triclocarban 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 3630 | 101-20-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
bacteriostat; antiseptic in soaps & other cleansing solns; germicide; structure
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000891 | Anti-Infective Agents, Local |
| MeSH PA | D004785 | Environmental Pollutants |
| MeSH PA | D014874 | Water Pollutants, Chemical |
| CHEBI has role | CHEBI:33281 | antibiotics |
| CHEBI has role | CHEBI:35703 | Xenobiotic |
| CHEBI has role | CHEBI:48218 | antiseptics |
| CHEBI has role | CHEBI:48219 | disinfectants |
| CHEBI has role | CHEBI:78298 | environmental contaminants |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 11.93 | acidic |
| pKa2 | 12.5 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Bifunctional epoxide hydrolase 2 | Enzyme | IC50 | 7.89 | CHEMBL | |||||
| Epoxide hydrolase 1 | Enzyme | IC50 | 6.92 | CHEMBL | |||||
| Epoxide hydrolase; Epoxide hydrolase EphB | Enzyme | IC50 | 6.66 | CHEMBL | |||||
| Epoxide hydrolase 1 | Enzyme | IC50 | 6.44 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D06223 | KEGG_DRUG |
| C0077072 | UMLSCUI |
| CHEBI:48347 | CHEBI |
| 9EG | PDB_CHEM_ID |
| CHEMBL1076347 | ChEMBL_ID |
| DB11155 | DRUGBANK_ID |
| C009540 | MESH_SUPPLEMENTAL_RECORD_UI |
| 7547 | PUBCHEM_CID |
| 2017 | INN_ID |
| BGG1Y1ED0Y | UNII |
| 38609 | RXNORM |
| 003183 | NDDF |
| 23701001 | SNOMEDCT_US |
| 411346009 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Dial Gold BarAntibacterial Deodorant Soap | HUMAN OTC DRUG LABEL | 1 | 10889-100 | SOAP | 0.60 1 | CUTANEOUS | OTC monograph not final | 16 sections |
| DG BodyAntibacterial Deodorant 3.5 oz bar | HUMAN OTC DRUG LABEL | 1 | 10889-301 | SOAP | 0.60 1 | CUTANEOUS | OTC monograph not final | 14 sections |
| Rite Aid Renewal Gold Deodorant | HUMAN OTC DRUG LABEL | 1 | 11822-8453 | SOAP | 0.30 g | TOPICAL | OTC monograph not final | 10 sections |
| Luckyantibacterial deodorant | HUMAN OTC DRUG LABEL | 1 | 20276-048 | SOAP | 0.30 g | TOPICAL | OTC monograph not final | 10 sections |
| Personal Care Antibacterial | HUMAN OTC DRUG LABEL | 1 | 29500-9208 | SOAP | 0.67 g | TOPICAL | OTC monograph not final | 11 sections |
| Image Essentials Gold | HUMAN OTC DRUG LABEL | 1 | 49738-731 | SOAP | 0.30 g | TOPICAL | OTC monograph not final | 8 sections |
| Dial antibacterial | HUMAN OTC DRUG LABEL | 1 | 51815-300 | SOAP | 0.34 g | TOPICAL | OTC monograph not final | 7 sections |
| DialWhite | HUMAN OTC DRUG LABEL | 1 | 51815-301 | SOAP | 113 g | TOPICAL | OTC monograph not final | 8 sections |
| Dial Aloe Aloe | HUMAN OTC DRUG LABEL | 1 | 51815-302 | SOAP | 1.02 g | TOPICAL | OTC monograph not final | 8 sections |
| Dial Odor ArmorOdor Armor | HUMAN OTC DRUG LABEL | 1 | 51815-303 | SOAP | 1.02 g | TOPICAL | OTC monograph not final | 9 sections |
| Antibacterial Golden Burst | HUMAN OTC DRUG LABEL | 1 | 52862-120 | SOAP | 0.30 g | TOPICAL | OTC monograph not final | 11 sections |
| Antibacterial Ocean Fresh | HUMAN OTC DRUG LABEL | 1 | 52862-130 | SOAP | 0.30 g | TOPICAL | OTC monograph not final | 11 sections |
| DEODORANT | HUMAN OTC DRUG LABEL | 1 | 53507-001 | SOAP | 0.29 g | TOPICAL | OTC monograph not final | 7 sections |
| MegaFresh Antibacterial Deodorant | HUMAN OTC DRUG LABEL | 1 | 54157-101 | SOAP | 0.30 g | TOPICAL | OTC monograph not final | 8 sections |
| Dollar General Gold | HUMAN OTC DRUG LABEL | 1 | 55910-301 | SOAP | 0.60 g | TOPICAL | OTC monograph not final | 9 sections |
| Coralite Ultra Antibacterial Deodorant | HUMAN OTC DRUG LABEL | 1 | 65923-807 | SOAP | 0.30 g | TOPICAL | OTC monograph not final | 10 sections |
| Antibacterial Gold | HUMAN OTC DRUG LABEL | 1 | 67510-0016 | SOAP | 0.10 g | TOPICAL | OTC monograph not final | 8 sections |
| Antibacterial Beauty | HUMAN OTC DRUG LABEL | 1 | 67510-0017 | SOAP | 0.10 g | TOPICAL | OTC monograph not final | 8 sections |
| 1st Date antibacterial Deodorant (White) | HUMAN OTC DRUG LABEL | 1 | 70012-101 | SOAP | 0.30 g | TOPICAL | OTC monograph not final | 10 sections |
| 1st Date antibacterial Deodorant (Gold) | HUMAN OTC DRUG LABEL | 1 | 70012-102 | SOAP | 0.30 g | TOPICAL | OTC monograph not final | 10 sections |
| 1st Date antibacterial Deodorant (Green) | HUMAN OTC DRUG LABEL | 1 | 70012-103 | SOAP | 0.30 g | TOPICAL | OTC monograph not final | 10 sections |