binifibrate indications/contra

Stem definitionDrug idCAS RN
clofibrate derivatives 372 69047-39-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • binifibrate
  • biniwas
two nicotinic & one clofibiric radical esterified by glycerol moiety
  • Molecular weight: 498.92
  • Formula: C25H23ClN2O7
  • CLOGP: 4.12
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 0
  • TPSA: 113.91
  • ALOGS: -4.77
  • ROTB: 13

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
MeSH PA D000963 Antimetabolites
MeSH PA D000960 Hypolipidemic Agents
MeSH PA D057847 Lipid Regulating Agents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.34 Basic
pKa2 2.74 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
D07529 KEGG_DRUG
9NGZ4GPE20 UNII
4956 INN_ID
68884 PUBCHEM_CID
C038877 MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL2106582 ChEMBL_ID
CHEBI:135800 CHEBI

Pharmaceutical products:

None