nadide Indications/Contra | FAERs | Orange Book | BioActivity |

Stem definitionDrug idCAS RN
4140 53-84-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • nicotinamide adenine
  • coenzyme I
  • nadide
  • nicotinamide adenine dinucleotide
  • NAD
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
  • Molecular weight: 663.43
  • Formula: C21H27N7O14P2
  • CLOGP: -7.80
  • LIPINSKI: 3
  • HAC: 21
  • HDO: 7
  • TPSA: 321.09
  • ALOGS: -2.52
  • ROTB: 11

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 0.04 acidic
pKa2 2.08 acidic
pKa3 11.94 acidic
pKa4 12.72 acidic
pKa5 12.84 acidic
pKa6 13.47 acidic
pKa7 13.84 acidic
pKa8 3.95 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000170823 NUI
C0027270 UMLSCUI
D00002 KEGG_DRUG
0U46U6E8UK UNII
2371 INN_ID
1044975 RXNORM
008958 NDDF
CHEBI:15846 CHEBI
CHEMBL1234613 ChEMBL_ID
D009243 MESH_DESCRIPTOR_UI
DB14128 DRUGBANK_ID
5892 PUBCHEM_CID
2451 IUPHAR_LIGAND_ID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Bonogen HUMAN OTC DRUG LABEL 3 50653-1001 SHAMPOO 0.30 g TOPICAL unapproved drug other 1 sections
Bonogen Plus HUMAN OTC DRUG LABEL 3 50653-2001 SHAMPOO 0.30 g TOPICAL unapproved drug other 1 sections
Born Hair HUMAN OTC DRUG LABEL 3 50653-4001 SHAMPOO 0.30 g TOPICAL unapproved drug other 7 sections
Viatrexx-Arthros HUMAN PRESCRIPTION DRUG LABEL 4 73069-035 INJECTION 31 [kp_C] INTRAVENOUS unapproved drug other 11 sections
Viatrexx-Mesenchyme HUMAN PRESCRIPTION DRUG LABEL 9 73069-102 INJECTION 31 [kp_C] INTRAVENOUS unapproved drug other 11 sections
Viatrexx-Prolo HUMAN PRESCRIPTION DRUG LABEL 12 73069-443 INJECTION 31 [kp_C] INTRAVENOUS unapproved drug other 11 sections