sulfur hexafluoride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4039 | 2551-62-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Sulfur hexafluoride. An inert gas used mainly as a test gas in respiratory physiology. Other uses include its injection in vitreoretinal surgery to restore the vitreous chamber and as a tracer in monitoring the dispersion and deposition of air pollutants.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Oct. 10, 2014 | FDA | BRACCO |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Anaphylactic reaction | 118.03 | 64.33 | 39 | 747 | 32262 | 34923883 |
| Hyperhidrosis | 92.16 | 64.33 | 41 | 745 | 75651 | 34880494 |
| Contrast media reaction | 70.53 | 64.33 | 13 | 773 | 933 | 34955212 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Anaphylactic reaction | 133.06 | 56.05 | 51 | 1326 | 83692 | 79659319 |
| Contrast media reaction | 125.97 | 56.05 | 23 | 1354 | 2047 | 79740964 |
| Hyperhidrosis | 89.19 | 56.05 | 46 | 1331 | 151446 | 79591565 |
| Unresponsive to stimuli | 84.96 | 56.05 | 33 | 1344 | 55755 | 79687256 |
| Cardiac arrest | 67.47 | 56.05 | 40 | 1337 | 172056 | 79570955 |
| Pulse absent | 65.75 | 56.05 | 18 | 1359 | 10085 | 79732926 |
| Hypotension | 58.28 | 56.05 | 53 | 1324 | 440264 | 79302747 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | V08DA05 | VARIOUS CONTRAST MEDIA ULTRASOUND CONTRAST MEDIA Ultrasound contrast media |
| FDA MoA | N0000010259 | Ultrasound Contrast Activity |
| FDA EPC | N0000175864 | Contrast Agent for Ultrasound Imaging |
| CHEBI has role | CHEBI:76413 | greenhouse gases |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| N0000166210 | NUI |
| D05962 | KEGG_DRUG |
| 4035805 | VANDF |
| C0038779 | UMLSCUI |
| CHEBI:30496 | CHEBI |
| CHEMBL1796998 | ChEMBL_ID |
| D013459 | MESH_DESCRIPTOR_UI |
| DB11104 | DRUGBANK_ID |
| C420843 | MESH_SUPPLEMENTAL_RECORD_UI |
| C523090 | MESH_SUPPLEMENTAL_RECORD_UI |
| WS7LR3I1D6 | UNII |
| 17358 | PUBCHEM_CID |
| 1599276 | RXNORM |
| 22240 | MMSL |
| d05887 | MMSL |
| 010822 | NDDF |
| 259276004 | SNOMEDCT_US |
| 418601008 | SNOMEDCT_US |
| CHEMBL3545306 | ChEMBL_ID |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Lumason | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0270-7097 | INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION | 60.70 mg | INTRAVESICAL | NDA | 24 sections |
| Lumason | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0270-7097 | INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION | 60.70 mg | INTRAVESICAL | NDA | 24 sections |
| Lumason | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0270-7097 | INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION | 60.70 mg | INTRAVESICAL | NDA | 24 sections |
| Lumason | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0270-7097 | INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION | 60.70 mg | INTRAVESICAL | NDA | 24 sections |
| Lumason | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0270-7097 | INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION | 60.70 mg | INTRAVESICAL | NDA | 24 sections |
| Lumason | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0270-7097 | INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION | 60.70 mg | INTRAVESICAL | NDA | 24 sections |