azacyclonol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3680 115-46-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • azacyclonol
  • ataractan
  • calmeran
  • azacyclonol hydrochloride
  • frenquel
  • azacyclonol HCl
major descriptor (65-84); on-line search PIPERIDINES (65-84); Index Medicus search AZACYCLONOL (65-84); RN given refers to parent cpd
  • Molecular weight: 267.37
  • Formula: C18H21NO
  • CLOGP: 2.55
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 2
  • TPSA: 32.26
  • ALOGS: -4.05
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.21 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Histamine H1 receptor GPCR Ki 6.18 CHEMBL
Sodium channel alpha subunits; brain (Types I, II, III) Ion channel IC50 4.85 CHEMBL

External reference:

IDSource
C0175156 UMLSCUI
CHEBI:93706 CHEBI
CHEMBL127508 ChEMBL_ID
C100095 MESH_SUPPLEMENTAL_RECORD_UI
15723 PUBCHEM_CID
655 INN_ID
1798-50-1 SECONDARY_CAS_RN
2MMR990PEM UNII
3142009 SNOMEDCT_US
CHEMBL2105900 ChEMBL_ID

Pharmaceutical products:

None