calcium gluconate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4348 299-28-5

Description:

MoleculeDescription

Synonyms:

  • calcium gluconate
  • calciofon
  • Calcium D-gluconate
  • calcium gluconate monohydrate
The calcium salt of gluconic acid. The compound has a variety of uses, including its use as a calcium replenisher in hypocalcemic states.
  • Molecular weight: 430.37
  • Formula: C12H22CaO14
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 141.28
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
3 g O

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Liver injury 739.01 15.37 459 38094 60061 63390408
Psoriatic arthropathy 625.87 15.37 486 38067 91034 63359435
Glossodynia 342.17 15.37 479 38074 178397 63272072
Pemphigus 326.42 15.37 475 38078 183251 63267218
Rheumatoid arthritis 284.32 15.37 533 38020 253286 63197183
Systemic lupus erythematosus 281.87 15.37 476 38077 208442 63242027
Arthropathy 272.88 15.37 501 38052 234291 63216178
Product use issue 210.24 15.37 433 38120 220087 63230382
Contraindicated product administered 201.19 15.37 422 38131 217226 63233243
Alopecia 197.43 15.37 548 38005 336988 63113481
Abdominal discomfort 172.03 15.37 505 38048 320380 63130089
Prescribed overdose 155.98 15.37 144 38409 34009 63416460
Hand deformity 155.22 15.37 316 38237 159141 63291328
Wound 143.13 15.37 310 38243 162953 63287516
Maternal exposure during pregnancy 133.07 15.37 362 38191 219700 63230769
Rheumatic fever 131.29 15.37 146 38407 42965 63407504
Fibromyalgia 129.70 15.37 199 38354 80221 63370248
Swollen joint count increased 120.07 15.37 128 38425 35926 63414543
Discomfort 111.97 15.37 286 38267 167088 63283381
Hip arthroplasty 97.43 15.37 132 38421 47514 63402955
Knee arthroplasty 90.00 15.37 136 38417 54070 63396399
Rheumatoid factor positive 88.90 15.37 173 38380 84233 63366236
Intentional product use issue 87.01 15.37 220 38333 127672 63322797
Pericarditis 86.05 15.37 223 38330 131356 63319113
Product dose omission issue 85.23 15.37 19 38534 234294 63216175
Blood cholesterol increased 81.67 15.37 178 38375 93854 63356615
Fall 81.65 15.37 71 38482 392263 63058206
Anti-cyclic citrullinated peptide antibody positive 81.23 15.37 202 38351 116010 63334459
Dislocation of vertebra 79.54 15.37 55 38498 8580 63441889
Type 2 diabetes mellitus 77.35 15.37 139 38414 63729 63386740
Duodenal ulcer perforation 76.78 15.37 166 38387 87043 63363426
Injury 75.75 15.37 149 38404 73098 63377371
Lupus vulgaris 74.35 15.37 46 38507 5948 63444521
Adjustment disorder with depressed mood 71.31 15.37 55 38498 10149 63440320
Live birth 69.89 15.37 82 38471 25548 63424921
Prescribed underdose 68.03 15.37 87 38466 29602 63420867
Oedema 64.36 15.37 166 38387 97456 63353013
Helicobacter infection 63.48 15.37 160 38393 92625 63357844
Synovitis 62.75 15.37 252 38301 186666 63263803
Anti-cyclic citrullinated peptide antibody 57.49 15.37 41 38512 6717 63443752
Mobility decreased 56.57 15.37 182 38371 120977 63329492
Swelling 55.21 15.37 320 38233 275058 63175411
Death 55.12 15.37 89 38464 374292 63076177
Product complaint 54.60 15.37 52 38501 12757 63437712
Treatment failure 51.33 15.37 248 38305 198795 63251674
Skin reaction 48.15 15.37 52 38501 14797 63435672
Dyspnoea 46.06 15.37 226 38327 661087 62789382
Drug interaction 45.76 15.37 43 38510 229088 63221381
Vascular access complication 44.62 15.37 23 38530 2095 63448374
Musculoskeletal deformity 43.92 15.37 22 38531 1887 63448582
Drug intolerance 43.80 15.37 329 38224 308332 63142137
Red cell distribution width decreased 42.28 15.37 22 38531 2043 63448426
Breast cancer stage III 42.07 15.37 41 38512 10345 63440124
Blood immunoglobulin A decreased 41.99 15.37 19 38534 1298 63449171
