clofenotane 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4396	50-29-3

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

dicophane
clofenotane
chlorophenothane
chlorphenothan
clofenotan

synthetic insecticide used to combat malaria, typhus, and the other insect-borne human diseases

Molecular weight: 354.48
Formula: C14H9Cl5
CLOGP: 6.76
LIPINSKI: 1
HAC: 0
HDO: 0
TPSA:
ALOGS: -8
ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	P03AB01	ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS ECTOPARASITICIDES, INCL. SCABICIDES Chlorine containing products
ATC	P03AB51	ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS ECTOPARASITICIDES, INCL. SCABICIDES Chlorine containing products
CHEBI has role	CHEBI:39412	bridged diphenyl acaricides
CHEBI has role	CHEBI:50903	carcinogen
CHEBI has role	CHEBI:77853	persistent organic pollutants
CHEBI has role	CHEBI:138015	endocrine disruptors

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Androgen receptor	Transcription factor		ANDR_RAT		IC50	4.74		CHEMBL

External reference:

ID	Source
D07367	KEGG_DRUG
C0011041	UMLSCUI
CHEBI:16130	CHEBI
CHEMBL416898	ChEMBL_ID
DB13424	DRUGBANK_ID
2202	INN_ID
CIW5S16655	UNII
3036	PUBCHEM_CID
002996	NDDF
6WT	PDB_CHEM_ID

Pharmaceutical products:

None