budralazine indications/contra

Stem definitionDrug idCAS RN
antihypertensives, hydrazinephthalazine derivatives 421 36798-79-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • budralazine
  • buterazine
  • budralazine monohydrochloride
  • budralazine hydrochloride
  • budralazine HCl
  • Molecular weight: 240.31
  • Formula: C14H16N4
  • CLOGP: 2.70
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 49.11
  • ALOGS: -3.68
  • ROTB: 2

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
MeSH PA D000959 Antihypertensive Agents
MeSH PA D002317 Cardiovascular Agents
MeSH PA D014665 Vasodilator Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.92 Basic
pKa2 3.95 Basic
pKa3 1.56 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
D01997 KEGG_DRUG
6419536 PUBCHEM_CID
CHEBI:134979 CHEBI
C006153 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL2107516 ChEMBL_ID
S0177QHV2B UNII
3750 INN_ID

Pharmaceutical products:

None