Blood immunoglobulin M increased 41.30 15.37 18 38535 1125 63449344
Toxicity to various agents 41.04 15.37 54 38499 247196 63203273
Deep vein thrombosis postoperative 40.76 15.37 42 38511 11327 63439142
Sciatica 40.64 15.37 74 38479 34250 63416219
Amnesia 40.26 15.37 98 38455 55487 63394982
Grip strength decreased 38.52 15.37 57 38496 22230 63428239
Facet joint syndrome 38.47 15.37 42 38511 12096 63438373
Peripheral venous disease 38.07 15.37 47 38506 15430 63435039
Blister 38.06 15.37 168 38385 129646 63320823
Infusion site reaction 35.77 15.37 24 38529 3563 63446906
Wheezing 35.39 15.37 133 38420 95462 63355007
Hepatic enzyme increased 35.36 15.37 227 38326 202101 63248368
Posthaemorrhagic hydrocephalus 35.16 15.37 7 38546 21 63450448
Lip dry 34.91 15.37 45 38508 15425 63435044
Wound infection 34.50 15.37 53 38500 21357 63429112
Mean platelet volume decreased 34.42 15.37 21 38532 2648 63447821
Injection site pain 34.29 15.37 18 38535 129782 63320687
Infusion related reaction 33.29 15.37 259 38294 245262 63205207
Autoimmune disorder 32.71 15.37 46 38507 17131 63433338
Influenza 31.93 15.37 13 38540 108709 63341760
Cough 31.67 15.37 83 38470 292660 63157809
Physical disability 31.35 15.37 20 38533 2728 63447741
Blood immunoglobulin G increased 31.05 15.37 19 38534 2408 63448061
Walking aid user 30.40 15.37 35 38518 10682 63439787
Pain 29.50 15.37 621 37932 740007 62710462
Back pain 29.25 15.37 74 38479 264071 63186398
Colitis microscopic 29.05 15.37 32 38521 9307 63441162
Mean cell volume decreased 29.02 15.37 22 38531 3956 63446513
Osteoarthritis 28.40 15.37 124 38429 95219 63355250
Mean cell haemoglobin decreased 27.93 15.37 24 38529 5155 63445314
Musculoskeletal stiffness 27.40 15.37 199 38354 184419 63266050
Adverse drug reaction 27.12 15.37 108 38445 79606 63370863
Maternal exposure before pregnancy 27.09 15.37 28 38525 7575 63442894
COVID-19 26.61 15.37 18 38535 113085 63337384
Urinary tract infection 26.42 15.37 78 38475 264606 63185863
Hypocalcaemia 26.34 15.37 59 38494 31654 63418815
Suspected transmission of an infectious agent via product 26.23 15.37 9 38544 293 63450176
Hypertension 25.74 15.37 271 38282 279032 63171437
Disease progression 25.73 15.37 22 38531 122736 63327733
Exposure during pregnancy 25.63 15.37 172 38381 155375 63295094
X-ray abnormal 25.59 15.37 28 38525 8082 63442387
Eye injury 25.39 15.37 18 38535 2921 63447548
Red blood cell sedimentation rate 25.17 15.37 22 38531 4832 63445637
Wrong technique in product usage process 24.88 15.37 4 38549 62336 63388133
Hiccups 24.86 15.37 16 38537 2215 63448254
Somnolence 24.84 15.37 44 38509 178641 63271828
Seronegative arthritis 24.78 15.37 20 38533 3939 63446530
Rheumatic disorder 24.67 15.37 18 38535 3054 63447415
Joint destruction 24.06 15.37 24 38529 6228 63444241
Balance disorder 23.36 15.37 11 38542 84411 63366058
Macular degeneration 23.29 15.37 48 38505 24328 63426141
Recalled product 23.28 15.37 13 38540 1390 63449079
Nail infection 23.07 15.37 16 38537 2507 63447962
Product compounding quality issue 22.47 15.37 5 38548 29 63450440
Disability 22.28 15.37 40 38513 18307 63432162
General physical health deterioration 22.25 15.37 203 38350 201199 63249270
Hospitalisation 22.17 15.37 12 38541 85069 63365400
Thrombosis 22.06 15.37 6 38547 64749 63385720
Tremor 21.80 15.37 29 38524 132210 63318259
Therapeutic product effect decreased 21.48 15.37 195 38358 192992 63257477
Cystic fibrosis 21.37 15.37 17 38536 3279 63447190
Hypoaesthesia 21.35 15.37 175 38378 168218 63282251
Productive cough 21.26 15.37 6 38547 63202 63387267
Adverse event 20.98 15.37 89 38464 67470 63382999
Inappropriate schedule of product administration 20.17 15.37 20 38533 103945 63346524
Syncope 20.12 15.37 25 38528 117360 63333109
