valine Indications/Contra | FAERs | Orange Book | BioActivity |

Stem definitionDrug idCAS RN
4128 72-18-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • valine
  • L-valine
A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
  • Molecular weight: 117.15
  • Formula: C5H11NO2
  • CLOGP: -2.29
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 63.32
  • ALOGS: 0.26
  • ROTB: 2

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Parenteral nutrition associated liver disease 530.92 54.62 50 180 0 3385629
Foetal growth restriction 85.66 54.62 15 215 1854 3383775

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:50733 nutraceutical

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.49 acidic
pKa2 9.85 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
DB00161 DRUGBANK_ID
4018679 VUID
N0000146990 NUI
C0042285 UMLSCUI
4794 IUPHAR_LIGAND_ID
D00039 KEGG_DRUG
CHEMBL43068 ChEMBL_ID
11115 RXNORM
4018679 VANDF
NOCODE MMSL
419086006 SNOMEDCT_US
72840006 SNOMEDCT_US
N0000006239 NDFRT
N0000146990 NDFRT
003652 NDDF
236409 MMSL
15494 MMSL
d08094 MMSL
6287 PUBCHEM_CID
HG18B9YRS7 UNII
6175 INN_ID
D014633 MESH_DESCRIPTOR_UI
CHEBI:16414 CHEBI

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
NephrAmine HUMAN PRESCRIPTION DRUG LABEL 10 0264-1909 INJECTION, SOLUTION 0.64 g INTRAVENOUS NDA 13 sections
ProcalAmine HUMAN PRESCRIPTION DRUG LABEL 22 0264-1915 INJECTION 0.20 g INTRAVENOUS NDA 13 sections
Plenamine HUMAN PRESCRIPTION DRUG LABEL 17 0264-3200 SOLUTION 960 mg INTRAVENOUS ANDA 13 sections
Plenamine HUMAN PRESCRIPTION DRUG LABEL 17 0264-3205 SOLUTION 960 mg INTRAVENOUS ANDA 13 sections
FreAmine III HUMAN PRESCRIPTION DRUG LABEL 16 0264-9010 INJECTION, SOLUTION 0.66 g INTRAVENOUS NDA 13 sections
FreAmine III HUMAN PRESCRIPTION DRUG LABEL 16 0264-9011 INJECTION, SOLUTION 0.66 g INTRAVENOUS NDA 13 sections
TrophAmine HUMAN PRESCRIPTION DRUG LABEL 20 0264-9341 SOLUTION 0.78 g INTRAVENOUS NDA 12 sections
FreAmine HBC HUMAN PRESCRIPTION DRUG LABEL 15 0264-9350 INJECTION, SOLUTION 0.88 g INTRAVENOUS NDA 13 sections
TrophAmine HUMAN PRESCRIPTION DRUG LABEL 20 0264-9361 SOLUTION 0.47 g INTRAVENOUS NDA 12 sections
HepatAmine HUMAN PRESCRIPTION DRUG LABEL 16 0264-9371 INJECTION, SOLUTION 0.84 g INTRAVENOUS NDA 13 sections
ProSol HUMAN PRESCRIPTION DRUG LABEL 17 0338-0499 INJECTION, SOLUTION 1.44 g INTRAVENOUS NDA 12 sections
Clinisol HUMAN PRESCRIPTION DRUG LABEL 17 0338-0502 INJECTION, SOLUTION 960 mg INTRAVENOUS ANDA 11 sections
Travasol HUMAN PRESCRIPTION DRUG LABEL 15 0338-0644 INJECTION 580 mg INTRAVENOUS NDA 15 sections
CLINIMIX HUMAN PRESCRIPTION DRUG LABEL 16 0338-1083 INJECTION 160 mg INTRAVENOUS NDA 14 sections
CLINIMIX HUMAN PRESCRIPTION DRUG LABEL 16 0338-1089 INJECTION 247 mg INTRAVENOUS NDA 14 sections
CLINIMIX HUMAN PRESCRIPTION DRUG LABEL 16 0338-1091 INJECTION 247 mg INTRAVENOUS NDA 14 sections
CLINIMIX HUMAN PRESCRIPTION DRUG LABEL 16 0338-1093 INJECTION 247 mg INTRAVENOUS NDA 14 sections
CLINIMIX HUMAN PRESCRIPTION DRUG LABEL 16 0338-1095 INJECTION 247 mg INTRAVENOUS NDA 14 sections
CLINIMIX HUMAN PRESCRIPTION DRUG LABEL 16 0338-1099 INJECTION 290 mg INTRAVENOUS NDA 14 sections
CLINIMIX HUMAN PRESCRIPTION DRUG LABEL 16 0338-1101 INJECTION 290 mg INTRAVENOUS NDA 14 sections
CLINIMIX HUMAN PRESCRIPTION DRUG LABEL 15 0338-1103 INJECTION 290 mg INTRAVENOUS NDA 14 sections
CLINIMIX E HUMAN PRESCRIPTION DRUG LABEL 21 0338-1107 INJECTION 160 mg INTRAVENOUS NDA 15 sections
CLINIMIX E HUMAN PRESCRIPTION DRUG LABEL 21 0338-1109 INJECTION 160 mg INTRAVENOUS NDA 15 sections
CLINIMIX E HUMAN PRESCRIPTION DRUG LABEL 21 0338-1113 INJECTION 247 mg INTRAVENOUS NDA 15 sections
CLINIMIX E HUMAN PRESCRIPTION DRUG LABEL 21 0338-1115 INJECTION 247 mg INTRAVENOUS NDA 15 sections
CLINIMIX E HUMAN PRESCRIPTION DRUG LABEL 21 0338-1119 INJECTION 247 mg INTRAVENOUS NDA 15 sections
CLINIMIX E HUMAN PRESCRIPTION DRUG LABEL 21 0338-1123 INJECTION 290 mg INTRAVENOUS NDA 15 sections
CLINIMIX E HUMAN PRESCRIPTION DRUG LABEL 21 0338-1125 INJECTION 290 mg INTRAVENOUS NDA 15 sections
CLINIMIX E HUMAN PRESCRIPTION DRUG LABEL 21 0338-1127 INJECTION 290 mg INTRAVENOUS NDA 15 sections
Premasol - sulfite-free (Amino Acid) HUMAN PRESCRIPTION DRUG LABEL 19 0338-1130 INJECTION, SOLUTION 0.78 g INTRAVENOUS ANDA 12 sections