phenoxyethanol Indications/Contra | FAERs | Orange Book | BioActivity |

Stem definitionDrug idCAS RN
3442 122-99-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • 2-phenoxyethanol
  • (2-Hydroxyethoxy)benzene
  • ethylene glycol monophenyl ether
  • phenoxethol
  • phenoxyethyl alcohol
  • phenoxyethanol
  • Molecular weight: 138.17
  • Formula: C8H10O2
  • CLOGP: 1.19
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 29.46
  • ALOGS: -0.76
  • ROTB: 3

Drug dosage:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Completed suicide 11358.81 247.30 2345 3848 28769 3350897
Drug abuse 6967.31 247.30 1451 4742 16879 3362787
Toxicity to various agents 6771.74 247.30 1680 4513 45374 3334292
Respiratory arrest 2705.70 247.30 621 5572 10747 3368919
Cardio-respiratory arrest 2685.81 247.30 654 5539 14786 3364880
Poisoning 2541.33 247.30 513 5680 4599 3375067
Cardiac arrest 2412.20 247.30 675 5518 26644 3353022
Death 2235.43 247.30 980 5213 151344 3228322
Intentional product misuse 1775.25 247.30 453 5740 12248 3367418
Exposure via ingestion 1162.46 247.30 219 5974 1274 3378392
Intentional overdose 1104.93 247.30 325 5868 14900 3364766
Overdose 940.13 247.30 350 5843 33628 3346038
Alcohol use 302.33 247.30 71 6122 1300 3378366
Suicide attempt 297.80 247.30 124 6069 15723 3363943
Alcohol poisoning 274.11 247.30 59 6134 712 3378954
Poisoning deliberate 251.69 247.30 58 6135 973 3378693

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:35441 antiinfective agent
CHEBI has role CHEBI:35488 central nervous system depressant
MeSH PA D000777 Anesthetics
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
MeSH PA D002491 Central Nervous System Agents
MeSH PA D002492 Central Nervous System Depressants

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Antiseptic preparation indication 261276004

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEBI:64275 CHEBI
C0301042 UMLSCUI
D08359 KEGG_DRUG
NOCODE MMSL
424614001 SNOMEDCT_US
84103009 SNOMEDCT_US
003752 NDDF
89552 RXNORM
CHEMBL1229846 ChEMBL_ID
HIE492ZZ3T UNII
C005398 MESH_SUPPLEMENTAL_RECORD_UI
DB11304 DRUGBANK_ID
31236 PUBCHEM_CID
268 PDB_CHEM_ID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
MANUGEL 85 HUMAN OTC DRUG LABEL 2 62169-202 GEL 0.30 g TOPICAL OTC monograph not final 7 sections