133 | 109288220 |
| Blood glucose increased | 24.13 | 13.97 | 26 | 65920 | 132470 | 110390883 |
| Dysarthria | 24.05 | 13.97 | 10 | 65936 | 84111 | 110439242 |
| Sedation | 23.95 | 13.97 | 6 | 65940 | 69677 | 110453676 |
| Lethargy | 23.88 | 13.97 | 13 | 65933 | 93563 | 110429790 |
| Cardiac arrest | 23.87 | 13.97 | 51 | 65895 | 196702 | 110326651 |
| Haemothorax | 23.83 | 13.97 | 25 | 65921 | 7006 | 110516347 |
| Contusion | 23.79 | 13.97 | 228 | 65718 | 233133 | 110290220 |
| Rash vesicular | 23.72 | 13.97 | 36 | 65910 | 14616 | 110508737 |
| Rash | 23.44 | 13.97 | 648 | 65298 | 820316 | 109703037 |
| Cough | 23.43 | 13.97 | 170 | 65776 | 461471 | 110061882 |
| Pancreatitis | 23.30 | 13.97 | 114 | 65832 | 93419 | 110429934 |
| Ear pain | 23.00 | 13.97 | 77 | 65869 | 53149 | 110470204 |
| Red blood cell sedimentation rate increased | 22.87 | 13.97 | 100 | 65846 | 78202 | 110445151 |
| Pustular psoriasis | 22.84 | 13.97 | 34 | 65912 | 13571 | 110509782 |
| Gastrointestinal haemorrhage | 22.60 | 13.97 | 40 | 65906 | 165478 | 110357875 |
| Cognitive disorder | 22.56 | 13.97 | 12 | 65934 | 87499 | 110435854 |
| Thrombosis | 22.50 | 13.97 | 19 | 65927 | 108643 | 110414710 |
| Seizure | 22.38 | 13.97 | 63 | 65883 | 221122 | 110302231 |
| Balance disorder | 22.22 | 13.97 | 22 | 65924 | 116538 | 110406815 |
| Orthostatic hypotension | 22.21 | 13.97 | 6 | 65940 | 66243 | 110457110 |
| Hallucination | 21.92 | 13.97 | 17 | 65929 | 101415 | 110421938 |
| Cerebellar tumour | 21.87 | 13.97 | 7 | 65939 | 186 | 110523167 |
| Rheumatoid arthritis | 21.86 | 13.97 | 98 | 65848 | 299515 | 110223838 |
| Electrocardiogram QT prolonged | 21.43 | 13.97 | 20 | 65926 | 108940 | 110414413 |
| Lactic acidosis | 20.77 | 13.97 | 15 | 65931 | 92796 | 110430557 |
| Ascites | 20.77 | 13.97 | 15 | 65931 | 92793 | 110430560 |
| Pain in jaw | 20.56 | 13.97 | 3 | 65943 | 51174 | 110472179 |
| Renal failure | 20.46 | 13.97 | 68 | 65878 | 226506 | 110296847 |
| Anti-cyclic citrullinated peptide antibody | 20.39 | 13.97 | 40 | 65906 | 19924 | 110503429 |
| Therapy non-responder | 20.35 | 13.97 | 162 | 65784 | 157145 | 110366208 |
| Flushing | 20.20 | 13.97 | 119 | 65827 | 104617 | 110418736 |
| Injection site swelling | 19.96 | 13.97 | 6 | 65940 | 61784 | 110461569 |
| White blood cell count increased | 19.96 | 13.97 | 112 | 65834 | 96730 | 110426623 |
| Diverticulitis | 19.62 | 13.97 | 4 | 65942 | 53518 | 110469835 |
| Cholestasis | 19.55 | 13.97 | 7 | 65939 | 64511 | 110458842 |
| International normalised ratio increased | 19.45 | 13.97 | 14 | 65932 | 86758 | 110436595 |
| Drug resistance | 19.10 | 13.97 | 5 | 65941 | 56369 | 110466984 |
| Anaphylactic reaction | 18.99 | 13.97 | 125 | 65821 | 114175 | 110409178 |
| Joint swelling | 18.95 | 13.97 | 370 | 65576 | 442475 | 110080878 |
| Chronic kidney disease | 18.89 | 13.97 | 11 | 65935 | 76280 | 110447073 |
| Cardiac disorder | 18.88 | 13.97 | 11 | 65935 | 76269 | 110447084 |
| Influenza like illness | 18.88 | 13.97 | 15 | 65931 | 88397 | 110434956 |
| Osteonecrosis of jaw | 18.87 | 13.97 | 3 | 65943 | 48014 | 110475339 |
| Mental status changes | 18.81 | 13.97 | 11 | 65935 | 76111 | 110447242 |
