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2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
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Redial
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L1000
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
acadesine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
37
2627-69-2
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
aminoimidazole carboxamide ribonucleoside
5-aminoimidazole-4-carboxamide riboside
acadesine
arasine
Molecular weight: 258.23
Formula: C9H14N4O5
CLOGP: -2.33
LIPINSKI: 0
HAC: 9
HDO: 5
TPSA: 156.85
ALOGS: -1.01
ROTB: 3
Drug dosage:
None
ADMET properties:
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Property
Value
Reference
BA (Bioavailability)
10 %
Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
C01EB13
CARDIOVASCULAR SYSTEM
CARDIAC THERAPY
OTHER CARDIAC PREPARATIONS
Other cardiac preparations
CHEBI has role
CHEBI:35610
antineoplastic agents
CHEBI has role
CHEBI:50427
platelet aggregation inhibitors
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
11.55
acidic
pKa2
11.83
acidic
pKa3
12.51
acidic
pKa4
13.19
acidic
pKa5
4.67
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
17513
PUBCHEM_CID
5133
IUPHAR_LIGAND_ID
53IEF47846
UNII
6758
INN_ID
C0051027
UMLSCUI
C011651
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:28498
CHEBI
CHEMBL1551724
ChEMBL_ID
D02742
KEGG_DRUG
DB04944
DRUGBANK_ID
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Pharmaceutical products:
None
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acadesine