iodine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
radiopharmaceuticals, iodine-contained	4446	7553-56-2

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: iodine	A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically. Molecular weight: 253.81 Formula: I2 CLOGP: LIPINSKI: None HAC: 0 HDO: 0 TPSA: ALOGS: ROTB: 0

Molecule

Description

Molfile Inchi Smiles

Synonyms:

iodine

A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.

Molecular weight: 253.81
Formula: I2
CLOGP:
LIPINSKI: None
HAC: 0
HDO: 0
TPSA:
ALOGS:
ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Drug hypersensitivity	1349.71	14.95	660	6405	310027	63171930
Iodine allergy	82.92	14.95	19	7046	785	63481172
Lipoedema	41.47	14.95	9	7056	289	63481668
Fistula discharge	29.86	14.95	9	7056	1084	63480873
Spinal cord disorder	28.46	14.95	9	7056	1272	63480685
Oesophagitis	26.48	14.95	18	7047	14990	63466967
Vascular injury	26.24	14.95	8	7057	1002	63480955
Bladder spasm	25.51	14.95	9	7056	1779	63480178
Lymphoedema	25.47	14.95	16	7049	11676	63470281
Myelopathy	24.92	14.95	10	7055	2816	63479141

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FDA Adverse Event Reporting System (Male)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Drug hypersensitivity	261.47	21.23	122	2327	80407	34874075
Foetal exposure during pregnancy	47.85	21.23	31	2418	38070	34916412
Epispadias	37.87	21.23	7	2442	158	34954324
Dysmorphism	36.18	21.23	12	2437	3144	34951338
Iodine allergy	23.58	21.23	4	2445	54	34954428
Gastric bypass	22.44	21.23	5	2444	292	34954190
Drug tolerance	21.65	21.23	8	2441	2874	34951608
Dehydration	21.37	21.23	35	2414	129934	34824548

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FDA Adverse Event Reporting System (Geriatric)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Drug hypersensitivity	1427.39	15.07	621	6039	298295	79439433
Iodine allergy	59.52	15.07	13	6647	578	79737150
Lipoedema	28.70	15.07	6	6654	216	79737512
Premature delivery	28.44	15.07	20	6640	23447	79714281
Vascular injury	27.68	15.07	8	6652	1113	79736615
Relapsing multiple sclerosis	25.23	15.07	5	6655	137	79737591
Vulval cancer	23.37	15.07	6	6654	536	79737192
Infected lymphocele	22.54	15.07	5	6655	239	79737489
Preternatural anus	20.50	15.07	4	6656	101	79737627
Maternal exposure during pregnancy	20.42	15.07	39	6621	136499	79601229

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FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

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Source	Code	Description
ATC	D08AG01	DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Iodine products
ATC	D08AG03	DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Iodine products
CHEBI has role	CHEBI:33284	nutrients
CHEBI has role	CHEBI:27027	trace elements
CHEBI has role	CHEBI:77746	Homo sapiens metabolite
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000891	Anti-Infective Agents, Local
MeSH PA	D018977	Micronutrients
MeSH PA	D014131	Trace Elements

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Drug Use | Suggest Off label Use Form| |View source of the data|

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Disease	Relation	SNOMED_ID	DOID
Provision of therapeutic radionuclide	indication	74385000
CD20 Positive Non-Hodgkin's Lymphoma	indication
Neonatal thyrotoxicosis	off-label use	13795004	DOID:12573
Thyrotoxic crisis	off-label use	29028009	DOID:12837
Hyperthyroidism	off-label use	34486009	DOID:7998
Lymphocutaneous sporotrichosis	off-label use	87603003
Iodine deficiency	off-label use	238121000
Thyroid Surgery	off-label use
Thyroid Gland Radiation Protection	off-label use
Bacterial septicemia	contraindication	10001005	DOID:0040085

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🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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ID	Source
000852	NDDF
003150	NDDF
007599	NDDF
4017659	VUID
4017659	VANDF
44588005	SNOMEDCT_US
4900	MMSL
5933	RXNORM
767115003	SNOMEDCT_US
807	PUBCHEM_CID

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Pharmaceutical products:

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Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
De La Cruz Tincture of Iodine	HUMAN OTC DRUG LABEL	3	24286-1528	LIQUID	20 mg	TOPICAL	OTC monograph not final	13 sections
De La Cruz Tincture of Iodine	HUMAN OTC DRUG LABEL	3	24286-1528	LIQUID	20 mg	TOPICAL	OTC monograph not final	13 sections
GNP Idoinde Tincture 2% Mild	HUMAN OTC DRUG LABEL	3	24385-213	LIQUID	20 mg	TOPICAL	OTC monograph not final	14 sections
GNP Idoinde Tincture 2% Mild	HUMAN OTC DRUG LABEL	3	24385-213	LIQUID	20 mg	TOPICAL	OTC monograph not final	14 sections
Humco Strong Iodine	HUMAN PRESCRIPTION DRUG LABEL	2	0395-2775	LIQUID	50 mg	ORAL	unapproved drug other	12 sections
Humco Strong Iodine	HUMAN PRESCRIPTION DRUG LABEL	2	0395-2775	LIQUID	50 mg	ORAL	unapproved drug other	12 sections
Iodine	HUMAN OTC DRUG LABEL	3	0363-0088	LIQUID	20 mg	TOPICAL	OTC monograph not final	12 sections
Iodine	HUMAN OTC DRUG LABEL	3	0363-0088	LIQUID	20 mg	TOPICAL	OTC monograph not final	12 sections
Iodine	HUMAN OTC DRUG LABEL	3	0869-0088	LIQUID	20 mg	TOPICAL	OTC monograph not final	12 sections
Iodine	HUMAN OTC DRUG LABEL	3	0869-0088	LIQUID	20 mg	TOPICAL	OTC monograph not final	12 sections

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