| Metabolic acidosis | 18.81 | 13.97 | 19 | 65927 | 99725 | 110423628 |
| Cardio-respiratory arrest | 18.68 | 13.97 | 25 | 65921 | 115811 | 110407542 |
| Cytomegalovirus viraemia | 18.64 | 13.97 | 36 | 65910 | 17728 | 110505625 |
| Therapeutic product effect decreased | 18.53 | 13.97 | 225 | 65721 | 244091 | 110279262 |
| Angioedema | 18.31 | 13.97 | 19 | 65927 | 98481 | 110424872 |
| Acute myocardial infarction | 18.16 | 13.97 | 14 | 65932 | 83763 | 110439590 |
| Myoglobinaemia | 17.99 | 13.97 | 6 | 65940 | 182 | 110523171 |
| Cardiac failure | 17.85 | 13.97 | 55 | 65891 | 187571 | 110335782 |
| Abdominal discomfort | 17.85 | 13.97 | 332 | 65614 | 393526 | 110129827 |
| Hypoglycaemia | 17.78 | 13.97 | 26 | 65920 | 116078 | 110407275 |
| Skin ulcer | 17.50 | 13.97 | 8 | 65938 | 63637 | 110459716 |
| Joint stiffness | 17.50 | 13.97 | 83 | 65863 | 67160 | 110456193 |
| Drug reaction with eosinophilia and systemic symptoms | 17.44 | 13.97 | 14 | 65932 | 82081 | 110441272 |
| Hepatotoxicity | 17.39 | 13.97 | 8 | 65938 | 63392 | 110459961 |
| Adverse drug reaction | 17.27 | 13.97 | 115 | 65831 | 105444 | 110417909 |
| Adrenal insufficiency | 17.15 | 13.97 | 60 | 65886 | 42330 | 110481023 |
| Throat irritation | 16.88 | 13.97 | 70 | 65876 | 53482 | 110469871 |
| Irritability | 16.66 | 13.97 | 4 | 65942 | 47805 | 110475548 |
| Injection site bruising | 16.52 | 13.97 | 5 | 65941 | 51258 | 110472095 |
| Muscle spasms | 16.48 | 13.97 | 245 | 65701 | 277912 | 110245441 |
| Feeling abnormal | 16.47 | 13.97 | 54 | 65892 | 180657 | 110342696 |
| Polyglandular disorder | 16.41 | 13.97 | 6 | 65940 | 240 | 110523113 |
| Angiopathy | 16.38 | 13.97 | 23 | 65923 | 8707 | 110514646 |
| Middle ear inflammation | 16.25 | 13.97 | 6 | 65940 | 247 | 110523106 |
| Oropharyngeal discomfort | 16.19 | 13.97 | 25 | 65921 | 10302 | 110513051 |
| Interstitial lung disease | 16.17 | 13.97 | 37 | 65909 | 139297 | 110384056 |
| Dysphagia | 16.10 | 13.97 | 43 | 65903 | 153557 | 110369796 |
| Hepatitis | 16.04 | 13.97 | 18 | 65928 | 90036 | 110433317 |
| Hypotension | 16.03 | 13.97 | 218 | 65728 | 523631 | 109999722 |
| Accidental exposure to product | 15.90 | 13.97 | 5 | 65941 | 50003 | 110473350 |
| Obstructive airways disorder | 15.81 | 13.97 | 4 | 65942 | 46145 | 110477208 |
| Liver function test abnormal | 15.62 | 13.97 | 11 | 65935 | 68939 | 110454414 |
| External ear cellulitis | 15.62 | 13.97 | 6 | 65940 | 276 | 110523077 |
| Angina pectoris | 15.39 | 13.97 | 9 | 65937 | 62286 | 110461067 |
| Antithrombin III decreased | 15.13 | 13.97 | 7 | 65939 | 513 | 110522840 |
| Arthropathy | 15.04 | 13.97 | 248 | 65698 | 287274 | 110236079 |
| Visual impairment | 15.03 | 13.97 | 134 | 65812 | 134294 | 110389059 |
| Laboratory test abnormal | 15.00 | 13.97 | 59 | 65887 | 44020 | 110479333 |
| Enterococcus test positive | 14.94 | 13.97 | 13 | 65933 | 2891 | 110520462 |
| Gastrooesophageal reflux disease | 14.92 | 13.97 | 56 | 65890 | 179920 | 110343433 |
| Apocrine miliaria | 14.88 | 13.97 | 3 | 65943 | 10 | 110523343 |
| Exposure during pregnancy | 14.86 | 13.97 | 159 | 65787 | 167265 | 110356088 |
| Generalised tonic-clonic seizure | 14.84 | 13.97 | 7 | 65939 | 54673 | 110468680 |
