oxygen 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4235	7782-44-7

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: oxygen molecular oxygen oxygen molecule oxygen, usp	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. Molecular weight: 32.00 Formula: O2 CLOGP: LIPINSKI: None HAC: 2 HDO: 0 TPSA: 34.14 ALOGS: ROTB: 0

Molecule

Description

Molfile Inchi Smiles

Synonyms:

oxygen
molecular oxygen
oxygen molecule
oxygen, usp

An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.

Molecular weight: 32.00
Formula: O2
CLOGP:
LIPINSKI: None
HAC: 2
HDO: 0
TPSA: 34.14
ALOGS:
ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Dyspnoea	933.44	11.56	1976	58270	659337	62769439
Pulmonary arterial hypertension	715.14	11.56	373	59873	22204	63406572
Oxygen saturation decreased	608.99	11.56	571	59675	88014	63340762
Pulmonary hypertension	533.93	11.56	369	59877	36754	63392022
Oxygen consumption increased	477.59	11.56	168	60078	3716	63425060
Right ventricular failure	457.40	11.56	253	59993	16935	63411841
Dyspnoea exertional	401.32	11.56	382	59864	59920	63368856
Fluid retention	376.25	11.56	367	59879	59319	63369457
Drug ineffective	365.49	11.56	277	59969	1044488	62384288
Chronic obstructive pulmonary disease	305.87	11.56	336	59910	62350	63366426

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FDA Adverse Event Reporting System (Male)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Dyspnoea	362.12	12.42	917	29385	375865	34550764
Oxygen saturation decreased	344.09	12.42	320	29982	53498	34873131
Pulmonary arterial hypertension	311.77	12.42	152	30150	8587	34918042
Hypoxia	246.29	12.42	270	30032	54825	34871804
Right ventricular failure	205.02	12.42	115	30187	8669	34917960
Oxygen consumption increased	176.76	12.42	60	30242	1306	34925323
Pulmonary hypertension	166.55	12.42	141	30161	20783	34905846
Respiratory failure	152.04	12.42	308	29994	108264	34818365
Chronic obstructive pulmonary disease	139.23	12.42	191	30111	48727	34877902
Pneumonia	117.73	12.42	621	29681	362006	34564623

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FDA Adverse Event Reporting System (Geriatric)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Dyspnoea	1034.98	10.86	2458	75855	854567	78811508
Pulmonary arterial hypertension	941.34	10.86	489	77824	27877	79638198
Oxygen saturation decreased	794.44	10.86	795	77518	128252	79537823
Pulmonary hypertension	606.01	10.86	447	77866	47633	79618442
Oxygen consumption increased	588.52	10.86	211	78102	4768	79661307
Right ventricular failure	568.93	10.86	329	77984	23168	79642907
Fluid retention	469.98	10.86	452	77861	69357	79596718
Hypoxia	459.13	10.86	536	77777	102707	79563368
Dyspnoea exertional	412.27	10.86	467	77846	86606	79579469
Respiratory failure	313.93	10.86	604	77709	180307	79485768

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FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

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Source	Code	Description
ATC	V03AN01	VARIOUS ALL OTHER THERAPEUTIC PRODUCTS ALL OTHER THERAPEUTIC PRODUCTS Medical gases
CHEBI has role	CHEBI:27027	trace elements
CHEBI has role	CHEBI:33284	nutrients
CHEBI has role	CHEBI:33893	reagent
CHEBI has role	CHEBI:35472	anti-inflammatory drugs
CHEBI has role	CHEBI:63248	oxidizer
CHEBI has role	CHEBI:75772	S. cerevisiae metabolites
CHEBI has role	CHEBI:77746	Homo sapiens metabolite
CHEBI has role	CHEBI:77974	food packaging gases
CHEBI has role	CHEBI:33937	macronutrients

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Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

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🐶 Veterinary products

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Product	Applicant	Ingredients
None (Med Gas)	Air Liquide Industrial U.S. L.P.	2
None (Med Gas)	Air Liquide Large Industries U.S. L.P.	2
None (Med Gas)	Messer LLC	2
None (Med Gas)	Messer Canada Inc.	2
None (Med Gas)	Messer Gas Puerto Rico Inc.	2
None (Med Gas)	Norco Inc.	2
None (Med Gas)	Airgas Merchant Gases LLC	2
None (Med Gas)	Praxair Inc.	2
None (Med Gas)	Aspen Air, US Corp	2
None (Med Gas)	Air Products and Chemicals Inc.	2

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Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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ID	Source
WEQ	PDB_CHEM_ID
000826	NDDF
24099007	SNOMEDCT_US
4019105	VUID
4019105	VANDF
767111007	SNOMEDCT_US
7806	RXNORM
977	PUBCHEM_CID
C0184633	UMLSCUI
CHEBI:25805	CHEBI

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Pharmaceutical products:

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Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
AIR COMPRESSED	HUMAN PRESCRIPTION DRUG LABEL	1	10167-600	GAS	20 L	RESPIRATORY (INHALATION)	NDA	1 sections
AIR COMPRESSED	HUMAN PRESCRIPTION DRUG LABEL	1	10167-600	GAS	20 L	RESPIRATORY (INHALATION)	NDA	1 sections
HELIOX	HUMAN PRESCRIPTION DRUG LABEL	1	10006-009	GAS	20 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
HELIOX	HUMAN PRESCRIPTION DRUG LABEL	1	10006-010	GAS	25 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
HELIOX	HUMAN PRESCRIPTION DRUG LABEL	1	10006-011	GAS	30 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
MEDICAL AIR	HUMAN PRESCRIPTION DRUG LABEL	1	10006-004	GAS	21 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
OXYGEN	HUMAN PRESCRIPTION DRUG LABEL	1	10006-001	GAS	99 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10014-001	GAS	990 mL	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10014-001	GAS	990 mL	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10018-8999	GAS	990 mL	RESPIRATORY (INHALATION)	NDA	1 sections

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