demecolcine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4375 | 477-30-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | L01CC01 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS ANTINEOPLASTIC AGENTS PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS Colchicine derivatives |
| CHEBI has role | CHEBI:35610 | antineoplastic agents |
| CHEBI has role | CHEBI:61951 | microtubule destabilizing role |
| MeSH PA | D050256 | Antimitotic Agents |
| MeSH PA | D000970 | Antineoplastic Agents |
| MeSH PA | D000972 | Antineoplastic Agents, Phytogenic |
| MeSH PA | D050257 | Tubulin Modulators |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 5.26 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| C0011259 | UMLSCUI |
| CHEBI:4393 | CHEBI |
| LON | PDB_CHEM_ID |
| CHEMBL433632 | ChEMBL_ID |
| CHEMBL312862 | ChEMBL_ID |
| DB13318 | DRUGBANK_ID |
| 509 | INN_ID |
| Z01IVE25KI | UNII |
| 220401 | PUBCHEM_CID |
| D003703 | MESH_DESCRIPTOR_UI |
Pharmaceutical products:
None