thymol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4258	89-83-8

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: thymol thyme camphor thymol chrystals	A phenol obtained from thyme oil or other volatile oils used as a stabilizer in pharmaceutical preparations, and as an antiseptic (antibacterial or antifungal) agent. Molecular weight: 150.22 Formula: C10H14O CLOGP: 3.20 LIPINSKI: 0 HAC: 1 HDO: 1 TPSA: 20.23 ALOGS: -2.37 ROTB: 1

Molecule

Description

Molfile Inchi Smiles

Synonyms:

thymol
thyme camphor
thymol chrystals

A phenol obtained from thyme oil or other volatile oils used as a stabilizer in pharmaceutical preparations, and as an antiseptic (antibacterial or antifungal) agent.

Molecular weight: 150.22
Formula: C10H14O
CLOGP: 3.20
LIPINSKI: 0
HAC: 1
HDO: 1
TPSA: 20.23
ALOGS: -2.37
ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000891	Anti-Infective Agents, Local
MeSH PA	D000935	Antifungal Agents
CHEBI has role	CHEBI:27311	essential oil component

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	10.57	acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Type	Activity value (-log[M])	Bioact source
Transient receptor potential cation channel subfamily A member 1	Ion channel	O75762	TRPA1_HUMAN	EC50	5.22	CHEMBL
Transient receptor potential cation channel subfamily M member 8	Ion channel		TRPM8_RAT	EC50	4.28	CHEMBL
Heat sensitive channel TRPV3	Unclassified		Q4QYD9_RAT	EC50	4.54	CHEMBL

External reference:

ID	Source
4019136	VUID
N0000147386	NUI
D01039	KEGG_DRUG
4019136	VANDF
C0040096	UMLSCUI
CHEBI:27607	CHEBI
IPB	PDB_CHEM_ID
CHEMBL29411	ChEMBL_ID
D013943	MESH_DESCRIPTOR_UI
DB02513	DRUGBANK_ID
2499	IUPHAR_LIGAND_ID
3J50XA376E	UNII
6989	PUBCHEM_CID
10553	RXNORM
NOCODE	MMSL
002914	NDDF
331322007	SNOMEDCT_US
54932001	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Antiseptic Mouth Rinse	HUMAN OTC DRUG LABEL	4	0363-0072	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	12 sections
Antiseptic Mouth Rinse	HUMAN OTC DRUG LABEL	4	0363-0072	MOUTHWASH	0.06 kg	ORAL	OTC monograph not final	12 sections
Rinse	HUMAN OTC DRUG LABEL	4	0363-0318	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	14 sections
Rinse	HUMAN OTC DRUG LABEL	4	0363-0318	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	14 sections
Rinse	HUMAN OTC DRUG LABEL	4	0363-0318	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	14 sections
Antispetic	HUMAN OTC DRUG LABEL	4	0363-0664	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	15 sections
Antispetic	HUMAN OTC DRUG LABEL	4	0363-0664	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	15 sections
Antispetic	HUMAN OTC DRUG LABEL	4	0363-0664	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	15 sections
Tartar control plus	HUMAN OTC DRUG LABEL	4	0363-0855	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Antiseptic	HUMAN OTC DRUG LABEL	4	0869-0072	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	12 sections
Antiseptic	HUMAN OTC DRUG LABEL	4	0869-0072	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	12 sections
Antiseptic Mouth Rinse	HUMAN OTC DRUG LABEL	4	0869-0318	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Antiseptic Mouth Rinse	HUMAN OTC DRUG LABEL	4	0869-0318	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Antiseptic Mouth Rinse	HUMAN OTC DRUG LABEL	4	0869-0318	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Tartar Control Plus	HUMAN OTC DRUG LABEL	4	0869-0434	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	12 sections
Tartar Control Plus	HUMAN OTC DRUG LABEL	4	0869-0434	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	12 sections
Antispetic	HUMAN OTC DRUG LABEL	4	0869-0664	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Antispetic	HUMAN OTC DRUG LABEL	4	0869-0664	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Antispetic	HUMAN OTC DRUG LABEL	4	0869-0664	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Tartar control plus	HUMAN OTC DRUG LABEL	4	0869-0855	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	11 sections
Antispetic	HUMAN OTC DRUG LABEL	4	10202-664	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	12 sections
Antispetic	HUMAN OTC DRUG LABEL	4	10202-664	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	12 sections
Antiseptic Mouth Rinse	HUMAN OTC DRUG LABEL	4	11344-072	MOUTHWASH	0.06 kg	ORAL	OTC monograph not final	12 sections
Antiseptic Mouth Rinse	HUMAN OTC DRUG LABEL	4	11344-318	MOUTHWASH	0.06 kg	ORAL	OTC monograph not final	13 sections
Antispetic	HUMAN OTC DRUG LABEL	4	11344-567	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Antispetic	HUMAN OTC DRUG LABEL	4	11344-567	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Antispetic	HUMAN OTC DRUG LABEL	4	11673-072	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Antispetic	HUMAN OTC DRUG LABEL	4	11673-072	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Antiseptic	HUMAN OTC DRUG LABEL	4	11673-318	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections
Antiseptic	HUMAN OTC DRUG LABEL	4	11673-318	MOUTHWASH	0.64 mg	ORAL	OTC monograph not final	13 sections