bornaprine indications/contra

Stem definitionDrug idCAS RN
390 20448-86-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bornaprine
  • bornaprine hydrochloride
  • bornaprine HCl
beneficial effect in Parkinsonism due to inhibition of muscarinic or nicotinic transmission
  • Molecular weight: 329.48
  • Formula: C21H31NO2
  • CLOGP: 5.26
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 0
  • TPSA: 29.54
  • ALOGS: -5.11
  • ROTB: 9

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC N04AA11 NERVOUS SYSTEM
ANTI-PARKINSON DRUGS
ANTICHOLINERGIC AGENTS
Tertiary amines
MeSH PA D018678 Cholinergic Agents
MeSH PA D018680 Cholinergic Antagonists
MeSH PA D018727 Muscarinic Antagonists
MeSH PA D018377 Neurotransmitter Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.11 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
C0053947 UMLSCUI
D07302 KEGG_DRUG
19610 RXNORM
003699 NDDF
9M363FGA7J UNII
3897 INN_ID
30160 PUBCHEM_CID
C006088 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL2104596 ChEMBL_ID
26908-91-8 SECONDARY_CAS_RN
CHEBI:135406 CHEBI

Pharmaceutical products:

None