asparagine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4126 | 70-47-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONIA by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
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Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| CHEBI has role | CHEBI:27027 | trace elements |
| CHEBI has role | CHEBI:50733 | Dietary Supplement |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
| CHEBI has role | CHEBI:75772 | S. cerevisiae metabolites |
| CHEBI has role | CHEBI:76924 | plant metabolites |
| CHEBI has role | CHEBI:76971 | Escherichia coli metabolites |
| CHEBI has role | CHEBI:77746 | Homo sapiens metabolite |
| CHEBI has role | CHEBI:83056 | Daphnia magna metabolites |
| CHEBI has role | CHEBI:84735 | algal metabolites |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 2.1 | acidic |
| pKa2 | 12.1 | acidic |
| pKa3 | 8.83 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Amino acid transporter | Transporter | IC50 | 4.24 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| N0000170238 | NUI |
| D09738 | KEGG_DRUG |
| C0003995 | UMLSCUI |
| CHEBI:22653 | CHEBI |
| ASN | PDB_CHEM_ID |
| CHEMBL58832 | ChEMBL_ID |
| D001216 | MESH_DESCRIPTOR_UI |
| DB00174 | DRUGBANK_ID |
| 4533 | IUPHAR_LIGAND_ID |
| 5Z33R5TKO7 | UNII |
| 6267 | PUBCHEM_CID |
| 1157 | RXNORM |
| 006909 | NDDF |
| 87136001 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| EXODERMA Brightening Peeling Gel | HUMAN OTC DRUG LABEL | 2 | 83144-5721 | GEL | 2 g | TOPICAL | unapproved drug other | 8 sections |
| EXODERMA Brightening Mellow Foam | HUMAN OTC DRUG LABEL | 2 | 83144-8291 | GEL | 2 g | TOPICAL | unapproved drug other | 8 sections |
| EXODERMA Calming Toner Pad | HUMAN OTC DRUG LABEL | 2 | 83144-9251 | LIQUID | 2 g | TOPICAL | unapproved drug other | 8 sections |