dibutylphthalate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4414 | 84-74-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | P03BX03 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS INSECTICIDES AND REPELLENTS Other insecticides and repellents |
| MeSH PA | D010968 | Plasticizers |
| CHEBI has role | CHEBI:25212 | metabolites |
| CHEBI has role | CHEBI:50905 | teratogeno |
| CHEBI has role | CHEBI:67239 | glucosidoinvertase inhibitor |
| CHEBI has role | CHEBI:78298 | environmental contaminants |
| CHEBI has role | CHEBI:79056 | plasticizer |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily A member 1 | Ion channel | ACTIVATOR | EC50 | 4.60 | IUPHAR |
External reference:
| ID | Source |
|---|---|
| N0000166643 | NUI |
| C0012052 | UMLSCUI |
| CHEBI:34687 | CHEBI |
| DB7 | PDB_CHEM_ID |
| CHEMBL272485 | ChEMBL_ID |
| DB13716 | DRUGBANK_ID |
| 6295 | IUPHAR_LIGAND_ID |
| 2286E5R2KE | UNII |
| 3026 | PUBCHEM_CID |
| 1362873 | RXNORM |
| NOCODE | MMSL |
| 006320 | NDDF |
| 411442007 | SNOMEDCT_US |
| 4353000 | SNOMEDCT_US |
| D003993 | MESH_DESCRIPTOR_UI |
Pharmaceutical products:
None