bisulepine indications/contra

Stem definitionDrug idCAS RN
tricyclic compounds 383 5802-61-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bisulepin
  • bisulepine
  • dithiaden
  • Molecular weight: 301.47
  • Formula: C17H19NS2
  • CLOGP: 4.22
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 0
  • TPSA: 3.24
  • ALOGS: -4.75
  • ROTB: 3

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.66 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

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TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Histamine H1 receptor GPCR ANTAGONIST KEGG DRUG KEGG DRUG

External reference:

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IDSource
D07532 KEGG_DRUG
595726R32U UNII
6537425 PUBCHEM_CID
CHEBI:135277 CHEBI

Pharmaceutical products:

None