Stress 19.77 15.37 8 38545 67159 63383310
Culture positive 19.53 15.37 8 38545 428 63450041
Hypercholesterolaemia 19.20 15.37 41 38512 21293 63429176
Neonatal infection 19.10 15.37 6 38547 147 63450322
Nasal congestion 19.04 15.37 8 38545 65652 63384817
Rhinorrhoea 18.99 15.37 8 38545 65569 63384900
Monocyte count increased 18.82 15.37 23 38530 7470 63442999
Hyperplastic cholecystopathy 18.73 15.37 6 38547 157 63450312
Oropharyngeal pain 18.53 15.37 18 38535 94469 63356000
Hypercalcaemia 18.48 15.37 48 38505 28274 63422195
Endometritis 18.46 15.37 10 38543 1008 63449461
Oxygen saturation decreased 18.41 15.37 16 38537 88569 63361900
Distributive shock 18.14 15.37 11 38542 1372 63449097
Malignant neoplasm progression 18.10 15.37 14 38539 82107 63368362
Influenza like illness 18.04 15.37 9 38544 66815 63383654
Hyperdynamic left ventricle 17.95 15.37 6 38547 180 63450289
Epistaxis 17.89 15.37 11 38542 72714 63377755
Blood calcium increased 17.74 15.37 25 38528 9325 63441144
Poor peripheral circulation 17.48 15.37 16 38537 3733 63446736
C-reactive protein 17.43 15.37 18 38535 4864 63445605
Myocardial infarction 17.40 15.37 21 38532 99872 63350597
Drug tolerance decreased 17.39 15.37 35 38518 17438 63433031
Electrocardiogram U wave present 17.07 15.37 5 38548 96 63450373
Injection site swelling 16.99 15.37 4 38549 47568 63402901
Feeling abnormal 16.86 15.37 41 38512 148351 63302118
Delirium 16.81 15.37 68 38485 50473 63399996
Therapeutic response decreased 16.80 15.37 78 38475 61447 63389022
Hepatic enzyme abnormal 16.68 15.37 20 38533 6372 63444097
Glaucoma 16.63 15.37 36 38517 18869 63431600
Cerebrovascular accident 16.50 15.37 25 38528 107999 63342470
Insomnia 16.43 15.37 71 38482 215181 63235288
Vision blurred 16.36 15.37 19 38534 91905 63358564
Hypersensitivity 16.35 15.37 259 38294 292426 63158043
Blood pressure fluctuation 16.33 15.37 4 38549 46313 63404156
Pruritus 16.17 15.37 141 38412 361312 63089157
Multiple drug therapy 15.92 15.37 15 38538 3631 63446838
Lower limb fracture 15.75 15.37 41 38512 24180 63426289
Neutropenia 15.75 15.37 54 38499 174951 63275518
Interstitial lung disease 15.74 15.37 9 38544 61899 63388570
Myalgia 15.48 15.37 42 38511 146487 63303982
Underdose 15.38 15.37 44 38509 27412 63423057

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Toxic epidermal necrolysis 150.96 15.83 85 9093 21561 34926192
Lymphocyte count decreased 62.57 15.83 50 9128 22572 34925181
Multiple organ dysfunction syndrome 52.19 15.83 81 9097 76485 34871268
Cytokine release syndrome 45.76 15.83 42 9136 22835 34924918
Hypocalcaemia 45.52 15.83 43 9135 24246 34923507
Blood uric acid increased 41.91 15.83 28 9150 9596 34938157
Blood phosphorus increased 39.86 15.83 25 9153 7696 34940057
Hypokalaemia 37.45 15.83 60 9118 58154 34889599
Sepsis 32.69 15.83 107 9071 166454 34781299
Hyperphosphataemia 32.46 15.83 18 9160 4419 34943334
Myasthenia gravis 32.18 15.83 21 9157 6919 34940834
Red blood cells urine positive 30.51 15.83 13 9165 1796 34945957
Appendicolith 30.36 15.83 22 9156 8579 34939174
Incision site pain 30.31 15.83 13 9165 1825 34945928
Immune effector cell-associated neurotoxicity syndrome 29.76 15.83 16 9162 3697 34944056
Cardiogenic shock 28.42 15.83 35 9143 26583 34921170
Blood urea increased 27.81 15.83 37 9141 30327 34917426
Ventricular fibrillation 27.49 15.83 32 9146 22922 34924831
Protein urine present 27.17 15.83 17 9161 5211 34942542
Benign abdominal neoplasm 26.86 15.83 6 9172 90 34947663
Procedural pain 25.91 15.83 16 9162 4790 34942963
Hypophosphataemia 25.53 15.83 22 9156 11004 34936749
Posthaemorrhagic hydrocephalus 25.24 15.83 6 9172 120 34947633
Hypotension 24.52 15.83 119 9059 221530 34726223
