acetic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4211 64-19-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • acetic acid
  • acetic acid, glacial
  • ethanoic acid
  • ethylic acid
  • vinegar acid
Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
  • Molecular weight: 60.05
  • Formula: C2H4O2
  • CLOGP: -0.19
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 37.30
  • ALOGS: 0.73
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
May 17, 1960 FDA HI TECH PHARMA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC G01AD02 GENITO URINARY SYSTEM AND SEX HORMONES
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Organic acids
ATC S02AA10 SENSORY ORGANS
OTOLOGICALS
ANTIINFECTIVES
Antiinfectives
CHEBI has role CHEBI:48356 protogenic solvent
CHEBI has role CHEBI:64049 pH control agents
CHEBI has role CHEBI:65256 antimicrobial food preservatives
CHEBI has role CHEBI:83056 Daphnia magna metabolites
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D007202 Indicators and Reagents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Otitis externa indication 3135009
Otalgia off-label use 16001004
Impacted cerumen off-label use 18070006
Otitis Externa Eczema off-label use
Otitis Externa Seborrhea off-label use
Herpes zoster auricularis contraindication 21954000 DOID:9210
Perforation of tympanic membrane contraindication 60442001
Herpes simplex contraindication 88594005 DOID:8566
Tuberculosis of ear contraindication 186269001
Viral ear infection contraindication 312137007
Fungal ear infection contraindication 312148000
Infective otitis media contraindication 312218008
Porphyria contraindication 418470004
Sensation Disturbance of Genitals contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.44 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Tyrosine-protein kinase Lck Kinase Kd 6.19 CHEMBL
Tyrosine-protein kinase Fyn Kinase Kd 6.05 CHEMBL
Free fatty acid receptor 2 GPCR AGONIST EC50 4.60 IUPHAR
Free fatty acid receptor 3 GPCR EC50 4.92 CHEMBL

External reference:

IDSource
4018456 VUID
N0000146780 NUI
D00010 KEGG_DRUG
4017443 VANDF
4018456 VANDF
C0000983 UMLSCUI
CHEBI:15366 CHEBI
ACY PDB_CHEM_ID
CHEMBL539 ChEMBL_ID
D019342 MESH_DESCRIPTOR_UI
DB03166 DRUGBANK_ID
1058 IUPHAR_LIGAND_ID
Q40Q9N063P UNII
176 PUBCHEM_CID
168 RXNORM
11539 MMSL
4122 MMSL
822 MMSL
9812 MMSL
d04228 MMSL
002875 NDDF
002917 NDDF
2869004 SNOMEDCT_US
326289007 SNOMEDCT_US
422082008 SNOMEDCT_US
772941001 SNOMEDCT_US
786281009 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 0264-2304 IRRIGANT 0.25 g IRRIGATION NDA 21 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 0264-2304 IRRIGANT 0.25 g IRRIGATION NDA 21 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 0338-0656 IRRIGANT 250 mg IRRIGATION NDA 14 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 0338-0656 IRRIGANT 250 mg IRRIGATION NDA 14 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 0409-6143 IRRIGANT 250 mg IRRIGATION NDA 12 sections
Fem pH HUMAN PRESCRIPTION DRUG LABEL 2 0813-0799 JELLY 0.01 g VAGINAL unapproved drug other 18 sections
Fem pH HUMAN PRESCRIPTION DRUG LABEL 2 0813-0799 JELLY 0.01 g VAGINAL unapproved drug other 18 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 0990-6143 IRRIGANT 250 mg IRRIGATION NDA 12 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 0990-6143 IRRIGANT 250 mg IRRIGATION NDA 12 sections
acetic acid HUMAN PRESCRIPTION DRUG LABEL 1 21695-222 SOLUTION 20.65 mg AURICULAR (OTIC) NDA 11 sections
acetic acid HUMAN PRESCRIPTION DRUG LABEL 1 50090-0351 SOLUTION 20.65 mg AURICULAR (OTIC) NDA 10 sections
acetic acid HUMAN PRESCRIPTION DRUG LABEL 1 50090-0351 SOLUTION 20.65 mg AURICULAR (OTIC) NDA 10 sections
Acetic Acid Human Prescription Drug Label 1 50090-6263 SOLUTION 20 mg AURICULAR (OTIC) ANDA 12 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 50090-6527 SOLUTION 20.65 mg AURICULAR (OTIC) ANDA 12 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 50383-889 SOLUTION 20.65 mg AURICULAR (OTIC) NDA 10 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 50383-889 SOLUTION 20.65 mg AURICULAR (OTIC) NDA 10 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 50383-889 SOLUTION 20.65 mg AURICULAR (OTIC) NDA 10 sections
hydrocortisone and acetic acid HUMAN PRESCRIPTION DRUG LABEL 2 50383-901 SOLUTION 20.75 mg AURICULAR (OTIC) NDA 13 sections
hydrocortisone and acetic acid HUMAN PRESCRIPTION DRUG LABEL 2 50383-901 SOLUTION 20.75 mg AURICULAR (OTIC) NDA 13 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 50436-4600 SOLUTION 20 mg AURICULAR (OTIC) ANDA 11 sections
Hydrocortisone and Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 2 51672-3007 SOLUTION 20.80 mg AURICULAR (OTIC) ANDA 13 sections
RELEGARD HUMAN PRESCRIPTION DRUG LABEL 2 51674-0130 GEL 0.90 mg TOPICAL unapproved drug other 3 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 52817-816 SOLUTION 20.65 mg AURICULAR (OTIC) ANDA 12 sections
acetic acid HUMAN PRESCRIPTION DRUG LABEL 1 55045-1243 SOLUTION 20.65 mg AURICULAR (OTIC) NDA 11 sections
acetic acid HUMAN PRESCRIPTION DRUG LABEL 1 55700-424 SOLUTION 20.65 mg AURICULAR (OTIC) NDA 11 sections
acetic acid HUMAN PRESCRIPTION DRUG LABEL 1 55700-424 SOLUTION 20.65 mg AURICULAR (OTIC) NDA 11 sections
Fever Reliever HUMAN OTC DRUG LABEL 16 57955-0160 LIQUID 10 [hp_X] ORAL unapproved homeopathic 9 sections
ACETIC ACID HUMAN PRESCRIPTION DRUG LABEL 1 60432-741 SOLUTION 20 mg AURICULAR (OTIC) ANDA 11 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 64980-424 SOLUTION 20 mg AURICULAR (OTIC) ANDA 12 sections
Acetic Acid HUMAN PRESCRIPTION DRUG LABEL 1 64980-424 SOLUTION 20 mg AURICULAR (OTIC) ANDA 12 sections