acadesine indications/contra

Stem definitionDrug idCAS RN
37 2627-69-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • aminoimidazole carboxamide ribonucleoside
  • 5-aminoimidazole-4-carboxamide riboside
  • acadesine
  • arasine
  • Molecular weight: 258.23
  • Formula: C9H14N4O5
  • CLOGP: -2.33
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 5
  • TPSA: 156.85
  • ALOGS: -1.01
  • ROTB: 3

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC C01EB13 CARDIOVASCULAR SYSTEM
CARDIAC THERAPY
OTHER CARDIAC PREPARATIONS
Other cardiac preparations
CHEBI has role CHEBI:50427 platelet aggregation inhibitor
CHEBI has role CHEBI:35610 antineoplastic agent

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

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Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.55 acidic
pKa2 11.83 acidic
pKa3 12.51 acidic
pKa4 13.19 acidic
pKa5 4.67 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
5133 IUPHAR_LIGAND_ID
D02742 KEGG_DRUG
53IEF47846 UNII
6758 INN_ID
17513 PUBCHEM_CID
CHEBI:28498 CHEBI
CHEMBL1551724 ChEMBL_ID
C011651 MESH_SUPPLEMENTAL_RECORD_UI
DB04944 DRUGBANK_ID

Pharmaceutical products:

None