Herpes zoster reactivation 24.42 15.83 7 9171 296 34947457
Neutrophil count increased 24.12 15.83 26 9152 17120 34930633
Wrong patient 24.00 15.83 6 9172 149 34947604
Chest expansion decreased 24.00 15.83 6 9172 149 34947604
Appendicitis 23.60 15.83 24 9154 14783 34932970
Hyponatraemia 22.78 15.83 60 9118 82631 34865122
Blood creatinine increased 22.30 15.83 65 9113 94911 34852842
Abdominal distension 22.12 15.83 48 9130 58444 34889309
Blood cholesterol increased 21.91 15.83 27 9151 20516 34927237
Hyperkalaemia 21.88 15.83 53 9125 69336 34878417
Product preparation error 21.46 15.83 11 9167 2306 34945447
Scrotal pain 20.37 15.83 8 9170 898 34946855
Lactobacillus test positive 20.20 15.83 4 9174 32 34947721
Cardiac arrest 19.93 15.83 63 9115 96096 34851657
Analgesic therapy 19.62 15.83 8 9170 990 34946763
Hypoxia 19.46 15.83 44 9134 55051 34892702
Sleep disorder therapy 19.42 15.83 8 9170 1015 34946738
Hypercalcaemia 19.25 15.83 22 9156 15446 34932307
Axial spondyloarthritis 19.13 15.83 6 9172 346 34947407
Stress 19.11 15.83 31 9147 30316 34917437
Delayed graft function 19.01 15.83 10 9168 2211 34945542
Drug therapy 18.58 15.83 8 9170 1133 34946620
Blood albumin decreased 18.08 15.83 20 9158 13552 34934201
Pantoea agglomerans infection 18.03 15.83 4 9174 58 34947695
Respiratory failure 17.99 15.83 66 9112 108506 34839247
Hyperdynamic left ventricle 17.99 15.83 5 9173 189 34947564
Hypothalamo-pituitary disorder 17.51 15.83 7 9171 823 34946930
Product dose omission issue 17.28 15.83 5 9173 119706 34828047
Hepatitis 17.25 15.83 26 9152 23878 34923875
Fungal sepsis 17.24 15.83 7 9171 857 34946896
Aspartate aminotransferase increased 16.49 15.83 47 9131 67736 34880017

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Liver injury 207.21 13.51 186 36238 56428 79651536
Psoriatic arthropathy 186.25 13.51 203 36221 77796 79630168
Rheumatic fever 155.19 13.51 118 36306 28407 79679557
Swollen joint count increased 136.23 13.51 100 36324 22827 79685137
Pemphigus 131.73 13.51 193 36231 99389 79608575
Glossodynia 129.13 13.51 195 36229 103142 79604822
Blood cholesterol increased 123.60 13.51 171 36253 83549 79624415
Hand deformity 121.28 13.51 190 36234 103729 79604235
Fibromyalgia 120.84 13.51 148 36276 64192 79643772
Prescribed overdose 114.60 13.51 112 36312 37771 79670193
Hip arthroplasty 108.70 13.51 106 36318 35650 79672314
Toxic epidermal necrolysis 101.13 13.51 113 36311 44468 79663496
Knee arthroplasty 100.47 13.51 111 36313 43137 79664827
Pericarditis 98.04 13.51 173 36251 104063 79603901
Systemic lupus erythematosus 96.28 13.51 187 36237 120962 79587002
Wound 95.61 13.51 182 36242 115997 79591967
Anti-cyclic citrullinated peptide antibody positive 95.58 13.51 151 36273 82992 79624972
Dislocation of vertebra 93.18 13.51 53 36371 7827 79700137
Completed suicide 88.84 13.51 6 36418 245761 79462203
Adjustment disorder with depressed mood 86.18 13.51 53 36371 9033 79698931
Duodenal ulcer perforation 82.75 13.51 125 36299 66086 79641878
Rheumatoid factor positive 82.04 13.51 118 36306 59721 79648243
Live birth 81.52 13.51 68 36356 18676 79689288
Discomfort 81.10 13.51 178 36246 125439 79582525
Arthropathy 80.26 13.51 219 36205 176892 79531072
Rheumatoid arthritis 80.18 13.51 243 36181 208227 79499737
Maternal exposure during pregnancy 75.48 13.51 182 36242 136356 79571608
Product complaint 74.31 13.51 56 36368 13293 79694671
Type 2 diabetes mellitus 73.03 13.51 109 36315 57013 79650951
Fall 69.73 13.51 72 36352 487557 79220407
Alopecia 68.66 13.51 247 36177 231108 79476856
Helicobacter infection 68.52 13.51 118 36306 69586 79638378
Contraindicated product administered 67.61 13.51 191 36233 157347 79550617
Synovitis 66.90 13.51 185 36239 150549 79557415
