sodium stibogluconate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4020 16037-91-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pentostam
  • sodium antimony gluconate
  • sodium stibogluconate
  • myostibin
  • solusurmin
  • stibatin
  • stibogluconate sodium
Antimony complex where the metal may exist in either the pentavalent or trivalent states. The pentavalent gluconate is used in leishmaniasis. The trivalent gluconate is most frequently used in schistosomiasis.
  • Molecular weight: 679.80
  • Formula: C12H20O17Sb2
  • CLOGP: -0.40
  • LIPINSKI: 3
  • HAC: 17
  • HDO: 8
  • TPSA: 276.27
  • ALOGS: -1.36
  • ROTB: 8

Drug dosage:

DoseUnitRoute
0.85 g P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC P01CB02 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS
Antimony compounds
MeSH PA D000871 Anthelmintics
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000977 Antiparasitic Agents
MeSH PA D000980 Antiplatyhelmintic Agents
MeSH PA D000981 Antiprotozoal Agents
MeSH PA D012556 Schistosomicides
CHEBI has role CHEBI:35610 antineoplastic agents
CHEBI has role CHEBI:70868 antileishmanial drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Leishmaniasis indication 80612004 DOID:9065




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D00582 KEGG_DRUG
C0030895 UMLSCUI
CHEBI:28148 CHEBI
CHEMBL2313755 ChEMBL_ID
CHEMBL2079699 ChEMBL_ID
CHEMBL3991035 ChEMBL_ID
CHEMBL2108095 ChEMBL_ID
DB05630 DRUGBANK_ID
16683012 PUBCHEM_CID
152209 RXNORM
004469 NDDF
324951006 SNOMEDCT_US
419379007 SNOMEDCT_US
D000967 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None