cineole Indications/Contra | FAERs | Orange Book | BioActivity |

Stem definitionDrug idCAS RN
4259 470-82-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • eucalyptol
  • eucaliptol
  • cineol
  • eucalyptole
  • eucalytol
  • eukalyptol
  • cineole
A monoterpene and cyclohexanol derivative that is the major component of EUCALYPTUS OIL. It is used in mouthwash, insect repellent, and as a cough suppressant, and also is widely used as a flavoring agent and solvent. It has antimicrobial properties.
  • Molecular weight: 154.25
  • Formula: C10H18O
  • CLOGP: 2.83
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 0
  • TPSA: 9.23
  • ALOGS: -3.84
  • ROTB: 0

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System

None

Pharmacologic Action:

SourceCodeDescription
ATC R05CA13 RESPIRATORY SYSTEM
COUGH AND COLD PREPARATIONS
EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
Expectorants
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000996 Antitussive Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D003358 Cosmetics
MeSH PA D005421 Flavoring Agents
MeSH PA D005503 Food Additives
MeSH PA D007302 Insect Repellents
MeSH PA D009067 Mouthwashes
MeSH PA D010575 Pesticides
MeSH PA D010592 Pharmaceutic Aids
MeSH PA D020011 Protective Agents
MeSH PA D019141 Respiratory System Agents
CHEBI has role CHEBI:35617 flavouring agent
MeSH PA D012997 Solvents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D000077591 MESH_DESCRIPTOR_UI
4019135 VUID
N0000179082 NUI
C0055738 UMLSCUI
D04115 KEGG_DRUG
21116 RXNORM
4019135 VANDF
NOCODE MMSL
002583 NDDF
259119007 SNOMEDCT_US
CHEMBL485259 ChEMBL_ID
RV6J6604TK UNII
DB03852 DRUGBANK_ID
CHEBI:27961 CHEBI
2758 PUBCHEM_CID
2464 IUPHAR_LIGAND_ID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Tartar Control Plus HUMAN OTC DRUG LABEL 4 0363-0045 MOUTHWASH 0.92 mg ORAL OTC monograph not final 15 sections
Antispetic HUMAN OTC DRUG LABEL 4 0363-0080 MOUTHWASH 0.92 mg ORAL OTC monograph not final 12 sections
Rinse HUMAN OTC DRUG LABEL 4 0363-0318 MOUTHWASH 0.92 mg ORAL OTC monograph not final 14 sections
Tartar control plus HUMAN OTC DRUG LABEL 4 0363-0434 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Antispetic HUMAN OTC DRUG LABEL 4 0363-0664 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Tartar control plus HUMAN OTC DRUG LABEL 4 0363-0855 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Antiseptic HUMAN OTC DRUG LABEL 4 0869-0072 MOUTHWASH 0.92 mg ORAL OTC monograph not final 12 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 0869-0318 MOUTHWASH 0.92 mg ORAL OTC monograph not final 10 sections
Tartar Control Plus HUMAN OTC DRUG LABEL 4 0869-0434 MOUTHWASH 0.92 mg ORAL OTC monograph not final 12 sections
Antispetic HUMAN OTC DRUG LABEL 4 0869-0664 MOUTHWASH 0.92 mg ORAL OTC monograph not final 12 sections
Antispetic HUMAN OTC DRUG LABEL 4 10202-664 MOUTHWASH 0.92 mg ORAL OTC monograph not final 12 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 11344-072 MOUTHWASH 0.09 kg ORAL OTC monograph not final 8 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 11344-318 MOUTHWASH 0.09 kg ORAL OTC monograph not final 10 sections
Antispetic HUMAN OTC DRUG LABEL 4 11673-072 MOUTHWASH 0.92 mg ORAL OTC monograph not final 12 sections
Antiseptic HUMAN OTC DRUG LABEL 4 11673-318 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Tartar control plus HUMAN OTC DRUG LABEL 4 11673-434 MOUTHWASH 0.92 mg ORAL OTC monograph not final 12 sections
Antispetic HUMAN OTC DRUG LABEL 4 11673-664 MOUTHWASH 0.92 mg ORAL OTC monograph not final 12 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 11822-0072 MOUTHWASH 0.92 mg ORAL OTC monograph not final 9 sections
Tartar control plus HUMAN OTC DRUG LABEL 4 11822-0434 MOUTHWASH 0.92 mg ORAL OTC monograph not final 11 sections
Antispetic HUMAN OTC DRUG LABEL 4 11822-0664 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Oral Care Antiseptic HUMAN OTC DRUG LABEL 4 11822-3108 MOUTHWASH 0.92 mg ORAL OTC monograph not final 12 sections
Tartar control plus HUMAN OTC DRUG LABEL 4 11822-5829 MOUTHWASH 0.92 mg ORAL OTC monograph not final 12 sections
Tartar Control Plus HUMAN OTC DRUG LABEL 4 11822-8787 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Antispetic HUMAN OTC DRUG LABEL 4 15127-318 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Mastic Dent HUMAN OTC DRUG LABEL 4 15304-4085 MOUTHWASH 0.92 mg ORAL OTC monograph not final 10 sections
Antispetic HUMAN OTC DRUG LABEL 4 21130-072 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 21130-318 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Antispetic HUMAN OTC DRUG LABEL 4 21130-664 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Mouth Rinse HUMAN OTC DRUG LABEL 4 30142-072 MOUTHWASH 0.92 mg ORAL OTC monograph not final 13 sections
Antiseptic Mouth Rinse HUMAN OTC DRUG LABEL 4 30142-318 MOUTHWASH 0.92 mg ORAL OTC monograph not final 14 sections