Mobility decreased 66.61 13.51 162 36262 122013 79585951
Injury 65.71 13.51 123 36301 77373 79630591
Prescribed underdose 58.83 13.51 70 36354 29444 79678520
Product dose omission issue 58.54 13.51 20 36404 247517 79460447
Lupus vulgaris 57.89 13.51 29 36395 3317 79704647
Treatment failure 56.63 13.51 189 36235 170297 79537667
Musculoskeletal deformity 54.23 13.51 22 36402 1534 79706430
Sciatica 53.78 13.51 71 36353 33151 79674813
Drug abuse 53.28 13.51 6 36418 162685 79545279
Death 53.27 13.51 112 36312 566402 79141562
Toxicity to various agents 52.94 13.51 69 36355 421471 79286493
Hypocalcaemia 52.35 13.51 87 36337 49837 79658127
Breast cancer stage III 52.00 13.51 40 36384 9786 79698178
Vascular access complication 50.20 13.51 23 36401 2159 79705805
Drug interaction 50.07 13.51 70 36354 415113 79292851
Facet joint syndrome 49.14 13.51 41 36383 11261 79696703
Red cell distribution width decreased 48.52 13.51 22 36402 2016 79705948
Blister 48.47 13.51 142 36282 119334 79588630
Grip strength decreased 47.14 13.51 54 36370 21815 79686149
Blood immunoglobulin A decreased 45.40 13.51 19 36405 1434 79706530
Anti-cyclic citrullinated peptide antibody 45.22 13.51 30 36394 5822 79702142
Deep vein thrombosis postoperative 44.68 13.51 38 36386 10714 79697250
Oedema 44.62 13.51 138 36286 119442 79588522
Peripheral venous disease 44.34 13.51 45 36379 15864 79692100
Hepatic enzyme increased 44.33 13.51 183 36241 182427 79525537
Blood immunoglobulin M increased 43.15 13.51 18 36406 1348 79706616
Intentional product use issue 43.06 13.51 160 36264 151952 79556012
Swelling 42.66 13.51 204 36220 216507 79491457
Hypoaesthesia 42.18 13.51 178 36246 179174 79528790
Mean platelet volume decreased 41.95 13.51 22 36402 2768 79705196
Lip dry 41.86 13.51 43 36381 15375 79692589
Wound infection 41.52 13.51 53 36371 23938 79684026
Drug intolerance 40.52 13.51 232 36192 263887 79444077
Autoimmune disorder 37.47 13.51 42 36382 16570 79691394
Infusion site reaction 37.33 13.51 22 36402 3471 79704493
Abdominal discomfort 35.72 13.51 216 36208 250511 79457453
Hypercalcaemia 35.09 13.51 63 36361 38367 79669597
Therapeutic product effect decreased 34.99 13.51 158 36266 163705 79544259
Product use issue 34.63 13.51 188 36236 209634 79498330
Walking aid user 34.47 13.51 32 36392 10116 79697848
Hyperdynamic left ventricle 34.18 13.51 11 36413 392 79707572
Physical disability 33.23 13.51 20 36404 3278 79704686
Blood immunoglobulin G increased 32.40 13.51 19 36405 2970 79704994
Osteoarthritis 31.86 13.51 100 36324 87209 79620755
X-ray abnormal 31.50 13.51 24 36400 5789 79702175
Joint destruction 31.09 13.51 24 36400 5901 79702063
Infusion related reaction 30.07 13.51 194 36230 230043 79477921
Multiple organ dysfunction syndrome 29.56 13.51 121 36303 120125 79587839
Rheumatic disorder 28.88 13.51 18 36406 3140 79704824
Suspected transmission of an infectious agent via product 28.86 13.51 13 36411 1173 79706791
Disability 28.34 13.51 37 36387 17083 79690881
Blood calcium increased 28.22 13.51 29 36395 10371 79697593
Incision site pain 28.10 13.51 17 36407 2813 79705151
Mean cell volume decreased 28.08 13.51 21 36403 4926 79703038
Red blood cell sedimentation rate 28.03 13.51 22 36402 5543 79702421
Nail infection 28.00 13.51 16 36408 2383 79705581
Mean cell haemoglobin decreased 27.93 13.51 23 36401 6201 79701763
Dyspnoea 27.85 13.51 254 36170 856771 78851193
COVID-19 27.74 13.51 19 36405 157655 79550309
Amnesia 27.55 13.51 77 36347 62980 79644984
Joint range of motion decreased 27.17 13.51 52 36372 33230 79674734
Seronegative arthritis 26.82 13.51 20 36404 4672 79703292
Adverse event 26.78 13.51 74 36350 60140 79647824
Poor peripheral circulation 26.35 13.51 18 36406 3665 79704299