| Unresponsive to stimuli | 14.69 | 13.97 | 10 | 65936 | 63780 | 110459573 |
| Onychomadesis | 14.64 | 13.97 | 60 | 65886 | 45603 | 110477750 |
| Arrhythmia | 14.61 | 13.97 | 12 | 65934 | 69563 | 110453790 |
| Hepatocellular injury | 14.51 | 13.97 | 6 | 65940 | 50636 | 110472717 |
| Anaplastic large cell lymphoma T- and null-cell types recurrent | 14.35 | 13.97 | 4 | 65942 | 65 | 110523288 |
| Hypercalcaemia | 14.24 | 13.97 | 5 | 65941 | 46652 | 110476701 |
| Rash maculo-papular | 14.15 | 13.97 | 14 | 65932 | 74208 | 110449145 |
| Pituitary tumour recurrent | 14.10 | 13.97 | 5 | 65941 | 183 | 110523170 |
| Polyp | 14.05 | 13.97 | 23 | 65923 | 9957 | 110513396 |
None
| Source | Code | Description |
|---|---|---|
| FDA MoA | N0000175450 | Corticosteroid Hormone Receptor Agonists |
| FDA EPC | N0000175576 | Corticosteroid |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| CHEBI has role | CHEBI:35610 | antineoplastic agent |
| CHEBI has role | CHEBI:65023 | anti-asthmatic agent |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Disorder of musculoskeletal system | indication | 928000 | DOID:17 |
| Cerebral edema | indication | 2032001 | |
| Berylliosis | indication | 8247009 | DOID:10322 |
| Psoriasis | indication | 9014002 | DOID:8893 |
| Ankylosing spondylitis | indication | 9631008 | DOID:7147 |
| Rheumatic heart disease | indication | 23685000 | |
| Atopic dermatitis | indication | 24079001 | DOID:3310 |
| Inflammatory bowel disease | indication | 24526004 | DOID:0050589 |
| Multiple sclerosis | indication | 24700007 | DOID:2377 |
| Severe adrenal insufficiency | indication | 24867002 | |
| Sarcoidosis | indication | 31541009 | DOID:11335 |
| Idiopathic thrombocytopenic purpura | indication | 32273002 | DOID:8924 |
| Psoriasis with arthropathy | indication | 33339001 | |
| Crohn's disease | indication | 34000006 | |
| Tendinitis | indication | 34840004 | DOID:971 |
| Erythema multiforme | indication | 36715001 | |
| Contact dermatitis | indication | 40275004 | DOID:2773 |
| Angioedema | indication | 41291007 | DOID:1558 |
| Humoral hypercalcemia of malignancy | indication | 47709007 | |
| Articular gout | indication | 48440001 | DOID:13189 |
| Edema of larynx | indication | 51599000 | |
| Nephrotic syndrome | indication | 52254009 | DOID:1184 |
| Systemic lupus erythematosus | indication | 55464009 | DOID:9074 |
| Allergic rhinitis | indication | 61582004 | |
| Löffler's syndrome | indication | 64936001 | DOID:9503 |
| Pemphigus | indication | 65172003 | DOID:9182 |
| Tenosynovitis | indication | 67801009 | DOID:970 |
| Rheumatoid arthritis | indication | 69896004 | DOID:7148 |
| Transfusion reaction due to serum protein reaction | indication | 72284000 | |
| Acquired thrombocytopenia | indication | 74576004 | DOID:11126 |
| Thyroiditis | indication | 82119001 | DOID:7166 |
| Bursitis | indication | 84017003 | DOID:2965 |
| Autoimmune disease | indication | 85828009 | |
| Infection by larvae of Trichinella spiralis | indication | 88264003 | |
| Congenital hypoplastic anemia | indication | 88854002 | DOID:1339 |
| Acute lymphoid leukemia | indication | 91857003 | DOID:9952 |
| Dermatitis herpetiformis | indication | 111196000 | DOID:8505 |
