trichloroethylene 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3628 79-01-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • trichloroethylene
  • ethylene trichloride
  • 1,1,2-Trichloroethylene
  • chlorilen
  • trichloroethene
A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment.
  • Molecular weight: 131.38
  • Formula: C2HCl3
  • CLOGP: 2.63
  • LIPINSKI: 0
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS: -1.83
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N01AB05 NERVOUS SYSTEM
ANESTHETICS
ANESTHETICS, GENERAL
Halogenated hydrocarbons
MeSH PA D000777 Anesthetics
MeSH PA D018685 Anesthetics, Inhalation
MeSH PA D002491 Central Nervous System Agents
MeSH PA D002492 Central Nervous System Depressants
MeSH PA D012997 Solvents
CHEBI has role CHEBI:38870 inhalation anesthetics
CHEBI has role CHEBI:75771 Mus musculus metabolites

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0040905 UMLSCUI
CHEBI:16602 CHEBI
CHEMBL279816 ChEMBL_ID
6575 PUBCHEM_CID
DB13323 DRUGBANK_ID
D014241 MESH_DESCRIPTOR_UI
2131 INN_ID
290YE8AR51 UNII
2534464 RXNORM
NOCODE MMSL
001395 NDDF
16808006 SNOMEDCT_US
333887003 SNOMEDCT_US
TCV PDB_CHEM_ID

Pharmaceutical products:

None