Culture positive 26.31 13.51 12 36412 1114 79706850
Hypersensitivity 26.13 13.51 207 36217 262032 79445932
Wheezing 26.04 13.51 114 36310 116550 79591414
Adverse drug reaction 25.11 13.51 77 36347 66315 79641649
Recalled product 24.95 13.51 11 36413 943 79707021
Vaginal discharge 24.32 13.51 23 36401 7440 79700524
Colitis microscopic 23.90 13.51 27 36397 10741 79697223
Lower limb fracture 23.72 13.51 40 36384 23175 79684789
Influenza 23.63 13.51 15 36409 129591 79578373
Hyperphosphataemia 23.40 13.51 21 36403 6355 79701609
Endometritis 23.36 13.51 10 36414 798 79707166
Paraesthesia oral 23.26 13.51 37 36387 20434 79687530
Pantoea agglomerans infection 23.20 13.51 6 36418 96 79707868
Hypertension 23.14 13.51 242 36182 330750 79377214
Blood phosphorus increased 23.06 13.51 26 36398 10321 79697643
Blood uric acid increased 22.31 13.51 29 36395 13331 79694633
Product compounding quality issue 22.28 13.51 5 36419 42 79707922
Myocardial infarction 22.20 13.51 31 36393 184098 79523866
Night sweats 22.16 13.51 63 36361 52032 79655932
General physical health deterioration 22.04 13.51 207 36217 275031 79432933
Muscle injury 21.91 13.51 60 36364 48501 79659463
C-reactive protein 21.52 13.51 18 36406 4961 79703003
White blood cell count increased 21.51 13.51 79 36345 74554 79633410
Procedural pain 21.27 13.51 38 36386 23046 79684918
Hypophosphataemia 21.27 13.51 35 36389 19878 79688086
Small for dates baby 21.06 13.51 8 36416 468 79707496
Lymphocyte count decreased 20.91 13.51 58 36366 47231 79660733
Monocyte count increased 20.77 13.51 25 36399 10636 79697328
Musculoskeletal stiffness 20.75 13.51 144 36280 174864 79533100
Balance disorder 20.10 13.51 10 36414 98847 79609117
Neutropenia 20.02 13.51 66 36358 287644 79420320
Appendicolith 19.94 13.51 22 36402 8529 79699435
Inappropriate schedule of product administration 19.89 13.51 19 36405 133609 79574355
Injection site pain 19.87 13.51 18 36406 129820 79578144
Myasthenia gravis 19.63 13.51 24 36400 10375 79697589
Skin reaction 19.59 13.51 30 36394 16038 79691926
Red blood cells urine positive 19.52 13.51 17 36407 4946 79703018
Deformity 19.50 13.51 23 36401 9582 79698382
Chest expansion decreased 19.35 13.51 6 36418 189 79707775
Multiple fractures 19.32 13.51 21 36403 8005 79699959
Cardiac failure congestive 19.22 13.51 22 36402 142380 79565584
Distributive shock 18.91 13.51 13 36411 2674 79705290
Hypokalaemia 18.56 13.51 121 36303 143919 79564045
Hyperplastic cholecystopathy 18.56 13.51 6 36418 217 79707747
Cardiogenic shock 18.13 13.51 51 36373 41863 79666101
Hepatic enzyme abnormal 18.05 13.51 20 36404 7790 79700174
Lactobacillus test positive 17.88 13.51 4 36420 33 79707931
Cytokine release syndrome 17.78 13.51 46 36378 35952 79672012
Memory impairment 17.66 13.51 99 36325 111635 79596329
Disease progression 17.65 13.51 36 36388 184326 79523638
Hypercholesterolaemia 17.53 13.51 35 36389 23060 79684904
Wrong technique in product usage process 17.39 13.51 6 36418 73869 79634095
C-reactive protein abnormal 17.27 13.51 55 36369 48312 79659652
Irritable bowel syndrome 17.20 13.51 65 36359 62176 79645788
Benign abdominal neoplasm 17.09 13.51 6 36418 280 79707684
Electrocardiogram U wave present 17.04 13.51 5 36419 130 79707834
C-reactive protein increased 17.00 13.51 109 36315 128918 79579046
Protein urine present 16.96 13.51 22 36402 10090 79697874
Cataract operation 16.94 13.51 16 36408 5169 79702795
Drug tolerance decreased 16.91 13.51 25 36399 12953 79695011
Interstitial lung disease 16.77 13.51 16 36408 112584 79595380
Malignant neoplasm progression 16.29 13.51 23 36401 135967 79571997
Glaucoma 16.28 13.51 31 36393 19730 79688234
Folliculitis 16.28 13.51 59 36365 55321 79652643
Multiple drug therapy 16.10 13.51 14 36410 4064 79703900
