DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
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L1000
FAQ
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
arbutin 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
4267
497-76-7
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
arbutin
arbutine
arbutoside
arbutyne
hydroquinone glucose
Molecular weight: 272.25
Formula: C12H16O7
CLOGP: -1
LIPINSKI: 0
HAC: 7
HDO: 5
TPSA: 119.61
ALOGS: -0.84
ROTB: 3
Drug dosage:
None
ADMET properties:
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Property
Value
Reference
S (Water solubility)
50 mg/mL
Bocci G, Oprea TI, Benet LZ
BDDCS (Biopharmaceutical Drug Disposition Classification System)
1
Bocci G, Oprea TI, Benet LZ
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Approvals:
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Date
Agency
Company
Orphan
None
FDA
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FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
CHEBI has role
CHEBI:76924
plant metabolites
CHEBI has role
CHEBI:76971
Escherichia coli metabolites
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
9.87
acidic
pKa2
11.99
acidic
pKa3
12.61
acidic
pKa4
13.44
acidic
Showing 1 to 4 of 4 entries
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Tyrosinase
Enzyme
P14679
TYRO_HUMAN
IC50
4.52
CHEMBL
Polyphenol oxidase 2
Enzyme
PPO2_AGABI
IC50
4
CHEMBL
Tyrosinase
Enzyme
TYRO_MOUSE
IC50
4.52
CHEMBL
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External reference:
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entries
Search:
ID
Source
1367175
RXNORM
440936
PUBCHEM_CID
7OQ
PDB_CHEM_ID
C0003729
UMLSCUI
C5INA23HXF
UNII
CHEBI:18305
CHEBI
CHEMBL232202
ChEMBL_ID
D001104
MESH_DESCRIPTOR_UI
DB11217
DRUGBANK_ID
N0000168438
NUI
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
ABALONE CRYSTALDOUBLE EX AMPOULE
HUMAN OTC DRUG LABEL
2
60611-0006
LIQUID
2.20 g
TOPICAL
unapproved drug other
7 sections
Absolute Total BB SPF37 PA 3Plus
HUMAN OTC DRUG LABEL
4
49715-011
CREAM
0.80 g
TOPICAL
OTC monograph final
10 sections
CELLBN DAMAGE OVERNIGHT RECOVERY
HUMAN OTC DRUG LABEL
2
71450-0001
CREAM
2 g
TOPICAL
unapproved drug other
7 sections
Conju Princess BB
HUMAN OTC DRUG LABEL
3
59915-1001
CREAM
2 mL
TOPICAL
unapproved drug other
8 sections
Conju Princess BB
HUMAN OTC DRUG LABEL
3
59915-3001
CREAM
2 mL
TOPICAL
unapproved drug other
8 sections
D-ONE BY TAMDOAN BB MEDIUM
HUMAN OTC DRUG LABEL
8
70931-0003
CREAM
2 g
TOPICAL
unapproved drug other
7 sections
D-ONE BY TAMDOAN SUNSCREEN 50
HUMAN OTC DRUG LABEL
8
70931-0001
CREAM
2 g
TOPICAL
unapproved drug other
8 sections
Derma Blemish Balmblemish balm
HUMAN OTC DRUG LABEL
3
52554-4001
CREAM
0.02 mL
TOPICAL
unapproved drug other
6 sections
Dr G Whitening FORTIFIER by EGF
HUMAN OTC DRUG LABEL
2
43948-4001
CREAM
0.60 mL
TOPICAL
OTC monograph final
8 sections
Dr G Whitening REFORMER by EGF
HUMAN OTC DRUG LABEL
2
43948-4002
CREAM
1 mL
TOPICAL
OTC monograph final
8 sections
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arbutin