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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
magnesium hydroxide 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
4244
1309-42-8
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
magnesium hydroxide
An inorganic compound that occurs in nature as the mineral brucite. It acts as an antacid with cathartic effects.
Molecular weight: 58.32
Formula: H2MgO2
CLOGP: -1.75
LIPINSKI: None
HAC: 2
HDO: 2
TPSA: 40.46
ALOGS:
ROTB: 0
Drug dosage:
Dose
Unit
Route
3
g
O
0.50
g
O
ADMET properties:
None
Approvals:
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Date
Agency
Company
Orphan
Oct. 16, 2000
FDA
MCNEIL CONS
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FDA Adverse Event Reporting System (Female)
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MedDRA adverse event term
Likelihood ratio
Likelihood ratio threshold
Patients taking drug having adverse event
Patients taking drug not having adverse event
Patients not taking drug having adverse event
Patients not taking drug not having adverse event
Sedation complication
736.83
11.12
309
49663
13513
63425537
Creatinine renal clearance decreased
690.86
11.12
310
49662
15998
63423052
Orthostatic hypotension
668.52
11.12
393
49579
35767
63403283
Cognitive disorder
642.56
11.12
450
49522
55365
63383685
Sedation
627.48
11.12
387
49585
38422
63400628
Blood calcium decreased
598.10
11.12
328
49644
26123
63412927
Balance disorder
503.85
11.12
463
49509
83959
63355091
Toxicity to various agents
445.99
11.12
740
49232
246510
63192540
Depressed level of consciousness
382.99
11.12
347
49625
61731
63377319
Hypotension
355.46
11.12
709
49263
271895
63167155
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FDA Adverse Event Reporting System (Male)
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MedDRA adverse event term
Likelihood ratio
Likelihood ratio threshold
Patients taking drug having adverse event
Patients taking drug not having adverse event
Patients not taking drug having adverse event
Patients not taking drug not having adverse event
Toxicity to various agents
203.27
13.10
358
16906
200004
34739663
Drug abuse
133.99
13.10
202
17062
98894
34840773
Infusion related reaction
107.96
13.10
132
17132
52925
34886742
Oxygen saturation decreased
70.19
13.10
108
17156
53710
34885957
Blood pressure increased
69.75
13.10
142
17122
87960
34851707
Blood pressure fluctuation
56.53
13.10
66
17198
25183
34914484
Heart rate decreased
55.06
13.10
73
17191
31672
34907995
Rheumatoid arthritis
43.33
13.10
72
17192
38166
34901501
Nasopharyngitis
32.74
13.10
92
17172
69876
34869791
Blood pressure diastolic decreased
27.75
13.10
28
17236
9066
34930601
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FDA Adverse Event Reporting System (Geriatric)
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MedDRA adverse event term
Likelihood ratio
Likelihood ratio threshold
Patients taking drug having adverse event
Patients taking drug not having adverse event
Patients not taking drug having adverse event
Patients not taking drug not having adverse event
Sedation complication
759.00
11.22
321
58388
15348
79670331
Creatinine renal clearance decreased
699.53
11.22
321
58388
18681
79666998
Cognitive disorder
611.33
11.22
465
58244
69461
79616218
Blood calcium decreased
588.47
11.22
338
58371
31481
79654198
Toxicity to various agents
580.98
11.22
1079
57630
420461
79265218
Sedation
566.97
11.22
395
58314
51500
79634179
Orthostatic hypotension
550.22
11.22
400
58309
55764
79629915
Balance disorder
475.21
11.22
467
58242
98390
79587289
Infusion related reaction
371.06
11.22
632
58077
229605
79456074
Depressed level of consciousness
320.21
11.22
375
58334
96277
79589402
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FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
A02AA04
ALIMENTARY TRACT AND METABOLISM
DRUGS FOR ACID RELATED DISORDERS
ANTACIDS
Magnesium compounds
ATC
G04BX01
GENITO URINARY SYSTEM AND SEX HORMONES
UROLOGICALS
UROLOGICALS
Other urologicals
CHEBI has role
CHEBI:65265
antacids
CHEBI has role
CHEBI:79314
flame retardants
MeSH PA
D000863
Antacids
MeSH PA
D005765
Gastrointestinal Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Peptic ulcer
indication
13200003
DOID:750
Constipation
indication
14760008
DOID:2089
Heartburn
indication
16331000
Indigestion
indication
162031009
Gastroesophageal reflux disease
indication
235595009
DOID:8534
Incomplete passage of stool
indication
249515001
Gastric Hypersecretory Conditions
indication
Heartburn Prevention
indication
Hiatal Hernia with Reflux Esophagitis
indication
Hypocalcemia
off-label use
5291005
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
001119
NDDF
001186
NDDF
387337001
SNOMEDCT_US
4017693
VUID
4017693
VANDF
5013
MMSL
5579
MMSL
60468008
SNOMEDCT_US
6581
RXNORM
73981
PUBCHEM_CID
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
basic care dual action complete
HUMAN OTC DRUG LABEL
3
0113-7321
TABLET, CHEWABLE
165 mg
ORAL
ANDA
15 sections
basic care dual action complete
HUMAN OTC DRUG LABEL
3
0113-7321
TABLET, CHEWABLE
165 mg
ORAL
ANDA
15 sections
basic care milk of magnesia
HUMAN OTC DRUG LABEL
1
0113-7332
SUSPENSION
1200 mg
ORAL
OTC monograph not final
14 sections
basic care milk of magnesia
HUMAN OTC DRUG LABEL
1
0113-7332
SUSPENSION
1200 mg
ORAL
OTC monograph not final
14 sections
Good Sense antacid
HUMAN OTC DRUG LABEL
3
0113-0340
SUSPENSION
800 mg
ORAL
OTC monograph final
13 sections
Good Sense antacid
HUMAN OTC DRUG LABEL
3
0113-0340
SUSPENSION
800 mg
ORAL
OTC monograph final
13 sections
good sense antacid
HUMAN OTC DRUG LABEL
3
0113-0851
SUSPENSION
400 mg
ORAL
OTC monograph final
13 sections
good sense antacid
HUMAN OTC DRUG LABEL
3
0113-0851
SUSPENSION
400 mg
ORAL
OTC monograph final
13 sections
Good Sense AntacidMaximum Strength
HUMAN OTC DRUG LABEL
3
0113-0588
SUSPENSION
800 mg
ORAL
OTC monograph final
13 sections
Good Sense AntacidMaximum Strength
HUMAN OTC DRUG LABEL
3
0113-0588
SUSPENSION
800 mg
ORAL
OTC monograph final
13 sections
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Structure 🔎
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Smart API
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L1000
FAQ
magnesium hydroxide