Retinitis 15.79 13.51 16 36408 5627 79702337
Analgesic therapy 15.29 13.51 8 36416 1001 79706963
Joint swelling 15.25 13.51 200 36224 288446 79419518
Blood urea increased 15.22 13.51 53 36371 48737 79659227
Sleep disorder therapy 15.18 13.51 8 36416 1016 79706948
Neutrophil count increased 14.97 13.51 38 36386 29358 79678606
Bursitis 14.90 13.51 43 36381 35801 79672163
Syncope 14.78 13.51 38 36386 179411 79528553
Colour blindness 14.71 13.51 6 36418 424 79707540
Dry mouth 14.59 13.51 79 36345 87940 79620024
Cough 14.49 13.51 103 36321 366686 79341278
Hepatotoxicity 14.29 13.51 3 36421 51349 79656615
Hiccups 14.06 13.51 20 36404 10011 79697953
Drug therapy 13.99 13.51 8 36416 1193 79706771
CSF pressure increased 13.84 13.51 5 36419 254 79707710
Delayed graft function 13.77 13.51 12 36412 3495 79704469
Nasal congestion 13.76 13.51 9 36415 76543 79631421
Suicidal ideation 13.69 13.51 9 36415 76331 79631633
Stomatitis 13.60 13.51 114 36310 146643 79561321
Blepharospasm 13.55 13.51 15 36409 5836 79702128

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A12AA03 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
CALCIUM
Calcium
ATC D11AX03 DERMATOLOGICALS
OTHER DERMATOLOGICAL PREPARATIONS
OTHER DERMATOLOGICAL PREPARATIONS
Other dermatologicals
CHEBI has role CHEBI:50733 Dietary Supplement

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Osteoporosis indication 64859006 DOID:11476
Hypocalcemic tetany indication 190869004
Necrotizing enterocolitis in fetus OR newborn contraindication 2707005
Alcoholism contraindication 7200002
Poisoning by digitalis glycoside contraindication 12876009
Peptic ulcer contraindication 13200003 DOID:750
Constipation contraindication 14760008 DOID:2089
Hyperphosphatemia contraindication 20165001 DOID:0050459
Hypervitaminosis D contraindication 27712000 DOID:9971
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
Hypertensive disorder contraindication 38341003 DOID:10763
Gastrointestinal ulcer contraindication 40845000
Conduction disorder of the heart contraindication 44808001
End stage renal disease contraindication 46177005 DOID:784
Humoral hypercalcemia of malignancy contraindication 47709007
Vitamin K deficiency contraindication 52675005 DOID:11249
Nasal polyp contraindication 52756005
Heart disease contraindication 56265001 DOID:114
Acute nephropathy contraindication 58574008
Hepatic failure contraindication 59927004
Hypercalcemia contraindication 66931009 DOID:12678
Hyperparathyroidism contraindication 66999008 DOID:13543
Poisoning by acetaminophen contraindication 70273001
Agoraphobia contraindication 70691001 DOID:593
Ventricular fibrillation contraindication 71908006
Hypercalciuria contraindication 71938000
Factor II deficiency contraindication 73975000
Reye's syndrome contraindication 74351001 DOID:14525
Gastrointestinal hemorrhage contraindication 74474003
Thrombotic thrombocytopenic purpura contraindication 78129009 DOID:10772
Gout contraindication 90560007 DOID:13189
Kidney disease contraindication 90708001 DOID:557
Hemophilia contraindication 90935002
Kidney stone contraindication 95570007
Anemia due to enzyme deficiency contraindication 111577008
von Willebrand disorder contraindication 128105004 DOID:12531
Seizure disorder contraindication 128613002
Obsessive-compulsive disorder contraindication 191736004 DOID:10933
Insomnia contraindication 193462001
Impaired renal function disorder contraindication 197663003
Osteolysis contraindication 203522001
Disease of liver contraindication 235856003 DOID:409
Anemia contraindication 271737000 DOID:2355
Pregnancy, function contraindication 289908002
Thrombocytopenic disorder contraindication 302215000 DOID:1588
Arteriosclerosis obliterans contraindication 361133006 DOID:5160
