bucillamine indications/contra

Stem definitionDrug idCAS RN
414 65002-17-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bucillamine
  • rimatil
  • thiobutarit
  • tiobutarit
  • Molecular weight: 223.31
  • Formula: C7H13NO3S2
  • CLOGP: 0.36
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 66.40
  • ALOGS: -2.54
  • ROTB: 4

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

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MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Interstitial lung disease 147.87 87.88 31 142 13985 3371701

Pharmacologic Action:

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SourceCodeDescription
ATC M01CC02 MUSCULO-SKELETAL SYSTEM
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
SPECIFIC ANTIRHEUMATIC AGENTS
Penicillamine and similar agents
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D000975 Antioxidants
MeSH PA D018501 Antirheumatic Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D020011 Protective Agents
MeSH PA D018689 Sensory System Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.2 acidic
pKa2 8.46 acidic
pKa3 9.51 acidic
pKa4 13.13 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
D01809 KEGG_DRUG
656604 PUBCHEM_CID
CHEBI:31312 CHEBI
C026535 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL2104131 ChEMBL_ID
R80LRA5WTF UNII
5683 INN_ID
DB12160 DRUGBANK_ID

Pharmaceutical products:

None