cineole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4259 | 470-82-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A monoterpene and cyclohexanol derivative that is the major component of EUCALYPTUS OIL. It is used in mouthwash, insect repellent, and as a cough suppressant, and also is widely used as a flavoring agent and solvent. It has antimicrobial properties.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Dyspnoea | 43.28 | 34.91 | 34 | 346 | 376748 | 34579803 |
| Product prescribing error | 42.90 | 34.91 | 14 | 366 | 22913 | 34933638 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Product prescribing error | 47.93 | 27.39 | 17 | 670 | 44796 | 79698905 |
| Dyspnoea | 35.77 | 27.39 | 40 | 647 | 856985 | 78886716 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | R05CA13 | RESPIRATORY SYSTEM COUGH AND COLD PREPARATIONS EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS Expectorants |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000996 | Antitussive Agents |
| MeSH PA | D002491 | Central Nervous System Agents |
| MeSH PA | D003358 | Cosmetics |
| MeSH PA | D005421 | Flavoring Agents |
| MeSH PA | D005503 | Food Additives |
| MeSH PA | D007302 | Insect Repellents |
| MeSH PA | D009067 | Mouthwashes |
| MeSH PA | D010575 | Pesticides |
| MeSH PA | D010592 | Pharmaceutic Aids |
| MeSH PA | D020011 | Protective Agents |
| MeSH PA | D019141 | Respiratory System Agents |
| MeSH PA | D012997 | Solvents |
| CHEBI has role | CHEBI:35617 | flavouring agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4019135 | VUID |
| N0000179082 | NUI |
| D04115 | KEGG_DRUG |
| 4019135 | VANDF |
| CHEBI:27961 | CHEBI |
| CHEMBL485259 | ChEMBL_ID |
| 2464 | IUPHAR_LIGAND_ID |
| DB03852 | DRUGBANK_ID |
| 21116 | RXNORM |
| NOCODE | MMSL |
| 002583 | NDDF |
| 259119007 | SNOMEDCT_US |
| C0055738 | UMLSCUI |
| D000077591 | MESH_DESCRIPTOR_UI |
| CNL | PDB_CHEM_ID |
| 2758 | PUBCHEM_CID |
| RV6J6604TK | UNII |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Antiseptic Mouth Rinse | HUMAN OTC DRUG LABEL | 4 | 0363-0072 | MOUTHWASH | 0.09 kg | ORAL | OTC monograph not final | 12 sections |
| Antiseptic Mouth Rinse | HUMAN OTC DRUG LABEL | 4 | 0363-0072 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 12 sections |
| Rinse | HUMAN OTC DRUG LABEL | 4 | 0363-0318 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 14 sections |
| Rinse | HUMAN OTC DRUG LABEL | 4 | 0363-0318 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 14 sections |
| Rinse | HUMAN OTC DRUG LABEL | 4 | 0363-0318 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 14 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 0363-0664 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 15 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 0363-0664 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 15 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 0363-0664 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 15 sections |
| Tartar control plus | HUMAN OTC DRUG LABEL | 4 | 0363-0855 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Antiseptic | HUMAN OTC DRUG LABEL | 4 | 0869-0072 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 12 sections |
| Antiseptic | HUMAN OTC DRUG LABEL | 4 | 0869-0072 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 12 sections |
| Antiseptic Mouth Rinse | HUMAN OTC DRUG LABEL | 4 | 0869-0318 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Antiseptic Mouth Rinse | HUMAN OTC DRUG LABEL | 4 | 0869-0318 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Antiseptic Mouth Rinse | HUMAN OTC DRUG LABEL | 4 | 0869-0318 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Tartar Control Plus | HUMAN OTC DRUG LABEL | 4 | 0869-0434 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 12 sections |
| Tartar Control Plus | HUMAN OTC DRUG LABEL | 4 | 0869-0434 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 12 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 0869-0664 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 0869-0664 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 0869-0664 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Tartar control plus | HUMAN OTC DRUG LABEL | 4 | 0869-0855 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 11 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 10202-664 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 12 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 10202-664 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 12 sections |
| Antiseptic Mouth Rinse | HUMAN OTC DRUG LABEL | 4 | 11344-072 | MOUTHWASH | 0.09 kg | ORAL | OTC monograph not final | 12 sections |
| Antiseptic Mouth Rinse | HUMAN OTC DRUG LABEL | 4 | 11344-318 | MOUTHWASH | 0.09 kg | ORAL | OTC monograph not final | 13 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 11344-567 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 11344-567 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 11673-072 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Antispetic | HUMAN OTC DRUG LABEL | 4 | 11673-072 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Antiseptic | HUMAN OTC DRUG LABEL | 4 | 11673-318 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |
| Antiseptic | HUMAN OTC DRUG LABEL | 4 | 11673-318 | MOUTHWASH | 0.92 mg | ORAL | OTC monograph not final | 13 sections |