Panic disorder contraindication 371631005 DOID:594
Breastfeeding (mother) contraindication 413712001
Myocardial ischemia contraindication 414795007 DOID:3393
Myocardial infarction in recovery phase contraindication 418044006
Acute erosive gastritis contraindication 444926003




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
1GM/10ML (100MG/ML) CALCIUM GLUCONATE NIVAGEN PHARMS INC A213071 Oct. 14, 2022 RX SOLUTION INTRAVENOUS May 5, 2023 COMPETITIVE GENERIC THERAPY

Bioactivity Summary:

None

External reference:

IDSource
4018087 VUID
N0000146426 NUI
D00935 KEGG_DRUG
66905-23-5 SECONDARY_CAS_RN
4018087 VANDF
C0006699 UMLSCUI
CHEBI:3309 CHEBI
CHEMBL2106119 ChEMBL_ID
D002125 MESH_DESCRIPTOR_UI
DB11126 DRUGBANK_ID
SQE6VB453K UNII
9290 PUBCHEM_CID
1298846 RXNORM
20 MMSL
4337 MMSL
71865 MMSL
d03800 MMSL
000777 NDDF
007049 NDDF
387292008 SNOMEDCT_US
53691001 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 0264-5600 INJECTION, SOLUTION 98 mg INTRAVENOUS ANDA 23 sections
Calgonate Calcium Gluconate Gel2.5% HUMAN OTC DRUG LABEL 1 0295-7520 GEL 2.50 g TOPICAL unapproved drug other 8 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 0404-9831 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 16 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 0404-9831 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 16 sections
Dairy Allergen Mix HUMAN OTC DRUG LABEL 38 43742-1277 LIQUID 6 [hp_C] ORAL unapproved drug other 9 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 44567-620 INJECTION, SOLUTION 20 mg INTRAVENOUS NDA 22 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 44567-621 INJECTION, SOLUTION 20 mg INTRAVENOUS NDA 22 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 44567-622 INJECTION, SOLUTION 10 mg INTRAVENOUS NDA 22 sections
Calcium Gluconate Human Prescription Drug Label 1 50090-3398 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 23 sections
CALCIUM GLUCONATE HUMAN PRESCRIPTION DRUG LABEL 1 51662-1312 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 17 sections
CALCIUM GLUCONATE HUMAN PRESCRIPTION DRUG LABEL 1 51662-1312 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 17 sections
CALCIUM GLUCONATE HUMAN PRESCRIPTION DRUG LABEL 1 51662-1347 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 17 sections
CALCIUM GLUCONATE HUMAN PRESCRIPTION DRUG LABEL 1 51662-1347 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 17 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 52584-360 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 15 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 52584-360 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 15 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 63323-360 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 26 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 63323-360 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 26 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 65219-162 INJECTION, SOLUTION 20 mg INTRAVENOUS NDA 23 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 65219-162 INJECTION, SOLUTION 20 mg INTRAVENOUS NDA 23 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 65219-164 INJECTION, SOLUTION 20 mg INTRAVENOUS NDA 23 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 65219-164 INJECTION, SOLUTION 20 mg INTRAVENOUS NDA 23 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 71872-7222 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 23 sections
Calcium Gluconate HUMAN PRESCRIPTION DRUG LABEL 1 71872-7222 INJECTION, SOLUTION 98 mg INTRAVENOUS NDA 23 sections
calcium gluconate Human Prescription Drug Label 1 75834-171 INJECTION, SOLUTION 98 mg INTRAVENOUS ANDA 23 sections