levamlodipine Indications/Contra | FAERs | Orange Book | BioActivity |

Stem definitionDrug idCAS RN
calcium channel blockers, nifedipine derivatives 4099 103129-82-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • levamlodipine malate
  • levamlodipine besylate
  • (S)-amlodipine
  • levamlodipine
  • levoamlodipine
  • l-Amlodipine
used to treat angina and hypertension
  • Molecular weight: 408.88
  • Formula: C20H25ClN2O5
  • CLOGP: 3.43
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 2
  • TPSA: 99.88
  • ALOGS: -4.74
  • ROTB: 10

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.0 Basic
pKa2 1.55 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Voltage-gated L-type calcium channel Ion channel BLOCKER SCIENTIFIC LITERATURE SCIENTIFIC LITERATURE

External reference:

IDSource
0P6NLP6806 UNII
8835 INN_ID
D08941 KEGG_DRUG
d08466 MMSL
018248 NDDF
150566-71-5 SECONDARY_CAS_RN
C542574 MESH_SUPPLEMENTAL_RECORD_UI
DB09237 DRUGBANK_ID
CHEMBL2107350 ChEMBL_ID
CHEMBL2111097 ChEMBL_ID
9822750 PUBCHEM_CID

Pharmaceutical products:

None