| Hodgkin's disease | indication | 118599009 | |
| Non-Hodgkin's lymphoma | indication | 118601006 | |
| Mycosis fungoides | indication | 118618005 | |
| Aspiration pneumonitis | indication | 155597006 | |
| Asthma | indication | 195967001 | DOID:2841 |
| Transplanted organ rejection | indication | 213148006 | |
| Adrenogenital disorder | indication | 267395000 | DOID:0050811 |
| Eruption of skin | indication | 271807003 | DOID:0050486 |
| Disorder of eye | indication | 371405004 | DOID:5614 |
| Primary adrenocortical insufficiency | indication | 373662000 | |
| Adrenal cortical hypofunction | indication | 386584007 | DOID:10493 |
| Erythroderma | indication | 399992009 | |
| Autoimmune hemolytic anemia | indication | 413603009 | DOID:718 |
| Synovitis | indication | 416209007 | DOID:2703 |
| Post traumatic osteoarthritis | indication | 699262001 | |
| Erythroblastic Anemia | indication | ||
| Diagnostic Test for Cushing's Syndrome | indication | ||
| Transfusion Reaction Urticaria | indication | ||
| Systemic Dermatomyositis | indication | ||
| Synovitis due to Osteoarthritis | indication | ||
| Respiratory distress syndrome in the newborn | off-label use | 46775006 | |
| Neonatal Bronchopulmonary Dysplasia | off-label use | ||
| Mycosis | contraindication | 3218000 | DOID:1564 |
| Ocular hypertension | contraindication | 4210003 | DOID:9282 |
| Inactive tuberculosis | contraindication | 11999007 | |
| Peptic ulcer | contraindication | 13200003 | DOID:750 |
| Measles | contraindication | 14189004 | DOID:8622 |
| Esophagitis | contraindication | 16761005 | DOID:11963 |
| Mood swings | contraindication | 18963009 | |
| Cirrhosis of liver | contraindication | 19943007 | DOID:5082 |
| Glaucoma | contraindication | 23986001 | DOID:1686 |
| Abscess of intestine | contraindication | 24557004 | |
| Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
| Infectious disease | contraindication | 40733004 | |
| Hypothyroidism | contraindication | 40930008 | DOID:1459 |
| Hypokalemia | contraindication | 43339004 | |
| Chronic heart failure | contraindication | 48447003 | |
| Duodenal ulcer disease | contraindication | 51868009 | DOID:1724 |
| Osteoporosis | contraindication | 64859006 | DOID:11476 |
| Psychotic disorder | contraindication | 69322001 | |
| Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
| Hypopituitarism | contraindication | 74728003 | DOID:9406 |
| Hyperglycemia | contraindication | 80394007 | DOID:4195 |
| Kidney disease | contraindication | 90708001 | DOID:557 |
| Bilateral cataracts | contraindication | 95722004 | |
| Eye infection | contraindication | 128351009 | |
| Disorder of muscle | contraindication | 129565002 | DOID:423 |
| Anastomosis of intestine | contraindication | 235407009 | |
| Diverticulitis of gastrointestinal tract | contraindication | 271366000 | |
| Varicella-zoster virus infection | contraindication | 309465005 | |
| Viral eye infection | contraindication | 312132001 | |
| Gastric ulcer | contraindication | 397825006 | DOID:10808 |
| Exposure to varicella | contraindication | 444453009 |
None
None
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 4.23 | acidic |
