betamipron indications/contra

Stem definitionDrug idCAS RN
355 3440-28-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • betamipron
  • 3-Benzamidopropionic acid
  • Benzoyl-beta-alanine
  • Molecular weight: 193.20
  • Formula: C10H11NO3
  • CLOGP: 0.72
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 66.40
  • ALOGS: -2.34
  • ROTB: 4

Drug dosage:

DoseUnitRoute
2 g P

Approvals:

DateAgencyCompanyOrphan
Jan. 1, 1993 YEAR INTRODUCED

FDA Adverse Event Reporting System

None

Pharmacologic Action:

scroll-->
SourceCodeDescription
ATC J01DH55 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
OTHER BETA-LACTAM ANTIBACTERIALS
Carbapenems

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

scroll-->
Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.08 acidic
pKa2 12.18 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

scroll-->
TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Solute carrier family 22 member 8 Transporter Ki 4.32 WOMBAT-PK
Solute carrier family 22 member 6 Transporter Ki 4.62 WOMBAT-PK

External reference:

scroll-->
IDSource
CHEBI:31278 CHEBI
D01331 KEGG_DRUG
3W0M245736 UNII
6741 INN_ID
71651 PUBCHEM_CID
CHEMBL1231530 ChEMBL_ID
C047207 MESH_SUPPLEMENTAL_RECORD_UI
BYA PDB_CHEM_ID

Pharmaceutical products:

None