orotic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3402 65-86-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • orotic acid
  • orotonin
  • oroturic
  • orotyl
  • Vitamin B13
  • 6-Uracilcarboxylic acid
An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
  • Molecular weight: 156.10
  • Formula: C5H4N2O4
  • CLOGP: -0.75
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 3
  • TPSA: 95.50
  • ALOGS: -1.54
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:25212 metabolites
CHEBI has role CHEBI:75771 Mus musculus metabolites
CHEBI has role CHEBI:76971 Escherichia coli metabolites

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.48 acidic
pKa2 9.11 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000167335 NUI
D00055 KEGG_DRUG
C0029300 UMLSCUI
CHEBI:16742 CHEBI
ORO PDB_CHEM_ID
CHEMBL1235017 ChEMBL_ID
DB02262 DRUGBANK_ID
D009963 MESH_DESCRIPTOR_UI
967 PUBCHEM_CID
3502 INN_ID
4690 IUPHAR_LIGAND_ID
61H4T033E5 UNII
7712 RXNORM
006148 NDDF
2254005 SNOMEDCT_US

Pharmaceutical products:

None