| pKa2 | 12.94 | acidic |
None
None
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Glucocorticoid receptor | Nuclear hormone receptor | AGONIST | CHEMBL | CHEMBL | |||||
| Glucocorticoid receptor | Transcription factor | Kd | 6.72 | CHEMBL |
| ID | Source |
|---|---|
| D00978 | KEGG_DRUG |
| 4017945 | VUID |
| N0000146295 | NUI |
| 4017941 | VANDF |
| 4017945 | VANDF |
| CHEBI:31677 | CHEBI |
| CHEMBL3989663 | ChEMBL_ID |
| CHEMBL1200495 | ChEMBL_ID |
| DB14545 | DRUGBANK_ID |
| C007133 | MESH_SUPPLEMENTAL_RECORD_UI |
| 16623 | PUBCHEM_CID |
| DB00741 | DRUGBANK_ID |
| 21651 | RXNORM |
| 20708 | MMSL |
| 2500 | MMSL |
| 41706 | MMSL |
| 4837 | MMSL |
| 4843 | MMSL |
| 73114 | MMSL |
| d00254 | MMSL |
| 002147 | NDDF |
| 002152 | NDDF |
| 005251 | NDDF |
| 109066000 | SNOMEDCT_US |
| 16602005 | SNOMEDCT_US |
| 396458002 | SNOMEDCT_US |
| 56423005 | SNOMEDCT_US |
| C0056387 | UMLSCUI |
| C0020268 | UMLSCUI |
| 83784-20-7 | SECONDARY_CAS_RN |
| 5754 | PUBCHEM_CID |
| 38 | INN_ID |
| D006854 | MESH_DESCRIPTOR_UI |
| 50LQB69S1Z | UNII |
| CHEBI:17650 | CHEBI |
| 50LQB69S1Z | INXIGHT DRUGS |
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Solu-Cortef | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0009-0005 | INJECTION, POWDER, FOR SOLUTION | 1000 mg | INTRAMUSCULAR | NDA | 22 sections |
| Solu-Cortef | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0009-0011 | INJECTION, POWDER, FOR SOLUTION | 100 mg | INTRAMUSCULAR | NDA | 22 sections |
| Solu-Cortef | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0009-0013 | INJECTION, POWDER, FOR SOLUTION | 250 mg | INTRAMUSCULAR | NDA | 22 sections |
| Solu-Cortef | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0009-0016 | INJECTION, POWDER, FOR SOLUTION | 500 mg | INTRAMUSCULAR | NDA | 22 sections |
| Solu-Cortef | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0009-0825 | INJECTION, POWDER, FOR SOLUTION | 100 mg | INTRAMUSCULAR | NDA | 22 sections |
| SOLU-CORTEF | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1261 | INJECTION, POWDER, FOR SOLUTION | 100 mg | INTRAMUSCULAR | NDA | 13 sections |
| SOLU-CORTEF | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1262 | INJECTION, POWDER, FOR SOLUTION | 250 mg | INTRAMUSCULAR | NDA | 13 sections |
| Solu-Cortef | HUMAN PRESCRIPTION DRUG LABEL | 1 | 55154-3942 | INJECTION, POWDER, FOR SOLUTION | 100 mg | INTRAMUSCULAR | NDA | 22 sections |
| Hydrocortisone sodium succinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60505-6411 | INJECTION, POWDER, FOR SOLUTION | 100 mg | INTRAMUSCULAR | ANDA | 21 sections |
| Hydrocortisone sodium succinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 69097-004 | INJECTION | 100 mg | INTRAMUSCULAR | ANDA | 11 sections |
| Hydrocortisone sodium succinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 70710-1907 | INJECTION | 100 mg | INTRAMUSCULAR | ANDA | 12 sections |
| Hydrocortisone sodium succinate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 70771-1966 | INJECTION | 100 mg | INTRAMUSCULAR | ANDA | 1 sections |
| Solu-Cortef | HUMAN PRESCRIPTION DRUG LABEL | 1 | 84549-011 | INJECTION, POWDER, FOR SOLUTION | 100 mg | INTRAMUSCULAR | NDA | 22 sections |